Effect of pH on weakly acidic and basic model drugs and determination of their ex vivo transdermal permeation routes

Autor: Lakshmi P.K., Pranitha Akula

Publikováno v: Brazilian Journal of Pharmaceutical Sciences; Vol. 54 No. 2 (2018); e00070
Brazilian Journal of Pharmaceutical Sciences; Vol. 54 Núm. 2 (2018); e00070
Brazilian Journal of Pharmaceutical Sciences; v. 54 n. 2 (2018); e00070
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP
Brazilian Journal of Pharmaceutical Sciences, Vol 54, Iss 2 (2018)

The aim of the present study was to investigate the effect of donor pH on the transdermal permeability of the model drugs across rat skin and also to determine the major route of transport of the drugs. Weakly acidic drugs (partition coefficient) ibu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f0e8912fc23ca60179f2c3b393a151
https://www.revistas.usp.br/bjps/article/view/153773

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