Zobrazeno 1 - 10
of 579
pro vyhledávání: '"Web Server issue"'
Autor:
Brad T Sherman, Ming Hao, Ju Qiu, Xiaoli Jiao, Michael W Baseler, H Clifford Lane, Tomozumi Imamichi, Weizhong Chang
Publikováno v:
Nucleic Acids Res
DAVID is a popular bioinformatics resource system including a web server and web service for functional annotation and enrichment analyses of gene lists. It consists of a comprehensive knowledgebase and a set of functional analysis tools. Here, we re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df1ffbfd34fe96eddcbe86d67b5b2cd1
https://doi.org/10.1093/nar/gkac194
https://doi.org/10.1093/nar/gkac194
Autor:
Rika Maruyama, William Duddy, Narin Sheri, Omar Sheikh, Shuntaro Chiba, Stanley Woo, Esra J N Erkut, Saeed Anwar, Katsuhiko Kunitake, Tejal Aslesh, Yasushi Okuno, Nur Ahad Shah, Toshifumi Yokota, Kenji Rowel Q. Lim, Hiroaki Takano, Yoshitsugu Aoki
Publikováno v:
Nucleic Acids Research
Exon skipping using antisense oligonucleotides (ASOs) has recently proven to be a powerful tool for mRNA splicing modulation. Several exon-skipping ASOs have been approved to treat genetic diseases worldwide. However, a significant challenge is the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a7af91e7beb693ca290bf9c2edfb7ca
https://doi.org/10.1093/nar/gkab442
https://doi.org/10.1093/nar/gkab442
Autor:
Nathaniel Goodman, Norbert Perrimon, Erica Larschan, Charles E. Lawrence, Yanhui Hu, Ashley M Conard, Ritambhara Singh
Publikováno v:
Nucleic Acids Research
Uncovering how transcription factors regulate their targets at DNA, RNA and protein levels over time is critical to define gene regulatory networks (GRNs) and assign mechanisms in normal and diseased states. RNA-seq is a standard method measuring gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21243419efde5dbb1d1020d565ccbeb
http://europepmc.org/articles/PMC8262710
http://europepmc.org/articles/PMC8262710
Autor:
Ivo C Leist, Robert B. Russell, Kyle R Weise, Mustafa F R Ibrahim, Juan Carlos González-Sánchez
Publikováno v:
Nucleic Acids Research
Advances in DNA sequencing and proteomics mean that researchers must now regularly interrogate thousands of positional gene/protein changes in order to find those relevant for potential clinical application or biological insights. The abundance of al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a8a39e66e40f0a963fba8bd78f6eac
http://europepmc.org/articles/PMC8262711
http://europepmc.org/articles/PMC8262711
Publikováno v:
Nucleic Acids Research
We present an updated version of the Voronoia service that enables fully automated analysis of the atomic packing density of macromolecules. Voronoia combines previous efforts to analyse 3D protein and RNA structures into a single service, combined w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::debee76d13a3c16b0500361e91202bd0
http://europepmc.org/articles/PMC8265189
http://europepmc.org/articles/PMC8265189
Publikováno v:
Nucleic Acids Research
In 2017, we released GEPIA (Gene Expression Profiling Interactive Analysis) webserver to facilitate the widely used analyses based on the bulk gene expression datasets in the TCGA and the GTEx projects, providing the biologists and clinicians with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe870e5ba25166dabbf2094b5c963c6
https://doi.org/10.1093/nar/gkab418
https://doi.org/10.1093/nar/gkab418
Publikováno v:
Nucleic Acids Research
Protein–protein interactions play crucial roles in diverse biological processes, including various disease progressions. Atomistic structural details of protein–protein interactions may provide important information that can facilitate the design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3f1dd53dbd6704366bed2b3a539f16
https://doi.org/10.1093/nar/gkab422
https://doi.org/10.1093/nar/gkab422
Autor:
Jessica Ding, Xia Yang, Thien Xuan Nghiem, Sung-Min Ha, Gaoyan Li, Montgomery Blencowe, Yen-Wei Chen
Publikováno v:
Nucleic Acids Research
The Mergeomics web server is a flexible online tool for multi-omics data integration to derive biological pathways, networks, and key drivers important to disease pathogenesis and is based on the open source Mergeomics R package. The web server takes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97bb02e7e690328e01058ade7bd4ac4c
https://doi.org/10.1093/nar/gkab405
https://doi.org/10.1093/nar/gkab405
Publikováno v:
Nucleic Acids Research
High-throughput cell proliferation assays to quantify drug-response are becoming increasingly common and powerful with the emergence of improved automation and multi-time point analysis methods. However, pipelines for analysis of these datasets that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee860e101172bbdd391314f4fe4fe8c
https://doi.org/10.1093/nar/gkab424
https://doi.org/10.1093/nar/gkab424
Autor:
Thomas Guignard, Audrey Schalk, Jean-Baptiste Gaillard, Hélène Dollfus, Tor Solli-Nowlan, Véronique Geoffroy, Arnaud Kress, Vincent Gatinois, Sophie Scheidecker, Jean Muller
Publikováno v:
Nucleic Acids Research
Nucleic Acids Research, 2021, 49, ⟨10.1093/nar/gkab402⟩
Nucleic Acids Research, Oxford University Press, 2021, 49, ⟨10.1093/nar/gkab402⟩
Nucleic Acids Research, 2021, 49, ⟨10.1093/nar/gkab402⟩
Nucleic Acids Research, Oxford University Press, 2021, 49, ⟨10.1093/nar/gkab402⟩
With the dramatic increase of pangenomic analysis, Human geneticists have generated large amount of genomic data including millions of small variants (SNV/indel) but also thousands of structural variations (SV) mainly from next-generation sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8105caf4d61ce8eab00029b9c05be7ee
https://doi.org/10.1093/nar/gkab402
https://doi.org/10.1093/nar/gkab402