Low-cost and clinically applicable copy number profiling using repeat DNA

Autor: S Jammula, A Lynch, Yeng Ang, Charles Crichton, Andrew D Beggs, T Hupp, van Lanschot Mcv., S Puig, F Ciccarelli, L Lovat, E. Fidziukiewicz, J Bornschein, N Carroll, M Lewis, J Owsley, S Abujudeh, R D la Rue, M Tripathi, A J Metz, H Barr, A Miremadi, Jason Crawte, Shaun R. Preston, S Oakes, C Peters, Simon Tavaré, Juliane Perner, O Tucker, B Kumar, C Harden, V Goh, G Devonshire, S Hayes, P Safranek, Laszlo Igali, Andy G. Lynch, J Zylstra, Barbara Nutzinger, Oesophageal Cancer Clinical, A Noorani, I Bagwan, J Gossage, A Davies, A. Northrop, Irshad Soomro, Jim Davies, X Li, Shalini Malhotra, Nicola Grehan, G Sanders, P Kaye, Lawrence Bower, P Taniere, V Save, Edwards Paw., Christopher C.W. Hughes, Rehan Haidry, S Parsons, E Cheong, A Hindmarsh, N Shepherd, Ula Mahadeva, Edward Morrissey, J Saunders, F Chang, M Eldridge, Maria O'Donovan, R O’Neill, S Lishman, S S Zeki, Michael F. Scott, G Hanna, T Underwood, Weaver Jmj., Rebecca C. Fitzgerald, M Pusung, S Sothi, Maria Secrier, S Suortamo, R Berrisford, Skipworth Rje., Shona MacRae, F Noble, R Fitzgerald, J Lagergren, A Grabowska, O Old, V Sujendran, R Turkington, Gianmarco Contino

Large-scale cancer genome studies suggest that tumors are driven by somatic copy number alterations (SCNAs) or single-nucleotide variants (SNVs). Due to the low-cost, the clinical use of genomics assays is biased towards targeted gene panels, which i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1841052f772eaaa01655d5864053eda
https://doi.org/10.1101/394429

Response to: Immune-mediated toxicity leading to organ failure may achieve good outcomes from ICU admission.

Autor: Weaver JMJ; Department of Acute Medicine, The Christie, Wilmslow Road, Manchester, UK.; Department of Medical Oncology, The Christie, Wilmslow Road, Manchester, UK., Cooksley T; Department of Acute Medicine, The Christie, Wilmslow Road, Manchester, UK.; Department of Medical Oncology, The Christie, Wilmslow Road, Manchester, UK.

Publikováno v: QJM : monthly journal of the Association of Physicians [QJM] 2024 Feb 07; Vol. 117 (1), pp. 84.

Intensive care unit requirements in patients treated with immune checkpoint inhibitors.

Autor: Cooksley T; From the Department of Acute Medicine, Medical Oncology and Critical Care, The Christie, Wilmslow Road, Manchester, UK., Weaver JMJ; From the Department of Acute Medicine, Medical Oncology and Critical Care, The Christie, Wilmslow Road, Manchester, UK., Haji-Michael P; From the Department of Acute Medicine, Medical Oncology and Critical Care, The Christie, Wilmslow Road, Manchester, UK.

Publikováno v: QJM : monthly journal of the Association of Physicians [QJM] 2023 Apr 29; Vol. 116 (4), pp. 285-287.

Rearrangement processes and structural variations show evidence of selection in oesophageal adenocarcinomas.

Autor: Ng AWT; Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Contino G; Institute of Cancer and Genomic Sciences, College of Medical & Dental Sciences, University of Birmingham, Birmingham, UK.; University Hospitals Birmingham NHS Foundation Trust, Birmingham, B15 2GW, UK., Killcoyne S; Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute EMBL-EBI, Hinxton, UK., Devonshire G; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Hsu R; Department of Surgery, University of Cambridge, Cambridge, UK., Abbas S; Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, UK., Su J; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Redmond AM; Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, UK., Weaver JMJ; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Department of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Eldridge MD; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Tavaré S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Irving Institute for Cancer Dynamics, Columbia University, New York, USA.; Department of Statistics, Columbia University, New York, USA.; Department of Biological Sciences, Columbia University, New York, USA., Edwards PAW; Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Fitzgerald RC; Medical Research Council Cancer Unit, Hutchison/Medical Research Council Research Centre, University of Cambridge, Cambridge, UK. rcf29@cam.ac.uk.

Publikováno v: Communications biology [Commun Biol] 2022 Apr 08; Vol. 5 (1), pp. 335. Date of Electronic Publication: 2022 Apr 08.

CamGFR v2: A New Model for Estimating the Glomerular Filtration Rate from Standardized or Non-standardized Creatinine in Patients with Cancer.

Autor: Williams EH; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England, United Kingdom., Flint TR; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, United Kingdom., Connell CM; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England, United Kingdom.; University of Cambridge, Cambridge, England, United Kingdom., Giglio D; Department of Oncology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden., Lee H; University of Cambridge School of Clinical Medicine, Cambridge, England, United Kingdom., Ha T; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York., Gablenz E; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York., Bird NJ; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, United Kingdom., Weaver JMJ; The Christie NHS Foundation Trust, Manchester, England, United Kingdom.; University of Manchester, Manchester, England, United Kingdom., Potts H; University of Cambridge School of Clinical Medicine, Cambridge, England, United Kingdom., Whitley CT; University of Cambridge School of Clinical Medicine, Cambridge, England, United Kingdom., Bookman MA; Gynecologic Oncology Therapeutics, Kaiser Permanente, San Francisco, California., Lynch AG; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England, United Kingdom.; School of Medicine, University of St Andrews, St Andrews, Scotland, United Kingdom.; School of Mathematics and Statistics, University of St Andrews, St Andrews, Scotland, United Kingdom., Meyer HV; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York., Tavaré S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, England, United Kingdom.; Columbia University, New York, New York., Janowitz T; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. Janowitz@cshl.edu.; Northwell Health, New York, New York.

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Mar 01; Vol. 27 (5), pp. 1381-1390. Date of Electronic Publication: 2020 Dec 10.