New developments in the antiviral treatment of hepatitis C.

Autor: de Bruijne, J.¹ j.debruijne@amc.nl, Weegink, C. J.¹, Jansen, P. L. M.¹, Reesink, H. W.¹

Publikováno v: Vox Sanguinis. Jul2009, Vol. 97 Issue 1, p1-12. 12p. 2 Diagrams, 3 Charts.

Randomised clinical trial: anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV

Autor: Bergmann, J. F., de Bruijne, J., Hotho, D. M., de Knegt, R. J., Boonstra, A., Weegink, C. J., van Vliet, A. A., van de Wetering, J., Fletcher, S. P., Bauman, L. A., Rahimy, M., Appleman, J. R., Freddo, J. L., Janssen, H. L. A., Reesink, H. W.

Publikováno v: Alimentary Pharmacology & Therapeutics, 34(4), 443-453. Wiley-Blackwell Publishing Ltd
Alimentary pharmacology & therapeutics, 34(4), 443-453. Wiley-Blackwell

Background The ANA773 is an oral prodrug of a small-molecule toll-like receptor (TLR)7 agonist. Preclinical and healthy volunteer clinical studies with ANA773 have demonstrated induction of endogenous interferon-alpha (IFN-alpha) of multiple subtypes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8cfacd8924d9b277c639cd67cbc4b689
https://pure.eur.nl/en/publications/20bf8aaa-60b5-4317-94cf-7a771eeea9be

Hepatitis C in Nederland: schaarse gegevens over actuele prevalentie en de noodzaak van epidemiologisch onderzoek en innovatieve opsporingsmethoden

Autor: Kok, A., Zuure, F. R., Weegink, C. J., Coutinho, R. A., Prins, M. [= Maria]

Publikováno v: Nederlands tijdschrift voor geneeskunde, 151(43), 2367-2371. Bohn Stafleu van Loghum

Hepatitis C is a blood-borne virus infection with an estimated 180 million infected individuals worldwide. Hepatitis C virus (HCV) infection may lead to liver failure and cancer of the liver. In 2004, in view of the improved treatment options, the Du

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a95002339cc497b1c348abb0c699e470
https://pure.amc.nl/en/publications/hepatitis-c-in-nederland-schaarse-gegevens-over-actuele-prevalentie-en-de-noodzaak-van-epidemiologisch-onderzoek-en-innovatieve-opsporingsmethoden(96c7dd06-b7ec-487d-83bf-31004d6b03d7).html

Beleid bij acute hepatitis C en bij prikaccidenten met hepatitis-C-viruspositief bloed

Autor: Cooreman, M. P., Weegink, C., Reesink, H. W.

Publikováno v: Nederlands tijdschrift voor geneeskunde, 142(42), 2298-2300. Bohn Stafleu van Loghum

Acute hepatitis C is rarely diagnosed, in part because of its usually subclinical course. Infection with the hepatitis C virus (HCV) has a high chronicity rate, 70-90%. The risk of infection after a needlestick accident with HCV positive blood is 3-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::bd905f1e8c0a0f427272cf67332b19e3
https://pure.amc.nl/en/publications/beleid-bij-acute-hepatitis-c-en-bij-prikaccidenten-met-hepatitiscviruspositief-bloed(842fcb26-15f1-48eb-b2a7-de05ee6911ec).html

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