Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Weang Kee Ho"'
Autor:
Peh Joo Ho, Weang Kee Ho, Alexis J. Khng, Yen Shing Yeoh, Benita Kiat-Tee Tan, Ern Yu Tan, Geok Hoon Lim, Su-Ming Tan, Veronique Kiak Mien Tan, Cheng-Har Yip, Nur-Aishah Mohd-Taib, Fuh Yong Wong, Elaine Hsuen Lim, Joanne Ngeow, Wen Yee Chay, Lester Chee Hao Leong, Wei Sean Yong, Chin Mui Seah, Siau Wei Tang, Celene Wei Qi Ng, Zhiyan Yan, Jung Ah Lee, Kartini Rahmat, Tania Islam, Tiara Hassan, Mei-Chee Tai, Chiea Chuen Khor, Jian-Min Yuan, Woon-Puay Koh, Xueling Sim, Alison M. Dunning, Manjeet K. Bolla, Antonis C. Antoniou, Soo-Hwang Teo, Jingmei Li, Mikael Hartman
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Family history, and genetic and non-genetic risk factors can stratify women according to their individual risk of developing breast cancer. The extent of overlap between these risk predictors is not clear. Methods In this case-onl
Externí odkaz:
https://doaj.org/article/a1cd5204e97c4a85a285a67209cba529
Publikováno v:
Journal of Nutritional Science, Vol 12 (2023)
The soya–breast cancer risk relationship remains controversial in Asia due to limited and inconsistent research findings and is exacerbated by difficulties in recruiting and retaining participants in intervention trials. Understanding public percep
Externí odkaz:
https://doaj.org/article/0d29d4c0fd7449958a254bc93fb15a35
Autor:
Xiang Shu, Jirong Long, Qiuyin Cai, Sun-Seog Kweon, Ji-Yeob Choi, Michiaki Kubo, Sue K. Park, Manjeet K. Bolla, Joe Dennis, Qin Wang, Yaohua Yang, Jiajun Shi, Xingyi Guo, Bingshan Li, Ran Tao, Kristan J. Aronson, Kelvin Y. K. Chan, Tsun L. Chan, Yu-Tang Gao, Mikael Hartman, Weang Kee Ho, Hidemi Ito, Motoki Iwasaki, Hiroji Iwata, Esther M. John, Yoshio Kasuga, Ui Soon Khoo, Mi-Kyung Kim, Sun-Young Kong, Allison W. Kurian, Ava Kwong, Eun-Sook Lee, Jingmei Li, Artitaya Lophatananon, Siew-Kee Low, Shivaani Mariapun, Koichi Matsuda, Keitaro Matsuo, Kenneth Muir, Dong-Young Noh, Boyoung Park, Min-Ho Park, Chen-Yang Shen, Min-Ho Shin, John J. Spinelli, Atsushi Takahashi, Chiuchen Tseng, Shoichiro Tsugane, Anna H. Wu, Yong-Bing Xiang, Taiki Yamaji, Ying Zheng, Roger L. Milne, Alison M. Dunning, Paul D. P. Pharoah, Montserrat García-Closas, Soo-Hwang Teo, Xiao-ou Shu, Daehee Kang, Douglas F. Easton, Jacques Simard, Wei Zheng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
In breast cancer, genome-wide associations studies (GWAS) have highlighted loci associated with disease risk. Here, the authors perform a meta-analysis of GWAS data from Asian populations, discovering 31 potential new risk loci, 10 of which are valid
Externí odkaz:
https://doaj.org/article/532b4d0876ab46de877da9effc1e588e
Autor:
