Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Wayne Tam"'
Autor:
C. Cameron Yin, Wayne Tam, Serena M. Walker, Amandeep Kaur, Madhu M. Ouseph, Wei Xie, Olga K.Weinberg, Peng Li, Zhuang Zuo, Mark J. Routbort, Simon Chen, L. Jeffrey Medeiros, Tracy I George, Attilio Orazi, Daniel A. Arber, Adam Bagg, Robert P. Hasserjian, Sa A. Wang
Publikováno v:
Haematologica, Vol 109, Iss 6 (2023)
STAT5B has been reported as a recurrent mutation in myeloid neoplasms with eosinophilia, but its overall frequency and importance across a spectrum of myeloid neoplasms are largely unknown. We conducted a multicenter study on a series of 82 myeloid n
Externí odkaz:
https://doaj.org/article/d278b8f93dc24bc5a9ea8b492101f78d
Autor:
Luca Vincenzo Cappelli, Danilo Fiore, Liu Zhaoqi, Nikita Kotlov, Jude Phillip, Paul Zumbo, Liron Yoffe, Claudia Pignataro, Paola Ghione, Han Xueshuai, Valentina Fragliasso, Gerolama Condorelli, Robin Foà, Joshua Brody, Doron Betel, John Chan, Wayne Tam, David Weinstock, Leandro Cerchietti, Raul Rabadan, Steven Horwitz, Giorgio Inghirami
Publikováno v:
HemaSphere, Vol 7, p e58193ee (2023)
Externí odkaz:
https://doaj.org/article/7d2660d378924dc28b6db15624027e3e
Autor:
Danilo Fiore, Luca Vincenzo Cappelli, Liu Zhaoqi, Nikita Kotlov, Maria Sorokina, Jude Phillip, Paul Zumbo, Liron Yoffe, Han Xueshuai, Claudia Pignataro, Paola Ghione, Valentina Fragliasso, Gerolama Condorelli, Robin Foà, Joshua Brody, Doron Betel, Wing C Chan, Wayne Tam, Anastasie Nikitina, Aleksander Bagaev, Nathan Fowler, David Weinstock, Leandro Cerchietti, Raul Rabadan, Steve Horwitz, Giorgio Inghirami
Publikováno v:
HemaSphere, Vol 7, p e8686389 (2023)
Externí odkaz:
https://doaj.org/article/ac0ba3f3a2254b25bcc9944460c428ab
Autor:
Maher Albitar, Hong Zhang, Andre Goy, Zijun Y. Xu-Monette, Govind Bhagat, Carlo Visco, Alexandar Tzankov, Xiaosheng Fang, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, Fredrick B. Hagemeister, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Benjamin M. Parsons, J. Han van Krieken, Miguel A. Piris, Jane N. Winter, Yong Li, Bing Xu, Ken H. Young
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 2, Pp 1-9 (2022)
Abstract Multiple studies have demonstrated that diffuse large B-cell lymphoma (DLBCL) can be divided into subgroups based on their biology; however, these biological subgroups overlap clinically. Using machine learning, we developed an approach to s
Externí odkaz:
https://doaj.org/article/93888a803eda4609ab485bda57596d9c
Publikováno v:
Human Pathology Reports, Vol 29, Iss , Pp 300672- (2022)
Merkel cell carcinoma (MCC), a rare and aggressive skin tumor, has a tendency to occur in association with hematologic malignancies, in particular chronic lymphocytic leukemia (CLL). The permissive immunologic environment and Merkel cell polyoma viru
Externí odkaz:
https://doaj.org/article/1a381ca137a741069279ca51f1a93b56
Autor:
Mayumi Sugita, David C. Wilkes, Rohan Bareja, Kenneth W. Eng, Sarah Nataraj, Reyna A. Jimenez-Flores, LunBiao Yan, Jeanne Pauline De Leon, Jaclyn A. Croyle, Justin Kaner, Swathi Merugu, Sahil Sharma, Theresa Y. MacDonald, Zohal Noorzad, Palak Panchal, Danielle Pancirer, Shuhua Cheng, Jenny Z. Xiang, Luke Olson, Koen Van Besien, David S. Rickman, Susan Mathew, Wayne Tam, Mark A. Rubin, Himisha Beltran, Andrea Sboner, Duane C. Hassane, Gabriela Chiosis, Olivier Elemento, Gail J. Roboz, Juan Miguel Mosquera, Monica L. Guzman
