Targeting non-canonical pathways as a strategy to modulate the sodium iodide symporter.

Autor: Read ML; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Brookes K; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Thornton CEM; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Fletcher A; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Nieto HR; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Alshahrani M; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Khan R; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Borges de Souza P; Section of Endocrinology, Department of Medical Sciences, University of Ferrara, Ferrara 44124, Italy., Zha L; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., Webster JRM; Protein Expression Facility, College of Medical and Dental Sciences, University of Birmingham, B15 2TT, UK., Alderwick LJ; Birmingham Drug Discovery Facility, School of Biosciences, University of Birmingham, Birmingham B15 2TT, UK., Campbell MJ; Division of Pharmaceutics and Pharmacology, The Ohio State University, College of Pharmacy, Columbus, OH 43210, USA., Boelaert K; Institute of Applied Health Research, University of Birmingham, Birmingham B15 2TT, UK., Smith VE; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK., McCabe CJ; Institute of Metabolism and Systems Research (IMSR), and Centre of Endocrinology, Diabetes and Metabolism (CEDAM), University of Birmingham, Birmingham B15 2TT, UK. Electronic address: mccabcjz@bham.ac.uk.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2022 Mar 17; Vol. 29 (3), pp. 502-516.e7. Date of Electronic Publication: 2021 Sep 13.