Výsledky vyhledávání - "Weena J.Y. Chen"

Effects of exenatide on cardiac function, perfusion, and energetics in type 2 diabetic patients with cardiomyopathy: a randomized controlled trial against insulin glargine

Autor: Weena J.Y. Chen, Hendrik J. Harms, Paul Knaapen, Lourens Robbers, Adriaan A. Lammertsma, Mark H. H. Kramer, Albert C. van Rossum, Karin de Boer, Michaela Diamant

Publikováno v: Cardiovascular Diabetology
Cardiovascular Diabetology, Vol 16, Iss 1, Pp 1-12 (2017)
Cardiovascular Diabetology, 16:67. BioMed Central
Chen, W J Y, Diamant, M, de Boer, K, Harms, H J, Robbers, L F H J, van Rossum, A C, Kramer, M H H, Lammertsma, A A & Knaapen, P 2017, ' Effects of exenatide on cardiac function, perfusion, and energetics in type 2 diabetic patients with cardiomyopathy: a randomized controlled trial against insulin glargine ', Cardiovascular Diabetology, vol. 16, 67 . https://doi.org/10.1186/s12933-017-0549-z

Background Multiple bloodglucose-lowering agents have been linked to cardiovascular events. Preliminary studies showed improvement in left ventricular (LV) function during glucagon-like peptide-1 receptor agonist administration. Underlying mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821f6489f4c8611df74fc8cb08ab905e
https://pubmed.ncbi.nlm.nih.gov/28526033

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Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction

Autor: Flip J.P. Bernink, Weena J.Y. Chen, Leo Timmers, Anton J.G. Horrevoets, Michaela Diamant, Cansu Yıldırım, J.M. Baggen, Pieter Koolwijk, Tineke C. T. M. van der Pouw Kraan, Niels van Royen, Albert C. van Rossum, Yolande Appelman, Aernout M. Beek

Publikováno v: Journal of Molecular and Cellular Cardiology, 67, 94-102. Academic Press Inc.
van der Pouw Kraan, C T M, Bernink, F J P, Yildirim, C, Koolwijk, P, Baggen, J M, Timmers, L, Beek, A M, Diamant, M, Chen, W J Y, van Rossum, A C, van Royen, N, Horrevoets, A J G & Appelman, J E A 2014, ' Systemic toll-like receptor and interleukin-18 pathway activation in patients with acute ST elevation myocardial infarction ', Journal of Molecular and Cellular Cardiology, vol. 67, pp. 94-102 . https://doi.org/10.1016/j.yjmcc.2013.12.021

Acute myocardial infarction (AMI) is accompanied by increased expression of Toll like receptors (TLR)-2 and TLR4 on circulating monocytes. In animal models, blocking TLR2/4 signaling reduces inflammatory cell influx and infarct size. The clinical con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569d4be5377e9574f15a51d69a969f0c
https://doi.org/10.1016/j.yjmcc.2013.12.021

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Effect of Type 2 Diabetes Mellitus on Epicardial Adipose Tissue Volume and Coronary Vasomotor Function

Autor: Michaela Diamant, Weena J.Y. Chen, Adriaan A. Lammertsma, Pieter G. Raijmakers, Hendrik J. Harms, Albert C. van Rossum, Ibrahim Danad, Paul Knaapen, Rick Halbmeijer

Publikováno v: Chen, J Y, Danad, I, Raijmakers, P G, Halbmeijer, R, Harms, H J, Lammertsma, A A, van Rossum, A C, Diamant, M & Knaapen, P 2014, ' Effect of Type 2 Diabetes Mellitus on Epicardial Adipose Tissue Volume and Coronary Vasomotor Function ', American Journal of Cardiology, vol. 113, no. 1, pp. 90-97 . https://doi.org/10.1016/j.amjcard.2013.09.022
American Journal of Cardiology, 113(1), 90-97. Elsevier Inc.