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-10 (2021)
Abstract The epichaperome is a new cancer target composed of hyperconnected networks of chaperome members that facilitate cell survival. Cancers with an altered chaperone configuration may be susceptible to epichaperome inhibitors. We developed a flo
Externí odkaz:
https://doaj.org/article/9b26f08bf6d444edb5f3140c7fcddf4c
Autor:
Manman Deng, Mingzhi Zhang, Zijun Y. Xu-Monette, Lan V. Pham, Alexandar Tzankov, Carlo Visco, Xiaosheng Fang, Govind Bhagat, Feng Zhu, Karen Dybkaer, April Chiu, Wayne Tam, Youli Zu, Eric D. Hsi, William W. L. Choi, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Benjamin M. Parsons, J. Han van Krieken, Miguel A. Piris, Jane N. Winter, Fredrick Hagemeister, Lapo Alinari, Yong Li, Michael Andreeff, Bing Xu, Ken H. Young
Publikováno v:
Journal of Hematology & Oncology, Vol 13, Iss 1, Pp 1-5 (2020)
Abstract The XPO1 inhibitor selinexor was recently approved in relapsed/refractory DLBCL patients but only demonstrated modest anti-DLBCL efficacy, prompting us to investigate the prognostic effect of XPO1 in DLBCL patients and the rational combinati
Externí odkaz:
https://doaj.org/article/c7f6b942461b4f9b84f6332a99a2ce26
Autor:
Zijun Y. Xu-Monette, Jianyong Li, Yi Xia, Beryl Crossley, Robert D. Bremel, Yi Miao, Min Xiao, Thomas Snyder, Ganiraju C. Manyam, Xiaohong Tan, Hongwei Zhang, Carlo Visco, Alexandar Tzankov, Karen Dybkaer, Govind Bhagat, Wayne Tam, Hua You, Eric D. Hsi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Miguel A. Piris, Jane N. Winter, Jeffrey T. Medeiros, Bing Xu, Yong Li, Ilan Kirsch, Ken H. Young
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Background Diffuse large B-cell lymphoma (DLBCL) harbors somatic hypermutation (SHM) in the immunoglobulin heavy chain and light chain variable region genes, IGHV and IGK/LV. Recent studies have revealed that IGV SHM creates neoantigens that
Externí odkaz:
https://doaj.org/article/4d22ed39e9c44774bc0de47c25ddda03
Publikováno v:
eLife, Vol 10 (2021)
Background: Although advance has been made in understanding the pathogenesis of mature T-cell neoplasms, the initiation and progression of angioimmunoblastic T-cell lymphoma (AITL) and peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS), r
Externí odkaz:
https://doaj.org/article/a27d55bdfc5a40f69b987bae0c445bcb
Autor:
Amanda Lopez, Sanjay Patel, Julia T. Geyer, Joelle Racchumi, Amy Chadburn, Paul Simonson, Madhu M. Ouseph, Giorgio Inghirami, Nuria Mencia-Trinchant, Monica L. Guzman, Alexandra Gomez-Arteaga, Sangmin Lee, Pinkal Desai, Ellen K. Ritchie, Gail J. Roboz, Wayne Tam, Michael J. Kluk
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundNPM1 mutation status can influence prognosis and management in AML. Accordingly, clinical testing (i.e., RT-PCR, NGS and IHC) for mutant NPM1 is increasing in order to detect residual disease in AML, alongside flow cytometry (FC). However,
Externí odkaz:
https://doaj.org/article/f8a72db61b544a4bb1c2cd20d3ec0754