Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Wayne T. Brashear"'
Autor:
Kenneth D.R. Setchell, Wayne T Brashear, James E. Heubi, Nadine M Brown, Brian Wolfe, Abby S. Kirschner, Linda Zimmer-Nechemias
Publikováno v:
The American Journal of Clinical Nutrition. 76:447-453
Background The isoflavones daidzein and genistein occur naturally in most soyfoods, conjugated almost exclusively to sugars. Controversy exists regarding the extent of bioavailability of isoflavone glycosides, and the mechanism of intestinal absorpti
Autor:
Pankaj B. Desai, Kenneth D.R. Setchell, Abby S. Kirschner, Nadine M Brown, Wayne T Brashear, Linda Zimmer-Nechemias, Aedin Cassidy, James E. Heubi, Brian Wolfe
Publikováno v:
The Journal of Nutrition. 131:1362S-1375S
The pharmacokinetic behavior of naturally occurring isoflavones has been determined for the first time in healthy adults. We compared plasma kinetics of pure daidzein, genistein and their beta-glycosides administered as a single-bolus dose to 19 heal
Autor:
David A. Putt, Lawrence H. Lash, Jean C. Parker, Jeffrey W. Fisher, Wayne T. Brashear, Richat Abbas
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 56:1-21
Healthy male and female human volunteers were exposed to 50 ppm or 100 ppm trichloroethylene (Tri) by inhalation for 4 h. Blood and urine samples were taken at various times before, during, and after the exposure period for analysis of glutathione (G
Publikováno v:
Journal of Analytical Toxicology. 21:330-334
Trichloroethylene (TCE) has been identified as a widespread groundwater contaminant. Trichloroacetic acid (TCA) and dichloroacetic acid (DCA) are toxicologically relevant metabolites of TCE that produce tumors in B6C3F1 mice. A sensitive method for m
Publikováno v:
Journal of Analytical Toxicology. 16:28-32
3.1 Oil, referred to as polychlorotrifluoroethylene (pCTFE), is a polymeric mixture consisting primarily of trimers and tetramers of chlorotrifluoroethylene (CTFE) end-capped with chlorine. Inhalation studies have associated dose-related body weight
Autor:
John S. Olson, Paul R. Gardner, Angela N. Hvitved, Wayne T Brashear, Kenneth D.R. Setchell, Tomohiko Suzuki, Anne M. Gardner
Publikováno v:
Journal of inorganic biochemistry. 100(4)
Distantly related members of the hemoglobin (Hb) superfamily including red blood cell Hb, muscle myoglobin (Mb) and the microbial flavohemoglobin (flavoHb) dioxygenate nitric oxide (.NO). The reaction serves important roles in .NO metabolism and deto
Autor:
Wayne T Brashear, Panjak Desai, Aedin Cassidy, Marian S. Faughnan, Nadine M Brown, Nigel P. Botting, Kenneth D.R. Setchell, Brian Wolfe, Tony Avades, Mark F. Oldfield, Linda Zimmer-Nechemias
Publikováno v:
The American journal of clinical nutrition. 77(2)
Background: Despite significant interest in the risks and benefits of phytoestrogens to human health, few data exist on their pharmacokinetics in humans. Objective: We investigated the pharmacokinetics of the 13 C isotopic forms of daidzein and genis
Publikováno v:
Anesthesia & Analgesia. 72:369
This study was undertaken to determine the effect, if any, of ranitidine on bupivacaine disposition in 28 women undergoing cesarean section. Before epidural anesthesia, ranitidine (50 mg IM) or sodium citrate (30 mL orally) was administered to groups
Autor:
Wayne T. Brashear, Betty R. Kuhnert, C. D. Syracuse, Philip C. Carr, Leon I. Mann, Noam Lazebnik
Publikováno v:
American Journal of Obstetrics and Gynecology. 160:1184-1189
It has been suggested, but not well verified, that drug absorption from traditional intramuscular injection sites is altered during labor. This study tested the hypothesis that absorption of meperidine from the gluteus muscle would be impeded when co