Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Wei‑Xin Hu"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 50, Iss , Pp 100974- (2024)
Multiple myeloma is a hematological malignancy that has evolved from antibody-secreting B lymphocytes. Like other types of cancers, myeloma cells have acquired functional capabilities which are referred to as “Hallmarks of Cancer”, and one of the
Externí odkaz:
https://doaj.org/article/227a84417ffe40e18358e61f886668ea
Autor:
Yu Rong, Shan-Shan Dong, Wei-Xin Hu, Yan Guo, Yi-Xiao Chen, Jia-Bin Chen, Dong-Li Zhu, Hao Chen, Tie-Lin Yang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 3650-3657 (2021)
Detecting SNPs associated with drug efficacy or toxicity is helpful to facilitate personalized medicine. Previous studies usually find SNPs associated with clinical outcome only in patients received a specific treatment. However, without information
Externí odkaz:
https://doaj.org/article/af455adbb21c44d2be4855f58656ba41
Publikováno v:
Memorias do Instituto Oswaldo Cruz, Vol 108, Iss 7, Pp 865-872 (2013)
Schistosomiasis is an endemic parasite disease and praziquantel is the only drug currently in use to control this disease. Experimental and epidemiological evidence strongly suggests that Microtus fortis ( Mf ) is a naturally resistant vertebrate hos
Externí odkaz:
https://doaj.org/article/0c9e3ae359d14af3aef61db8aef0bba8
Autor:
Sai-Qun Luo, Jing-Ping Hu, Qiang Qu, Jiang Li, Wei Ren, Jia-Ming Zhang, Yan Zhong, Wei-Xin Hu
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40475 (2012)
Our previous studies had shown that DAZAP2 was profoundly downregulated in bone marrow mononuclear cells from multiple myeloma patients. In this report, we analyzed epigenetic changes in multiple myeloma cell lines to understand the molecular mechani
Externí odkaz:
https://doaj.org/article/e68aaca0e62840ab8f79c1f0f3dc6fd7
Publikováno v:
BMC Cancer, Vol 6, Iss 1, p 66 (2006)
Abstract Background HSVtk/ganciclovir (GCV) gene therapy has been extensively studied in tumors and relies largely on the gene expression of HSVtk. Most studies, however, have failed to demonstrate any significant benefit of a controlled gene express
Externí odkaz:
https://doaj.org/article/75147aa1ecbd4111a4f3bf5736df832e
Autor:
Hao Chen, Dong-Li Zhu, Yu Rong, Yi-Xiao Chen, Tie-Lin Yang, Wei-Xin Hu, Yan Guo, Jia-Bin Chen, Shan-Shan Dong
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3650-3657 (2021)
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 3650-3657 (2021)
Graphical abstract
Detecting SNPs associated with drug efficacy or toxicity is helpful to facilitate personalized medicine. Previous studies usually find SNPs associated with clinical outcome only in patients received a specific treatment. Howev
Detecting SNPs associated with drug efficacy or toxicity is helpful to facilitate personalized medicine. Previous studies usually find SNPs associated with clinical outcome only in patients received a specific treatment. Howev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01649883e4f135e73baaf3bc487039d7
https://doi.org/10.1016/j.csbj.2021.06.026
https://doi.org/10.1016/j.csbj.2021.06.026
Publikováno v:
The FASEB Journal. 36
Multiple myeloma (MM), the terminally differentiated B cells malignancy, is widely considered to be incurable since many patients have either developed drug resistance or experienced an eventual relapse. To develop precise and efficient therapeutic s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::effaf8ee084f90821cc21b87b7f9918b
https://doi.org/10.1096/fj.202200354
https://doi.org/10.1096/fj.202200354
Autor:
Xiao-Feng Chen, Nai-Ning Wang, Shan-Shan Dong, Hao Chen, Fu-Ling Zhou, Ruo-Han Hao, Yi-Xiao Chen, Tie-Lin Yang, Ming-Rui Guo, Yan Guo, Yuan-Yuan Duan, Shi Yao, Jia-Bin Chen, Wei-Xin Hu, Yu Rong, Yu-Jie Zhang, Hlaing Nwe Thynn
Publikováno v:
Bioinformatics. 36:4739-4748
Motivation CircRNAs are an abundant class of non-coding RNAs with widespread, cell-/tissue-specific patterns. Previous work suggested that epigenetic features might be related to circRNA expression. However, the contribution of epigenetic changes to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d3100ee9cee642ab3e1309469a663a
https://doi.org/10.1093/bioinformatics/btaa567
https://doi.org/10.1093/bioinformatics/btaa567
Autor:
Xiu-Fen Bu, Jia-Ming Zhang, Wei-Xin Hu, Jiang Li, Saiqun Luo, De-Hui Xiong, Yali Wang, Guangdi Li, Jingping Hu
Publikováno v:
Oncogene. 39:3354-3366
Multiple myeloma (MM) is a clinically and biologically heterogenous event that accounts for approximately 10% of all hematological malignancies. Chromosome 1 open reading frame 35 (C1orf35) is a gene cloned and identified in our laboratory from a MM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622aec8aa55228d0031285b504b6ea82
https://doi.org/10.1038/s41388-020-1222-7
https://doi.org/10.1038/s41388-020-1222-7
Publikováno v:
Briefings in bioinformatics. 23(5)
Clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 gene editing technology has been widely used to facilitate efficient genome editing. Current popular sgRNA design tools only consider the sgRNA perfectly matched to the target si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdc33e36e3171428480353e20eb2f80
https://pubmed.ncbi.nlm.nih.gov/35580855
https://pubmed.ncbi.nlm.nih.gov/35580855