Patients with coronary artery disease and/or type 2 diabetes mellitus (DM) generally exhibit more epicardial adipose tissue (EAT) than healthy controls. Recently, it has been proposed that EAT affects vascular function and structure by secreting proi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623aa9a31fa0e55d0f212a04859edfd6
https://doi.org/10.1016/j.amjcard.2013.09.022

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Palmitic acid increases pro-oxidant adaptor protein p66Shc expression and affects vascularization factors in angiogenic mononuclear cells: Action of resveratrol

Autor: Pieter Koolwijk, Erik H. Serné, René J. P. Musters, Juan-Jesus Garcia-Vallejo, J.M. Baggen, Tineke C. T. M. van der Pouw Kraan, Anton J.G. Horrevoets, Weena J.Y. Chen, Larissa W. van Golen, Thomas A. Leyen, Michaela Diamant, Ruud D. Fontijn, Renate E. van Genugten, Julie Favre, Cansu Yıldırım

Publikováno v: Favre, J, Yildirim, C, Leyen, T A, Chen, J Y, van Genugten, R E, van Golen, L W, Garcia Vallejo, J J, Musters, R J P, Baggen, J M, Fontijn, R D, van der Pouw-Kraan, T C T M, Serne, E H, Koolwijk, P, Diamant, M & Horrevoets, A J 2015, ' Palmitic acid increases pro-oxidant adaptor protein p66Shc expression and affects vascularization factors in angiogenic mononuclear cells: Action of resveratrol ', Vascular Pharmacology, vol. 75, pp. 7-18 . https://doi.org/10.1016/j.vph.2015.08.003
Vascular Pharmacology, 75, 7-18. Elsevier Inc.

A defect in neo-vascularization process involving circulating angiogenic mononuclear cells (CACs) dysfunction is associated with diabetes. We showed that oxidative stress was elevated in CACs cultured from blood of individuals with metabolic syndrome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea52863d33be45f816c310ebf7761843
https://pubmed.ncbi.nlm.nih.gov/26254104

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Metabolic changes in type 2 diabetes are reflected in peripheral blood cells, revealing aberrant cytotoxicity, a viral signature, and hypoxia inducible factor activity

Autor: Mathijs C. Bunck, Nynke J. van der Zijl, Weena J.Y. Chen, Renate E. van Genugten, Erik H. Serné, Anton J.G. Horrevoets, Daniël H. van Raalte, J.M. Baggen, Liselotte van Bloemendaal, Tineke C. T. M. van der Pouw Kraan, Michaela Diamant

Publikováno v: BMC Medical Genomics
van der Pouw-Kraan, T C T M, Chen, J Y, Bunck, M C M, van Raalte, D H, van der Zijl, N J, van Genugten, R E, van Bloemendaal, L, Baggen, J M, Serne, E H, Diamant, M & Horrevoets, A J G 2015, ' Metabolic changes in type 2 diabetes are reflected in peripheral blood cells, revealing aberrant cytotoxicity, a viral signature, and hypoxia inducible factor activity ', BMC Medical Genomics, vol. 8, 20 . https://doi.org/10.1186/s12920-015-0096-y
BMC Medical Genomics, 8:20. BioMed Central

Background Metabolic syndrome (MetS) is characterized by central obesity, insulin resistance, dysglycemia, and a pro-atherogenic plasma lipid profile. MetS creates a high risk for development of type 2 diabetes (T2DM) and cardiovascular disease (CVD)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123f36ba59af6062da95d4e4d37fbada
https://doi.org/10.1186/s12920-015-0096-y

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Rolle des Adipokins CD14 bei der Entstehung einer kardiovaskulären Dysfunktion

Autor: Konstantinos Smiris, Michaela Diamant, H Müller, Ouwens, A. Lichtenberg, Bujar Maxhera, D Herzfeld de Wiza, Sabrina Greulich, Marcel Blumensatt, Weena J.Y. Chen

Publikováno v: Diabetologie und Stoffwechsel. 9

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::391c1a26dbf0b9b5e24167732df8d215
https://doi.org/10.1055/s-0034-1374904

