Zobrazeno 1 - 10
of 305
pro vyhledávání: '"Wei‐Bang Guo"'
Autor:
Yang-Si Li, Wen-Pu Lai, Kai Yin, Mei-Mei Zheng, Hai-Yan Tu, Wei-Bang Guo, Liang Li, Shou-Heng Lin, Zhen Wang, Lu Zeng, Ben-Yuan Jiang, Zhi-Hong Chen, Qing Zhou, Xu-Chao Zhang, Jin-Ji Yang, Wen-Zhao Zhong, Xue-Ning Yang, Bin-Chao Wang, Yi Pan, Hua-Jun Chen, Fa-Man Xiao, Hao Sun, Yue-Li Sun, Xiao-Yan Bai, E.-E. Ke, Jia-Xin Lin, Si-Yang Maggie Liu, Yangqiu Li, Oscar Junhong Luo, Yi-Long Wu
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114613- (2024)
Summary: Leptomeningeal metastases (LMs) remain a devastating complication of non-small cell lung cancer (NSCLC), particularly following osimertinib resistance. We conducted single-cell RNA sequencing on cerebrospinal fluid (CSF) from EGFR-mutant NSC
Externí odkaz:
https://doaj.org/article/0665f6377f1241e58a85cf57da13bbbc
Autor:
Yu‐Min Zhong, Ji Chen, Jie Jiang, Wen‐Bin Zhou, Ling‐Ling Gao, Shui‐Lian Zhang, Wen‐Qing Yan, Yu Chen, Dong‐Kun Zhang, Dan‐Xia Lu, Zhi‐Yi Lv, Zhi Xie, Ying Huang, Wei‐Bang Guo, Bin‐Chao Wang, Jin‐Ji Yang, Xue‐Ning Yang, Yi‐Long Wu, Xu‐Chao Zhang
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Objectives Primary pulmonary lymphoepithelioma‐like carcinoma (PLELC) is a subtype of lung carcinoma associated with the Epstein–Barr virus (EBV). The clinical predictive biomarkers of immune checkpoint blockade (ICB) in PLELC require fu
Externí odkaz:
https://doaj.org/article/f6dc1728bee64dd9a6c7fb2fe41988fd
Autor:
Lin‐Lin Li, De‐Xiang Zhou, Ming Lu, Dong Zhou, Xiao‐Feng Lin, Yu Chen, Kai Yin, Hui‐Bo Feng, Wei‐Bang Guo, Zhi Xie, Wen‐Qing Yan, Zhi‐Yi Lv, Dan‐Xia Lu, Shui‐Lian Zhang, Xu‐Chao Zhang
Publikováno v:
Thoracic Cancer, Vol 13, Iss 13, Pp 1948-1960 (2022)
Abstract Background Brain metastases (BM) are common in lung cancer. However, data on the status of immune biomarkers in BM lesions remain limited. Methods We retrospectively analyzed PD‐L1 expression and infiltration levels of CD3+, CD4+, CD8+ T c
Externí odkaz:
https://doaj.org/article/96a76278b7814aa6900611b9fcddc7b7
Autor:
Zhen Wang, Xu-Chao Zhang, Wei-Neng Feng, Li Zhang, Xiao-Qing Liu, Wei-Bang Guo, Yan-Ming Deng, Qing-Feng Zou, Jin-Ji Yang, Qing Zhou, Bin-Chao Wang, Hua-Jun Chen, Hai-Yan Tu, Hong-Hong Yan, Yi-Long Wu
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Circulating tumor cells (CTCs) are prognostic biomarker in non-small-cell lung cancer (NSCLC). CTCs could also be used as predictor of efficacy of systemic treatments in advanced NSCLC. Objectives: We described the dynamic changes of CTCs
Externí odkaz:
https://doaj.org/article/3d41e67e02a8435983d78956b0f52623
Autor:
Hui‐Bo Feng, Yu Chen, Zhi Xie, Jie Jiang, Yu‐Min Zhong, Wei‐Bang Guo, Wen‐Qing Yan, Zhi‐Yi Lv, Dan‐Xia Lu, Hong‐Ling Liang, Fang‐Ping Xu, Jin‐Ji Yang, Xue‐Ning Yang, Qing Zhou, Dong‐Kun Zhang, Zhou Zhang, Shao‐Kun Chuai, Heng‐Hui Zhang, Yi‐Long Wu, Xu‐Chao Zhang
Publikováno v:
Thoracic Cancer, Vol 12, Iss 19, Pp 2564-2573 (2021)
Abstract Background Src homology region 2 domain‐containing phosphatase 2 (SHP2) is a novel target for Kirsten rat sarcoma oncogene (KRAS) mutant cancer. We retrospectively studied the significance of SHP2 in KRAS mutant non‐small cell lung cance
Externí odkaz:
https://doaj.org/article/be1a8728781c4fc394d58581ae7ef6be
Autor:
Kai Yin, Hui‐Bo Feng, Lin‐Lin Li, Yu Chen, Zhi Xie, Zhi‐Yi Lv, Wei‐Bang Guo, Dan‐Xia Lu, Xue‐Ning Yang, Wen‐Qing Yan, Yi‐Long Wu, Xu‐Chao Zhang
Publikováno v:
Thoracic Cancer, Vol 11, Iss 2, Pp 346-352 (2020)
Abstract Background Primary pulmonary lymphoepithelioma‐like carcinoma (PLELC) is a rare and unique subtype of lung cancer. However, the prevalence of driver alterations, such as epidermal growth factor receptor (EGFR) mutations and anaplastic lymp
Externí odkaz:
https://doaj.org/article/e4e7cbc8ccd4460783c53bd2c8389899
Autor:
Rui-Lian Chen, Jun Zhao, Xu-Chao Zhang, Na-Na Lou, Hua-Jun Chen, Xue Yang, Jian Su, Zhi Xie, Qing Zhou, Hai-Yan Tu, Wen-Zhao Zhong, Hong-Hong Yan, Wei-Bang Guo, Yi-Long Wu, Jin-Ji Yang
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Objective Crizotinib can target against mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK), which has been considered as a multi-targeted tyrosine kinase inhibitor (TKI). The objective of this study was to explore t
Externí odkaz:
https://doaj.org/article/337301170f914a0db4e9a863aa6e21ab
Autor:
Hong-Xia Tian, Xu-Chao Zhang, Zhen Wang, Jin-Ji Yang, Wei-Bang Guo, Zhi-Hong Chen, Yi-Long Wu
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 12, Pp 1446-1453 (2017)
Background: Drug resistance to targeted therapies occurs in lung cancer, and resistance mechanisms related to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are continuously being discovered. We aimed to establish a novel m
Externí odkaz:
https://doaj.org/article/c14f5df97e7d4e04a6a541562b837a54
Autor:
Hong-Xia Tian, Xu-Chao Zhang, Zhen Wang, Jian-Guang Chen, Shi-Liang Chen, Wei-Bang Guo, Yi-Long Wu
Publikováno v:
Cancer Biology & Medicine, Vol 13, Iss 1, Pp 68-76 (2016)
Objective: This study aims to establish a method for highly parallel multiplexed detection of genetic mutations in Chinese lung cancer samples through Agena iPLEX chemistry and matrix-assisted laser desorption ionization time-of-flight analysis on Ma
Externí odkaz:
https://doaj.org/article/4f7b3ead94694ceab53734db996033a1
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