Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wee Siang Teo"'
Autor:
Simon Brayford, Alastair Duly, Wee Siang Teo, Tanya Dwarte, Estrella Gonzales‐Aloy, Zerong Ma, Laura McVeigh, Timothy W. Failes, Greg M. Arndt, Joshua A. McCarroll, Maria Kavallaris
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 4455-4471 (2023)
Abstract Non‐Small Cell Lung Carcinoma (NSCLC) remains a leading cause of cancer death. Resistance to therapy is a significant problem, highlighting the need to find new ways of sensitising tumour cells to therapeutic agents. βIII‐tubulin is ass
Externí odkaz:
https://doaj.org/article/ca6480afb088470ca3e0c2a36817e4bf
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Microtubule proteins form a dynamic component of the cytoskeleton, and play key roles in cellular processes, such as vesicular transport, cell motility and mitosis. Expression of microtubule proteins are often dysregulated in cancer. In particular, t
Externí odkaz:
https://doaj.org/article/38fd23ec7eff4478ac9ab6e135d724f6
Autor:
Amelia L. Parker, Wee Siang Teo, Simon Brayford, Ullhas K. Moorthi, Senthil Arumugam, Charles Ferguson, Robert G. Parton, Joshua A. McCarroll, Maria Kavallaris
Publikováno v:
Cells, Vol 11, Iss 5, p 776 (2022)
βIII-tubulin is a neuronal microtubule protein that is aberrantly expressed in epithelial cancers. The microtubule network is implicated in regulating the architecture and dynamics of the mitochondrial network, although the isotype-specific role for
Externí odkaz:
https://doaj.org/article/8e2982ef91314d80a96294902b9f259a
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 7, p 1434 (2017)
Tubulin proteins, as components of the microtubule cytoskeleton perform critical cellular functions throughout all phases of the cell cycle. Altered tubulin isotype composition of microtubules is emerging as a feature of aggressive and treatment refr
Externí odkaz:
https://doaj.org/article/a62c7aa6bde64ad9b35eab4d7b8bf5d7
Autor:
Simon Brayford, Alastair Duly, Wee Siang Teo, Tanya Dwarte, Estrella Gonzales‐Aloy, Zerong Ma, Laura McVeigh, Timothy W. Failes, Greg M. Arndt, Joshua A. McCarroll, Maria Kavallaris
Publikováno v:
Cancer medicineREFERENCES.
Non-Small Cell Lung Carcinoma (NSCLC) remains a leading cause of cancer death. Resistance to therapy is a significant problem, highlighting the need to find new ways of sensitising tumour cells to therapeutic agents. βIII-tubulin is associated with
Autor:
Parker, Amelia L.1,2 aparker@ccia.unsw.edu.au, Wee Siang Teo1,2 wteo@ccia.unsw.edu.au, McCarroll, Joshua A.1,2 Jmccarroll@ccia.unsw.edu.au, Kavallaris, Maria1,2 m.kavallaris@ccia.unsw.edu.au
Publikováno v:
International Journal of Molecular Sciences. Jul2017, Vol. 18 Issue 7, p1434. 24p. 1 Diagram, 1 Chart.
Autor:
Jason T. George, Wee Siang Teo, Aurélie Cazet, Alexander Swarbrick, Andrea McFarland, Daniel L. Roden, Christina Valbirk Konrad, Eoin Dodson, P T Archana, Radhika Nair, Reshma Murali, Mohit Kumar Jolly, Herbert Levine, Binitha Anu Varghese, Nitheesh Karthikeyan, Holly Holliday
Evidence points to breast cancer following a hierarchical model, with Cancer Stem Cells (CSCs) driving critical phenotypes of the bulk tumor. Chemoresistant CSCs are not an abstract concept but have clinical consequences as they drive relapse and ult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518c5156b41d147f34d150a339377730
https://doi.org/10.1101/760686
https://doi.org/10.1101/760686
Autor:
Iva Nikolic, Sunil R. Lakhani, Alexander Swarbrick, Jessica Yang, Nitheesh Karthikeyan, Christopher J. Ormandy, Binitha Anu Varghese, Holly Holliday, Andrea McFarland, Chia-Ling Chan, Warren Kaplan, P T Archana, Sunny Ye, Simon Junankar, Mathew J. Naylor, Christina Valbirk Konrad, Daniel L. Roden, Laura A. Baker, Albert S. Mellick, Jaynish S. Shah, Sandra A O'Toole, Wee Siang Teo, Ewan K.A. Millar, Reshma Murali, Aurélie Cazet, Kate Harvey, Radhika Nair
Background Breast cancers display phenotypic and functional heterogeneity. Several lines of evidence support the existence of cancer stem cells (CSCs) in certain breast cancers, a minor population of cells capable of tumor initiation and metastatic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d605abe7ee9f1a62105742b15e0b54c3
Autor:
Alexander Swarbrick, Jessica Yang, Binitha Anu Varghese, Mohit Kumar Jolly, Herbert Levine, Wee Siang Teo, Reshma Murali, Christina Valbirk Konrad, Radhika Nair, Archana P. Thankamony, Nitheesh Karthikeyan, Holly Holliday, Daniel L. Roden, Eoin Dodson, Aurélie Cazet, Laura A. Baker, Andrea McFarland, Jason T. George
Publikováno v:
Biomolecules
Volume 10
Issue 9
Biomolecules, Vol 10, Iss 1295, p 1295 (2020)
Volume 10
Issue 9
Biomolecules, Vol 10, Iss 1295, p 1295 (2020)
The basic helix-loop-helix (bHLH) transcription factors inhibitor of differentiation 1 (Id1) and inhibitor of differentiation 3 (Id3) (referred to as Id) have an important role in maintaining the cancer stem cell (CSC) phenotype in the triple-negativ