BRCA1 and p53 protein expression in cultured ovarian surface epithelial cells derived from women with and without a BRCA1 germline mutation

Autor: Piek, J.M., Dorsman, J.C., Massuger, L.F.A.G., Ansink, A.C., Weegenaar, J., Shvarts, A., Kenemans, P., Verheijen, R.H.

Publikováno v: Archives of Gynecology and Obstetrics, 274, 6, pp. 327-31
Archives of Gynecology and Obstetrics, 274, 327-31

Item does not contain fulltext AIM: Mutations in the BRCA1 and TP53 genes are early genetic events leading to (hereditary) ovarian carcinoma. The human ovarian surface epithelium (OSE) is considered the tissue of origin of at least a subset of these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c82062f828524065dc8aeca703e787a8
https://hdl.handle.net/2066/50862

Expression of differentiation and proliferation related proteins in epithelium of prophylactically removed ovaries from women with a hereditary female adnexal cancer predisposition

Autor: Piek, J M J, Verheijen, R H M, Menko, F H, Jongsma, A P M, Weegenaar, J, Gille, J J P, Pals, G, Kenemans, P, van Diest, P J

Publikováno v: Histopathology, 43(1), 26-32. Wiley-Blackwell
Piek, J M J, Verheijen, R H M, Menko, F H, Jongsma, A P M, Weegenaar, J, Gille, J J P, Pals, G, Kenemans, P & van Diest, P J 2003, ' Expression of differentiation and proliferation related proteins in epithelium of prophylactically removed ovaries from women with a hereditary female adnexal cancer predisposition ', Histopathology, vol. 43, no. 1, pp. 26-32 .

AIMS: To investigate the occurrence of preinvasive neoplastic lesions in ovarian surface epithelium and ovarian inclusion cyst epithelium of women with a hereditary predisposition to the development of female adnexal (ovarian and fallopian tube) carc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a20968b41b341c711a311e6ff313cc05
https://research.vumc.nl/en/publications/5b9bcff8-d3ce-4e99-9600-b40ec4fbe9b9

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