John W Cole, Huichun Xu, Kathleen Ryan, Thomas Jaworek, Nicole Dueker, Patrick McArdle, Brady Gaynor, Yu-Ching Cheng, Jeffrey O'Connell, Steve Bevan, Rainer Malik, Naveed Uddin Ahmed, Philippe Amouyel, Sheraz Anjum, Joshua C Bis, David Crosslin, John Danesh, Stefan T Engelter, Myriam Fornage, Philippe Frossard, Christian Gieger, Anne-Katrin Giese, Caspar Grond-Ginsbach, Weang Kee Ho, Elizabeth Holliday, Jemma Hopewell, M Hussain, W Iqbal, S Jabeen, Jim Jannes, Ayeesha Kamal, Yoichiro Kamatani, Sandip Kanse, Manja Kloss, Mark Lathrop, Didier Leys, Arne Lindgren, W T Longstreth, Khalid Mahmood, Christa Meisinger, Tiina M Metso, Thomas Mosley, Martina Müller-Nurasyid, Bo Norrving, Eugenio Parati, Annette Peters, Alessandro Pezzini, I Quereshi, Asif Rasheed, A Rauf, T Salam, Jess Shen, Agnieszka Słowik, Tara Stanne, Konstantin Strauch, Turgut Tatlisumak, Vincent N Thijs, Steffen Tiedt, Matthew Traylor, Melanie Waldenberger, Matthew Walters, Wei Zhao, Giorgio Boncoraglio, Stéphanie Debette, Christina Jern, Christopher Levi, Hugh Markus, James Meschia, Arndt Rolfs, Peter Rothwell, Danish Saleheen, Sudha Seshadri, Pankaj Sharma, Cathie Sudlow, Bradford Worrall, METASTROKE Consortium of the ISGC, WTCCC-2 Consortium, O Colin Stine, Steven J Kittner, Braxton D Mitchell
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206554 (2018)
Background and purposePolymorphisms in coagulation genes have been associated with early-onset ischemic stroke. Here we pursue an a priori hypothesis that genetic variation in the endothelial-based receptors of the thrombomodulin-protein C system (TH
Externí odkaz:
https://doaj.org/article/d7e9695d35ae48c8af23ab47b2c3c8b2
Autor:
Leonardo Bottolo, Marc Chadeau-Hyam, David I Hastie, Tanja Zeller, Benoit Liquet, Paul Newcombe, Loic Yengo, Philipp S Wild, Arne Schillert, Andreas Ziegler, Sune F Nielsen, Adam S Butterworth, Weang Kee Ho, Raphaële Castagné, Thomas Munzel, David Tregouet, Mario Falchi, François Cambien, Børge G Nordestgaard, Fredéric Fumeron, Anne Tybjærg-Hansen, Philippe Froguel, John Danesh, Enrico Petretto, Stefan Blankenberg, Laurence Tiret, Sylvia Richardson
Publikováno v:
PLoS Genetics, Vol 9, Iss 8, p e1003657 (2013)
Genome-wide association studies (GWAS) yielded significant advances in defining the genetic architecture of complex traits and disease. Still, a major hurdle of GWAS is narrowing down multiple genetic associations to a few causal variants for functio
Externí odkaz:
https://doaj.org/article/04215bf109bd4b26bf33359fa7762e3c
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention; Oct2024, Vol. 33 Issue 10, p1273-1285, 13p
Autor:
Nadia Rajaram, Beverley Yap, Mikael Eriksson, Shivaani Mariapun, Lee Mei Tan, Hamizah Saat, Evelyn Ho, Nur Aishah Mohd Taib, Geok Lin Khor, Cheng Har Yip, Weang Kee Ho, Per Hall, Soo Hwang Teo
Publikováno v:
Cancer Research. 83:P2-06
Introduction: Soy intake is associated with lower breast cancer risk in observational studies of Asian women, but clinical trials of soy isoflavone (ISF) supplements report no effect on biomarkers of breast cancer risk among Caucasian women. To date,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9df647b0df7663dab254a04c002dadef
https://doi.org/10.1158/1538-7445.sabcs22-p2-06-02
https://doi.org/10.1158/1538-7445.sabcs22-p2-06-02
Predicting the Likelihood of Carrying a BRCA1 or BRCA2 Mutation in Asian Patients With Breast Cancer
