Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Wei‐Chu Xu"'
Autor:
Nguyen, Han P. Q., Nhu Le, Doran, Emily, Polak, Emma, Andreatta, Jeremy, Kerr, Margaret, Wei-Chu Xu
Publikováno v:
Currents in Teaching & Learning; Sep2022, Vol. 14 Issue 1, p47-54, 8p
Autor:
Kai Huang, Nhu Le, Justin S. Wang, Ling Huang, Le Zeng, Wei‐Chu Xu, Zhanjun Li, Yang Li, Gang Han
Publikováno v:
Advanced Materials. 34:2107962
Persistent luminescence is a unique optical process where long-lasting afterglow persists after the cessation of excitation. Nanoscale persistent luminescent materials are getting increased research interest from various fields due to their unique op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::829cc47e1b8329e3cccbd78edb46d5d0
https://doi.org/10.1002/adma.202107962
https://doi.org/10.1002/adma.202107962
Publikováno v:
Bioorganicmedicinal chemistry. 27(15)
Despite the growing global crisis caused by antimicrobial drug resistance among pathogenic bacteria, the number of new antibiotics, especially new chemical class of antibiotics under development is insufficient to tackle the problem. Our review focus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e8bf3182e9ba2e69ae0518f370abb59
https://pubmed.ncbi.nlm.nih.gov/31221610
https://pubmed.ncbi.nlm.nih.gov/31221610
Publikováno v:
Letters in Organic Chemistry. 11:470-473
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01c74e3b746b43940d04e21255cf214d
https://doi.org/10.2174/1570178611666140219004433
https://doi.org/10.2174/1570178611666140219004433
Autor:
Wei-Chu Xu, Andrea Torti, Neal C. Brown, Andrea Lossani, George E. Wright, Lida Savi, Federico Focher
Publikováno v:
Current Enzyme Inhibition. 7:147-153
Based on the finding that aerobic Gram-positive antibacterials that inhibit DNA polymerase IIIC (pol IIIC) were potent inhibitors of the growth of anaerobic Clostridium difficile (CD) strains, we chose to clone and express the gene for pol IIIC from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1259ea97ed9bd2d55c53e3ff7b7e005
https://doi.org/10.2174/157340811798807597
https://doi.org/10.2174/157340811798807597
Autor:
Michelle M. Butler, Joseph Gambino, Neal C. Brown, Sofya Dvoskin, Zheng-yu Long, George E. Wright, Marjorie H. Barnes, Wei-Chu Xu, Chengxin Zhi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4197-4202
Several 2-anilino- and 2-benzylamino-3-deaza-6-oxopurines [3-deazaguanines] and selected 8-methyl and 8-aza analogs have been synthesized. 7-Substituted N2-(3-ethyl-4-methylphenyl)-3-deazaguanines were potent and selective inhibitors of Gram+ bacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec0380398f2183adc920068378ba90f
https://doi.org/10.1016/j.bmcl.2011.05.093
https://doi.org/10.1016/j.bmcl.2011.05.093
Autor:
Guo-Qiang Lin, Wei-Chu Xu
Publikováno v:
Chinese Journal of Chemistry. 13:380-384
Lipase catalyzed acetylation of 2 afforded 3 with the e.e. up to 98%. Utility of 3 was illustrated by the preparation of Prelog-Djerassi lactones 7a and 7b.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::380157c5e1776bfaf4931f64dc928197
https://doi.org/10.1002/cjoc.19950130414
https://doi.org/10.1002/cjoc.19950130414
Publikováno v:
Chinese Journal of Chemistry. 13:85-94
A facile enantioselective synthesis of all four stereoisomers of (2E,4E)-4,6,10,12-tetramethyl-2,4-tridecadien-7-one (1) is described. The stereochemistry at 6-C and 10-C of 1 was constructed by using optically active citronellal as starting material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3950902d8c83e04d86903a98d2dcbfd1
https://doi.org/10.1002/cjoc.19950130113
https://doi.org/10.1002/cjoc.19950130113
Autor:
Federico Focher, Milka Yanachkova, George E. Wright, Lida Savi, Timothy P. Foster, Edward J. Dix, M Dulfary Sanchez, Sofya Dvoskin, Wei-Chu Xu, Ivan B. Yanachkov
Publikováno v:
Antiviral chemistrychemotherapy. 24(2)
Background Because guanine-based herpes simplex virus thymidine kinase inhibitors are not orally available, we synthesized various 6-deoxy prodrugs of these compounds and evaluated them with regard to solubility in water, oral bioavailability, and ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::274728625846314ca7f50355b25cf80a
https://pubmed.ncbi.nlm.nih.gov/26463822
https://pubmed.ncbi.nlm.nih.gov/26463822
Autor:
George E. Wright, Zheng-yu Long, Marjorie H. Barnes, Michelle M. Butler, Chengxin Zhi, Joseph Gambino, Wei-Chu Xu, Neal C. Brown
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:729-732
7-Substituted-N(2)-(3,4-dichlorobenzyl)guanines potently and competitively inhibit DNA polymerases IIIC and IIIE from Gram(+) bacteria. Certain derivatives are also competitive inhibitors of DNA polymerase IIIE from Gram(-) bacteria.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4783294df115458ba9346baba8f84f95
https://doi.org/10.1016/j.bmcl.2004.11.016
https://doi.org/10.1016/j.bmcl.2004.11.016