Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Weam Shahin"'
Autor:
Nan He, Xiaoming Liu, Amber R. Vegter, T. Idil A. Evans, Jaimie S. Gray, Junfeng Guo, Shashanna R. Moll, Lydia J. Guo, Meihui Luo, Ningxia Ma, Xingshen Sun, Bo Liang, Ziying Yan, Zehua Feng, Lisi Qi, Arnav S. Joshi, Weam Shahin, Yaling Yi, Katherine N. Gibson-Corley, Eric A. Hoffman, Kai Wang, Christian Mueller, John F. Engelhardt, Bradley H. Rosen
Publikováno v:
JCI Insight, Vol 7, Iss 5 (2022)
Alpha-1 antitrypsin deficiency (AATD) is the most common genetic cause and risk factor for chronic obstructive pulmonary disease, but the field lacks a large-animal model that allows for longitudinal assessment of pulmonary function. We hypothesized
Externí odkaz:
https://doaj.org/article/628dc438f0564d82ab0c2f15a8972688
Autor:
Vitaly Ievlev, Chandler C Jensen-Cody, Thomas J Lynch, Albert C Pai, Soo Park, Weam Shahin, Kai Wang, Kalpaj R Parekh, John F Engelhardt
Publikováno v:
Stem Cells
Cartilaginous airways of larger mammals and the mouse trachea contain at least 3 well-established stem cell compartments, including basal cells of the surface airway epithelium (SAE) and ductal and myoepithelial cells of the submucosal glands (SMG).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3822a9b311ab5608b872e8d62c17f977
https://europepmc.org/articles/PMC9406614/
https://europepmc.org/articles/PMC9406614/
Autor:
Adrianne K. Crooke, Chandler W. Jensen-Cody, Thomas J. Lynch, Vitaly Ievlev, John F. Engelhardt, Pavana G. Rotti, Weam Shahin, Soo-Yeun Park
Publikováno v:
Stem Cells
The mammalian airways are lined by a continuous epithelial layer that is maintained by diverse populations of resident multipotent stem cells. These stem cells are responsible for replenishing the epithelium both at homeostasis and following injury,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa71ec54c39747ac4295a38db94daf4a
https://europepmc.org/articles/PMC8785221/
https://europepmc.org/articles/PMC8785221/
Autor:
Nan He, Xiaoming Liu, Amber R. Vegter, T. Idil A. Evans, Jaimie S. Gray, Junfeng Guo, Shashanna R. Moll, Lydia J. Guo, Meihui Luo, Ningxia Ma, Xingshen Sun, Bo Liang, Ziying Yan, Zehua Feng, Lisi Qi, Arnav S. Joshi, Weam Shahin, Yaling Yi, Katherine N. Gibson-Corley, Eric A. Hoffman, Kai Wang, Christian Mueller, John F. Engelhardt, Bradley H. Rosen
Publikováno v:
JCI insight. 7(5)
Alpha-1 antitrypsin deficiency (AATD) is the most common genetic cause and risk factor for chronic obstructive pulmonary disease, but the field lacks a large-animal model that allows for longitudinal assessment of pulmonary function. We hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579656c0af233ba09095d9ae72025263
https://pubmed.ncbi.nlm.nih.gov/35104244
https://pubmed.ncbi.nlm.nih.gov/35104244
Autor:
Weam Shahin, Thomas J. Lynch, Soon H. Choi, Bo Liang, John F. Engelhardt, Scott R. Tyler, Feng Yuan, Xingshen Sun, Anthony M. Swatek, Xiaoming Liu, Nan He, Zehua Feng, Ziying Yan, Pavana G. Rotti, Miao Yu
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
The domestic ferret (Mustela putorius furo) has proven to be a useful species for modeling human genetic and infectious diseases of the lung and brain. However, biomedical research in ferrets has been hindered by the lack of rapid and cost-effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47f03e7a294d0e1f914cd54a1385b26
Autor:
John F. Engelhardt, Weam Shahin
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994236
Reactive oxygen species (ROS) convey signals essential for proliferation, maintenance, and senescence of a growing list of cell types. Compartmentalization of these signals is integral to cell viability as well as the signaling pathways ROS direct. R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84945428aacefc9684aaf8fd4dc4c329
https://doi.org/10.1007/978-1-4939-9424-3_27
https://doi.org/10.1007/978-1-4939-9424-3_27
Autor:
Kalpaj R. Parekh, Adrianne K. Crooke, Thomas J. Lynch, Andrea Adamcakova-Dodd, Pavana G. Rotti, Scott R. Tyler, Carolyn L. Silverman, Weam Shahin, John F. Engelhardt, B. Paul Herring, Weiliang Xie, Charles Yeaman, Daniel T. Montoro, Hongmei Mou, Rui Zhao, Peter S. Thorne, Jayaraj Rajagopal, Soon H. Choi, Chandler W. Jensen-Cody, Preston J. Anderson, Yulong Zhang, T. Idil Apak Evans
Summary The mouse trachea is thought to contain two distinct stem cell compartments that contribute to airway repair—basal cells in the surface airway epithelium (SAE) and an unknown submucosal gland (SMG) cell type. Whether a lineage relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f98efa5c3b8838413a1b269f9e3d47
https://europepmc.org/articles/PMC5935589/
https://europepmc.org/articles/PMC5935589/