Autor:
Boon Hong Ang, Weang Kee Ho, Eldarina Wijaya, Pui Yoke Kwan, Pei Sze Ng, Sook Yee Yoon, Siti Norhidayu Hasan, Joanna M.C. Lim, Tiara Hassan, Mei-Chee Tai, Jamie Allen, Andrew Lee, Nur Aishah Mohd Taib, Cheng Har Yip, Mikael Hartman, Swee Ho Lim, Ern Yu Tan, Benita K.T. Tan, Su-Ming Tan, Veronique K.M. Tan, Peh Joo Ho, Alexis J. Khng, Alison M. Dunning, Jingmei Li, Douglas F. Easton, Antonis C. Antoniou, Soo Hwang Teo
Publikováno v:
Journal of Clinical Oncology. 40:1542-1551
PURPOSE With the development of poly (ADP-ribose) polymerase inhibitors for treatment of patients with cancer with an altered BRCA1 or BRCA2 gene, there is an urgent need to ensure that there are appropriate strategies for identifying mutation carrie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1830af820964f59029821bd637f61735
https://doi.org/10.1200/jco.21.01647
https://doi.org/10.1200/jco.21.01647
Autor:
Weang-Kee Ho, Mei-Chee Tai, Joe Dennis, Xiang Shu, Jingmei Li, Peh Joo Ho, Iona Y. Millwood, Kuang Lin, Yon-Ho Jee, Su-Hyun Lee, Nasim Mavaddat, Manjeet K. Bolla, Qin Wang, Kyriaki Michailidou, Jirong Long, Eldarina Azfar Wijaya, Tiara Hassan, Kartini Rahmat, Veronique Kiak Mien Tan, Benita Kiat Tee Tan, Su Ming Tan, Ern Yu Tan, Swee Ho Lim, Yu-Tang Gao, Ying Zheng, Daehee Kang, Ji-Yeob Choi, Wonshik Han, Han-Byoel Lee, Michiki Kubo, Yukinori Okada, Shinichi Namba, Sue K. Park, Sung-Won Kim, Chen-Yang Shen, Pei-Ei Wu, Boyoung Park, Kenneth R. Muir, Artitaya Lophatananon, Anna H. Wu, Chiu-Chen Tseng, Keitaro Matsuo, Hidemi Ito, Ava Kwong, Tsun L. Chan, Esther M. John, Allison W. Kurian, Motoki Iwasaki, Taiki Yamaji, Sun-Seog Kweon, Kristan J. Aronson, Rachel A. Murphy, Woon-Puay Koh, Chiea-Chuen Khor, Jian-Min Yuan, Rajkumar Dorajoo, Robin G. Walters, Zhengming Chen, Liming Li, Jun Lv, Keum-Ji Jung, Peter Kraft, Paul D.B. Pharoah, Alison M. Dunning, Jacques Simard, Xiao-Ou Shu, Cheng-Har Yip, Nur Aishah Mohd Taib, Antonis C. Antoniou, Wei Zheng, Mikael Hartman, Douglas F. Easton, Soo-Hwang Teo
Publikováno v:
Genetics in Medicine. 24:586-600
Purpose Non-European populations are under-represented in genetics studies, hindering clinical implementation of breast cancer polygenic risk scores (PRSs). We aimed to develop PRSs using the largest available studies of Asian ancestry and to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac076d8c94f01891867da9bb7b3c493d
https://doi.org/10.1016/j.gim.2021.11.008
https://doi.org/10.1016/j.gim.2021.11.008
Autor:
Soo Hwang Teo, Cheng Har Yip, Sara Lindström, Jingmei Li, Peter Choon Eng Kang, Weang Kee Ho, Shivaani Mariapun
Supplementary Table 1. Characteristics of subjects by ethnicity Supplementary Table 2. SNPs selected for genotyping Supplementary Table 3. Analysis of SNPs associated with percent mammographic density, mammographic dense area, mammographic nondense a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::286d76ed60a29b4bcd8a4212ef08441e
https://doi.org/10.1158/1055-9965.22438692
https://doi.org/10.1158/1055-9965.22438692
