Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Wei Cun See Too"'
Publikováno v:
AIMS Biophysics, Vol 11, Iss 3, Pp 281-295 (2024)
Cervical cancer remains a significant global health challenge, especially in low- and middle-income countries. The elucidation of the molecular pathways underlying the carcinogenesis of cervical cancer is vital to develop targeted therapies. Our stud
Externí odkaz:
https://doaj.org/article/c4479dcb1578493393dcb1c6193809f3
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154702 (2016)
Choline kinase beta (CKβ) is one of the CK isozymes involved in the biosynthesis of phosphatidylcholine. CKβ is important for normal mitochondrial function and muscle development as the lack of the ckβ gene in human and mice results in the develop
Externí odkaz:
https://doaj.org/article/be3801881c5d4c2dbe85777ad2721a77
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147886 (2016)
Ethanolamine kinase (EK) catalyzes the phosphorylation of ethanolamine, the first step in the CDP-ethanolamine pathway for the biosynthesis of phosphatidylethanolamine (PE). Human EK exists as EK1, EK2α and EK2β isoforms, encoded by two separate ge
Externí odkaz:
https://doaj.org/article/7c1f7ccad9a643e1ba670374234f99ff
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e113485 (2014)
Choline kinase is the most upstream enzyme in the CDP-choline pathway. It catalyzes the phosphorylation of choline to phosphorylcholine in the presence of ATP and Mg2+ during the biosynthesis of phosphatidylcholine, the major phospholipid in eukaryot
Externí odkaz:
https://doaj.org/article/4afefc6578e24e4e826b72978b452d10
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e12999 (2010)
BackgroundCholine kinase is the first enzyme in the CDP-choline pathway that synthesizes phosphatidylcholine, the major phospholipid in eukaryotic cell membranes. In humans, choline kinase exists as three isoforms (CKα1, α2, and β). Specific inhib
Externí odkaz:
https://doaj.org/article/95288dc810b84d8daa3a664c3698d074
Autor:
Chiat Han Chang, Ling Ling Few, Boon Huat Lim, Get Bee Yvonne-Tee, Ai Lan Chew, Wei Cun See Too
Publikováno v:
Parasitology Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7850cff85781a97f1506437f1166c1d
https://doi.org/10.1007/s00436-023-07869-5
https://doi.org/10.1007/s00436-023-07869-5
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 22:1281-1288
Background:: Pseudomonas aeruginosa is one of the most prevalent opportunistic pathogens in humans that has thrived and proved to be difficult to control in this “post-antibiotic era.” Antibiotic alternatives are necessary for fighting against th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2761849d19ed4aca4b7cd0b4b1b44c43
https://doi.org/10.2174/1389557521666211213160256
https://doi.org/10.2174/1389557521666211213160256
Autor:
Sweta Raikundalia, Wei Cun See Too, Ling Ling Few, Siti Aisyah Faten Mohamed Sa'dom, Shaharum Shamsuddin
Publikováno v:
Genes
Genes, Vol 12, Iss 853, p 853 (2021)
Volume 12
Issue 6
Genes, Vol 12, Iss 853, p 853 (2021)
Volume 12
Issue 6
Choline kinase (CK) is the enzyme catalyzing the first reaction in CDP-choline pathway for the biosynthesis of phosphatidylcholine. Higher expression of the α isozyme of CK has been implicated in carcinogenesis, and inhibition or downregulation of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6734bf05cb277177edd763bd1420d7f7
http://europepmc.org/articles/PMC8229565
http://europepmc.org/articles/PMC8229565
Publikováno v:
Oncology Letters
Choline kinase (ChK) catalyzes the first step in the CDP-choline pathway for the synthesis of phosphatidylcholine. The α isoform of this enzyme is overexpressed in various types of cancer and its inhibition or downregulation has been applied as an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180ca934058360b848e86d373984036a
http://europepmc.org/articles/PMC7816280
http://europepmc.org/articles/PMC7816280
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2020 (2020)
BioMed Research International, Vol 2020 (2020)
Novel antimicrobial agents are crucial to combat antibiotic resistance in pathogenic bacteria. Choline kinase (ChoK) in bacteria catalyzes the synthesis of phosphorylcholine, which is subsequently incorporated into the cell wall or outer membrane. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2775b7ef3c81ad204a8e975846f6c6
https://pubmed.ncbi.nlm.nih.gov/32695809
https://pubmed.ncbi.nlm.nih.gov/32695809