Zobrazeno 1 - 10
of 209
pro vyhledávání: '"Wei‐Qun Ding"'
Autor:
Yang Feng, Yahui Feng, Liming Gu, Wei Mo, Xi Wang, Bin Song, Min Hong, Fenghao Geng, Pei Huang, Hongying Yang, Wei Zhu, Yang Jiao, Qi Zhang, Wei-Qun Ding, Jianping Cao, Shuyu Zhang
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 5, Pp 1107-1122 (2024)
Abstract Genotoxic therapy triggers reactive oxygen species (ROS) production and oxidative tissue injury. S-nitrosylation is a selective and reversible posttranslational modification of protein thiols by nitric oxide (NO), and 5,6,7,8-tetrahydrobiopt
Externí odkaz:
https://doaj.org/article/a9301964e7344741a1983dbe87c4ee4a
Publikováno v:
Tobacco Induced Diseases, Vol 21, Iss August, Pp 1-14 (2023)
Introduction Both cigarette smoking and gut microbiota play important roles in colorectal carcinogenesis. We explored whether the association between smoking and colorectal cancer (CRC) risk varies by gut microbial enterotypes and how smoking-related
Externí odkaz:
https://doaj.org/article/fdf9a47f29ab4b958a798173bf384b67
Autor:
Xiaoqing Li, Dexuan Gao, Fei Shen, Hengrui Chen, Zhuqiang Zhang, Chao He, Aidi Gao, Yue Lang, Xiaozhong Zhu, Jundong Zhou, Zeng-Fu Shang, Wei-Qun Ding, Ji Zhu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Radiotherapy resistance is an important and urgent challenge in the clinical management of esophageal squamous carcinoma (ESCC). However, the factors mediating the ESCC resistance to radiotherapy and its underlying molecular mechanisms are n
Externí odkaz:
https://doaj.org/article/86de10f4a735478fb79f810fb4754bee
Autor:
Yuandong Cao, Aidi Gao, Xiaoqing Li, Han Min, Chao He, Xinchen Sun, Wei‐Qun Ding, Jundong Zhou
Publikováno v:
Cancer Medicine, Vol 10, Iss 9, Pp 3101-3112 (2021)
Abstract Background Radiotherapy is one of the main strategies for the treatment of esophageal squamous cell carcinoma (ESCC). However, treatment failure often occurs due to the emergence of radioresistance. In this study, we report a key regulator o
Externí odkaz:
https://doaj.org/article/765c4a42965c4ae69f52c6c6ec7b320f
Autor:
Yi-Fan Xu, Xiaohui Xu, Amy Gin, Jean D. Nshimiyimana, Blaine H. M. Mooers, Massimo Caputi, Bethany N. Hannafon, Wei-Qun Ding
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-13 (2020)
Abstract Background Exosomes are extracellular vesicles containing a variety of biological molecules including microRNAs (miRNAs). We have recently demonstrated that certain miRNA species are selectively and highly enriched in pancreatic cancer exoso
Externí odkaz:
https://doaj.org/article/a8f820413b73491fb77428c5cff368ea
Autor:
Zhenzi Su, Aidi Gao, Xiaoqing Li, Shitao Zou, Chao He, Jinchang Wu, Wei-Qun Ding, Jundong Zhou
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Esophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers with rapid progression and a high mortality rate. Our previous study demonstrated that DNA polymerase iota (Pol ι) is overexpressed in ESCC tumors and correlates with poor p
Externí odkaz:
https://doaj.org/article/87a5f708af6e45a1992db341e3fa460e
Autor:
Xueqi Yan, Jie Chen, You Meng, Chao He, Shitao Zou, Peng Li, Ming Chen, Jinchang Wu, Wei‐Qun Ding, Jundong Zhou
Publikováno v:
Cancer Medicine, Vol 8, Iss 6, Pp 3094-3104 (2019)
Abstract Neoadjuvant chemoradiotherapy (nCRT) has been widely applied to improve the local control rate and survival rate in patients with locally advanced rectal cancer (LARC), yet only part of LARC patients would benefit from nCRT. Therefore, it is
Externí odkaz:
https://doaj.org/article/7397f6c0cc514b248b034b655137e24a
Autor:
Bethany N. Hannafon, Angela Cai, Cameron L. Calloway, Yi-Fan Xu, Roy Zhang, Kar-Ming Fung, Wei-Qun Ding
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Altered expression of microRNAs (miRNAs) is known to contribute to cancer progression. miR-23b and miR-27b, encoded within the same miRNA cluster, are reported to have both tumor suppressive and oncogenic activity across human can
Externí odkaz:
https://doaj.org/article/1bda0b8a0f424485aee03fc8a7a2d00b
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Exosomes are small membrane-bound vesicles that contribute to tumor progression and metastasis by mediating cell-to-cell communication and modifying the tumor microenvironment at both local and distant sites. However, little is kn
Externí odkaz:
https://doaj.org/article/945bf7a95ade47a6883de1b6e2e619b1
Autor:
Yi-Fan Xu, Xiaohui Xu, Kritisha Bhandari, Amy Gin, Chinthalapally V. Rao, Katherine T. Morris, Bethany N. Hannafon, Wei-Qun Ding
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
microRNAs (miRNA) in extracellular vesicles (EVs) have been investigated as potential biomarkers for pancreatic ductal adenocarcinoma (PDAC). However, a mixed population of EVs is often obtained using conventional exosome isolation methods for biomar
Externí odkaz:
https://doaj.org/article/eeed02844ca04627b741dc99e144ab3d