Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Wei⁃hong GU"'
Autor:
Wen-Zheng Hu, Ling-Xiao Cao, Jin-Hui Yin, Xue-Song Zhao, Ying-Shan Piao, Wei-Hong Gu, Jing-Hong Ma, Zhi-Rong Wan, Yue Huang
Publikováno v:
Frontiers in Neurology, Vol 13 (2023)
BackgroundNon-motor symptoms (NMS) are compulsory clinical features for the clinical diagnosis of multiple system atrophy (MSA), some of which precede motor symptoms onset. To date, few studies have systematically investigated NMS in MSA and the timi
Externí odkaz:
https://doaj.org/article/e6746433cfba45b9a92dbc9b3c1c0e15
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 19, Iss 6, Pp 419-422 (2019)
Objective To investigate the clinical phenotype and genotype manifestations of autosomal recessive hereditary spastic ataxia 2 (SPAX2), to help physicians recognize this disease. Methods and Results A 35-year-old male patient presented with postural
Externí odkaz:
https://doaj.org/article/bf176d16ff2c43c4a8546d92fb2cfce5
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 19, Iss 6, Pp 411-418 (2019)
Objective To summarize phenotype, treatment principles and prognosis of 4 patients from 2 pedigrees with late-onset methylmalonic aciduria (MMA) and homocystinuria cobalamin C (cblC) type, so as to explore the pathophysiological mechanism of this dis
Externí odkaz:
https://doaj.org/article/c05bad41bb364f77a381be77ce43e7aa
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 18, Iss 3, Pp 192-197 (2018)
Objective To estimate the accuracy and stability of capillary electrophoresis fragment analysis and clone sequencing in detecting dynamic mutations of spinocerebellar ataxia (SCA). Methods Capillary electrophoresis fragment analysis and clone sequenc
Externí odkaz:
https://doaj.org/article/4a160f38d0914371802c1224996a2ca3
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 17, Iss 8, Pp 597-602 (2017)
Objective To investigate the clinical features and dynamic mutation of 10 cases with juvenile-onset Huntington's disease (HD). Methods The cytosine-adenine-guanine (CAG) repeats of IT15 gene were detected by polymerase chain reaction (PCR) and capill
Externí odkaz:
https://doaj.org/article/8058973e9ad345e6b8e222d11b3dcc3d
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 17, Iss 7, Pp 513-518 (2017)
Objective To make the diagnosis for a patient presented with head tremor and cerebellar atrophy by integrating clinical features and accessory examination with genetic testing and to explore the interpretation of genetic testing results. Methods A 30
Externí odkaz:
https://doaj.org/article/ede397c2672b4d31939a5b46e3a497ea
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 15, Iss 5, Pp 406-410 (2015)
Objective In the present experiment we investigate the behavior of 4-month-old transgenic APP/PS-1/tau mice model with Alzheimer's disease (3 × Tg-AD mice) to evaluate their abilities of spatial learning and memory. We observe the changes of synapti
Externí odkaz:
https://doaj.org/article/b14b985a52f24f2596334ae9b2d521a4
Autor:
Li WANG, Qi-jiang FAN, Ming-rui DONG, Zhao-hui TIAN, Ren-bin WANG, Wei-hong GU, Zun-jing LIU, Qing SUN, Jin-song JIAO
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 16, Iss 8, Pp 533-535 (2016)
DOI: 10.3969/j.issn.1672-6731.2016.08.013
Externí odkaz:
https://doaj.org/article/c8bb0d5f38194baf8aecfa0a051f2d64
Autor:
Lin-wei ZHANG, Wei-hong GU
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 14, Iss 5, Pp 450-454 (2014)
Spinocerebellar ataxia type 1 (SCA1) is a kind of autosomal dominant genetic neurodegenerative disorder. To date, the pathogenesis of SCA1 remains unclear. Studies in numerous SCA1 experimental models, including transgenic mice, transgenic drosophila
Externí odkaz:
https://doaj.org/article/0e010068c0c645138cebe95e9e4d12c0
Autor:
Li WANG, Tuan-feng YANG, Min CHENG, Yuan LI, Qian WANG, Jin-song JIAO, Wei-hong GU, Kang WANG, Miao JIN, Huai-lian GUO
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 14, Iss 3, Pp 257-262 (2014)
Background 131I-metaiodobenzylguanidine (131I-MIBG) can be intaked by cardiac sympathetic postganglionic fibre, thus becomes the imaging agent to evaluate cardiac sympathetic nerve function. The aim of this study is to investigate the autonomic nerve
Externí odkaz:
https://doaj.org/article/7ff8f1ff123143c2a7f9b4b04e4e80b4