Integrated Analysis of Patient Networks and Plasmid Genomes to Investigate a Regional, Multispecies Outbreak of Carbapenemase-Producing Enterobacterales Carrying Both blaIMP and mcr-9 Genes.

Autor: Wan Y; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom., Myall AC; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Department of Mathematics, Imperial College London, London, United Kingdom., Boonyasiri A; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Bolt F; Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom.; Centre for Antimicrobial Optimisation, Hammersmith Hospital, Imperial College London, London, United Kingdom.; Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom., Ledda A; Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom.; HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, United Kingdom., Mookerjee S; Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom., Weiße AY; School of Biological Sciences, University of Edinburgh, Scotland, United Kingdom.; School of Informatics, University of Edinburgh, Scotland, United Kingdom., Getino M; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom., Turton JF; HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, United Kingdom., Abbas H; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Department of Microbiology, North West London Pathology, London, United Kingdom., Prakapaite R; MRC Centre for Molecular Bacteriology and Infection, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Sabnis A; MRC Centre for Molecular Bacteriology and Infection, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Abdolrasouli A; Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom., Malpartida-Cardenas K; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Centre for Bio-Inspired Technology, Department of Electrical and Electronic Engineering, Faculty of Engineering, Imperial College London, London, United Kingdom., Miglietta L; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Centre for Bio-Inspired Technology, Department of Electrical and Electronic Engineering, Faculty of Engineering, Imperial College London, London, United Kingdom., Donaldson H; Department of Microbiology, North West London Pathology, London, United Kingdom., Gilchrist M; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom., Hopkins KL; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, United Kingdom., Ellington MJ; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Reference Services Division, UK Health Security Agency, London, United Kingdom., Otter JA; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom., Larrouy-Maumus G; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; MRC Centre for Molecular Bacteriology and Infection, Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London, United Kingdom., Edwards AM; MRC Centre for Molecular Bacteriology and Infection, Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, United Kingdom., Rodriguez-Manzano J; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Centre for Antimicrobial Optimisation, Hammersmith Hospital, Imperial College London, London, United Kingdom.; Centre for Bio-Inspired Technology, Department of Electrical and Electronic Engineering, Faculty of Engineering, Imperial College London, London, United Kingdom., Didelot X; School of Life Sciences and Department of Statistics, University of Warwick, Coventry, United Kingdom., Barahona M; Department of Mathematics, Imperial College London, London, United Kingdom., Holmes AH; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom.; Centre for Antimicrobial Optimisation, Hammersmith Hospital, Imperial College London, London, United Kingdom., Jauneikaite E; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Department of Infectious Disease Epidemiology, School of Public Health, Imperial College London, London, United Kingdom., Davies F; NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Department of Infectious Disease, Imperial College London, London, United Kingdom.; Department of Infectious Diseases, Imperial College Healthcare NHS Trust, London, United Kingdom.; Department of Microbiology, North West London Pathology, London, United Kingdom.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2024 Jul 25; Vol. 230 (1), pp. e159-e170.

Prediction of hospital-onset COVID-19 infections using dynamic networks of patient contact: an international retrospective cohort study.

Autor: Myall A; Department of Infectious Disease, Imperial College London, London, UK; Department of Mathematics, Imperial College London, London, UK; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK. Electronic address: a.myall19@imperial.ac.uk., Price JR; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK; Imperial College Healthcare NHS Trust, Imperial College London, London, UK., Peach RL; Department of Mathematics, Imperial College London, London, UK; Department of Brain Sciences, Imperial College London, London, UK; Department of Neurology, University Hospital of Würzburg, Würzburg, Germany., Abbas M; MRC Centre for Global Infectious Disease Analysis, Imperial College London, London, UK; Infection Control Programme, Geneva University Hospitals, Geneva, Switzerland., Mookerjee S; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK; Imperial College Healthcare NHS Trust, Imperial College London, London, UK., Zhu N; Department of Infectious Disease, Imperial College London, London, UK; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK., Ahmad I; Department of Infectious Disease, Imperial College London, London, UK; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK., Ming D; Department of Infectious Disease, Imperial College London, London, UK; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK., Ramzan F; Department of Infectious Disease, Imperial College London, London, UK; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK., Teixeira D; Infection Control Programme, Geneva University Hospitals, Geneva, Switzerland., Graf C; Department of Rehabilitation and Geriatrics, Geneva University Hospitals, Geneva, Switzerland., Weiße AY; School of Biological Sciences and School of Informatics, University of Edinburgh, Edinburgh, UK., Harbarth S; Infection Control Programme, Geneva University Hospitals, Geneva, Switzerland., Holmes A; Department of Infectious Disease, Imperial College London, London, UK; National Institute for Health Research Health Protection Research Unit in HCAI and AMR, Imperial College London, London, UK., Barahona M; Department of Mathematics, Imperial College London, London, UK. Electronic address: m.barahona@imperial.ac.uk.