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Activin a is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes

Autor: Luuk J. Rijzewijk, Hildo J. Lamb, Johannes A. Romijn, Rutger W. van der Meer, Johannes W. A. Smit, Mark Lubberink, Weena J.Y. Chen, Albert de Roos, Johannes Ruige, Michaela Diamant, D. Margriet Ouwens, Adriaan A. Lammertsma, Sabrina Greulich

Publikováno v: Cardiovascular Diabetology, 12
Cardiovascular Diabetology
Cardiovascular diabetology, 12(1). BioMed Central
Cardiovascular Diabetology, 12:150. BioMed Central
Chen, W J Y, Greulich, S, van der Meer, R W, Rijzewijk, L J, Lamb, H J, de Roos, A, Smit, J W A, Romijn, J A, Ruige, J B, Lammertsma, A A, Lubberink, M, Diamant, M & Ouwens, D M 2013, ' Activin a is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes ', Cardiovascular Diabetology, vol. 12, 150 . https://doi.org/10.1186/1475-2840-12-150

Background Activin A released from epicardial adipose tissue has been linked to contractile dysfunction and insulin resistance in cardiomyocytes. This study investigated the role of activin A in clinical diabetic cardiomyopathy by assessing whether c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad49b475f02a59cfdd7a2451ed69b87f
https://hdl.handle.net/1887/100227

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Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: The EXAMI study

Autor: Weena J.Y. Chen, Aernout M. Beek, Pieter A. Doevendans, Flip J.P. Bernink, Yolande Appelman, Leo Timmers, Niels van Royen, Otto Kamp, Martijn Scholte, Robert N. Denham, Koen M. Marques, Albert C. van Rossum, Michaela Diamant, Anton J.G. Horrevoets

Publikováno v: Bernink, F J P, Timmers, L, Diamant, M, Scholte, M, Beek, A M, Kamp, O, Marques, K M J, Denham, R N, Chen, W J Y, Doevendans, P A, van Rossum, A C, van Royen, N, Horrevoets, A J G & Appelman, J E A 2013, ' Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction: The EXAMI study ', International Journal of Cardiology, vol. 167, no. 1, pp. 289-290 . https://doi.org/10.1016/j.ijcard.2012.09.204
International Journal of Cardiology, 167(1), 289-290. Elsevier Ireland Ltd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5e0588f23e7bc1a9dfaf4efe565e20b
https://research.vumc.nl/en/publications/df03904e-8e0c-4da8-bb36-4a86cbe7c1ff

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Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies

Publikováno v: PLoS One, 8
PLoS ONE, Vol 8, Iss 3, p e59697 (2013)
PLoS ONE; Vol 8
Greulich, S, Chen, W J Y, Maxhera, B, Rijzewijk, L J, van der Meer, R W, Jonker, J T, Mueller, H, de Wiza, D H, Floerke, R R, Smiris, K, Lamb, H J, de Roos, A, Bax, J J, Romijn, J A, Smit, J W A, Akhyari, P, Lichtenberg, A, Eckel, J, Diamant, M & Ouwens, D M 2013, ' Cardioprotective Properties of Omentin-1 in Type 2 Diabetes: Evidence from Clinical and In Vitro Studies ', PLoS ONE, vol. 8, no. 3, e59697 . https://doi.org/10.1371/journal.pone.0059697
PLoS ONE
PLoS ONE, 8(3)
PLoS ONE, 8(3):e59697. Public Library of Science
PLoS One, 8, 3
PLoS ONE, 8(3). Public Library of Science

Contains fulltext : 118105.pdf (Publisher’s version ) (Open Access) CONTEXT: Adipokines are linked to the development of cardiovascular dysfunction in type 2 diabetes (DM2). In DM2-patients, circulating levels of omentin-1, an adipokine preferentia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90be8a9fd3eed2bb193b1996c2bfa772
https://doi.org/10.1371/journal.pone.0059697

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