Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Wei Jennifer Yang"'
Publikováno v:
Journal of Biological Chemistry. 280:9330-9335
Dicer is a multi-domain protein responsible for the generation of short interfering RNAs (siRNAs) from long double-stranded RNAs during RNA interference. It is also involved in the maturation of microRNAs, some of which are transcriptional regulators
Autor:
Jeeyun Lee, Yuli Wang, Tao Xie, Cheol-Keun Park, David Pocalyko, Stephanie T. Shi, Wei Jennifer Yang, Paul A. Rejto, Zhou Zhu, Jiangchun Xu, Ho Yeong Lim, Kai Wang, Shibing Deng, Mao Mao
Publikováno v:
Hepatology (Baltimore, Md.). 58(2)
Cancer is a genetic disease with frequent somatic DNA alterations. Studying recurrent copy number aberrations (CNAs) in human cancers would enable the elucidation of disease mechanisms and the prioritization of candidate oncogenic drivers with causal
Autor:
Chi-Kin Chow, Jirong Lu, Sudhakar Chintharlapalli, Ling Liu, Wei Zeng, Irene Denning, Julian Davies, Wei Jennifer Yang, Lei Yan, Spring Weir, Peter Edward Vaillancourt, Mcclure Don B, Victoria L. Peek, Mark Wortinger
Publikováno v:
Cancer Research. 70:2583-2583
The receptor tyrosine kinase c-Met and its ligand HGF elicit multiple cellular activities including cell proliferation, motility, invasion, tubulogenesis, angiogenesis and anti-apoptosis. Dysregulation of this pathway has emerged as a crucial feature
Autor:
Wei Jennifer Yang, James E. Wooldridge, Julian Davies, Irene Denning, Victoria L. Peek, Spring Weir, Chi-Kin Chow, Wei Zeng, Jirong Lu, Lei Yan, Peter Edward Vaillancourt, Ling Liu, Mark Wortinger
Publikováno v:
Cancer Research. 70:695-695
c-Met is a receptor tyrosine kinase that binds hepatocyte growth factor (HGF) and has been implicated in human cancer. Inappropriate activation of c-Met can be induced by ligand-independent mechanisms such as gene amplification, specific genetic muta