Publikováno v: The Lancet. Digital health [Lancet Digit Health] 2022 Aug; Vol. 4 (8), pp. e573-e583.

Informing antimicrobial management in the context of COVID-19: understanding the longitudinal dynamics of C-reactive protein and procalcitonin.

Autor: Ming DK; Centre for Antimicrobial Optimisation, Hammersmith Hospital, Imperial College London, Du Cane Road, London, W12 0NN, UK. d.ming@imperial.ac.uk.; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK. d.ming@imperial.ac.uk., Myall AC; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.; Department of Mathematics, Imperial College London, London, UK., Hernandez B; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK., Weiße AY; School of Informatics, University of Edinburgh, Scotland, UK.; School of Biological Science, University of Edinburgh, Scotland, UK., Peach RL; Department of Neurology, University Hospital of Würzburg, 97080, Würzburg, Germany.; Department of Mathematics, Imperial College London, London, UK., Barahona M; Department of Mathematics, Imperial College London, London, UK., Rawson TM; Centre for Antimicrobial Optimisation, Hammersmith Hospital, Imperial College London, Du Cane Road, London, W12 0NN, UK.; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK., Holmes AH; Centre for Antimicrobial Optimisation, Hammersmith Hospital, Imperial College London, Du Cane Road, London, W12 0NN, UK.; National Institute for Health Research Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance, Imperial College London, Hammersmith Campus, Du Cane Road, London, W12 0NN, UK.

Publikováno v: BMC infectious diseases [BMC Infect Dis] 2021 Sep 08; Vol. 21 (1), pp. 932. Date of Electronic Publication: 2021 Sep 08.

Prediction of Cellular Burden with Host-Circuit Models.

Autor: Nikolados EM; School of Biological Sciences, University of Edinburgh, Edinburgh, UK., Weiße AY; School of Informatics, University of Edinburgh, Edinburgh, UK., Oyarzún DA; School of Biological Sciences, University of Edinburgh, Edinburgh, UK. d.oyarzun@ed.ac.uk.; School of Informatics, University of Edinburgh, Edinburgh, UK. d.oyarzun@ed.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2229, pp. 267-291.

Growth Defects and Loss-of-Function in Synthetic Gene Circuits.

Autor: Nikolados EM; School of Biological Sciences , University of Edinburgh , Edinburgh EH9 3BF , United Kingdom., Weiße AY; Department of Medicine , Imperial College London, Hammersmith Hospital , London W12 0NN , United Kingdom., Ceroni F; Department of Chemical Engineering , Imperial College London , London SW7 2AZ , United Kingdom.; Imperial College Centre for Synthetic Biology , Imperial College London , London SW7 2AZ , United Kingdom., Oyarzún DA; School of Biological Sciences , University of Edinburgh , Edinburgh EH9 3BF , United Kingdom.; School of Informatics , University of Edinburgh , Edinburgh EH8 9AB , United Kingdom.; SynthSys - Centre for Synthetic & Systems Biology , University of Edinburgh , Edinburgh EH9 3BF , United Kingdom.

Publikováno v: ACS synthetic biology [ACS Synth Biol] 2019 Jun 21; Vol. 8 (6), pp. 1231-1240. Date of Electronic Publication: 2019 Jun 04.