Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Wayne R. Kindsvogel"'
Autor:
Syed-Rehan A. Hussain, Carolyn Cheney, David Jarjoura, Julie M. Roda, Wayne R. Kindsvogel, William E. Carson, Susheela Tridandapani, Michael A. Caligiuri, Xiaoli Zhang, Trupti Joshi, Amy Lehman, Susan E Schmidt, Natarajan Muthusamy, John C. Byrd, Asha Ramanunni, Aruna Gowda
Publikováno v:
Blood. 111:4723-4730
Interleukin-21 (IL-21) is a recently identified γ-chain receptor cytokine family member that promotes B-cell apoptosis as well as activation of innate immune system. Based on this, we hypothesized that IL-21 might enhance the apoptosis induced by fl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd4678e70446bf55e04b5996ee11531
https://doi.org/10.1182/blood-2007-07-099531
https://doi.org/10.1182/blood-2007-07-099531
Autor:
Wayne R. Kindsvogel, Jane A. Gross, Harald S. Haugen, Alisa Littau, Christopher H. Clegg, Angelika Grossman, Margaret D. Moore, Sherri Mudri, Julia Parrish-Novak, Rachel Enselman, Janet V. Johnston, Hal Blumberg, Don Foster, Wenfeng Xu, Karen L. Madden, Stacey R. Dillon, Catherine Lofton-Day, Kevin P. Foley, Kim Harrison
Publikováno v:
Nature. 404:995-999
B cells are important in the development of autoimmune disorders by mechanisms involving dysregulated polyclonal B-cell activation, production of pathogenic antibodies, and co-stimulation of autoreactive T cells. zTNF4 (BLyS, BAFF, TALL-1, THANK) is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c8ea22566995ab7d4b3ac37f18a4d0
https://doi.org/10.1038/35010115
https://doi.org/10.1038/35010115
Autor:
Lars Hansen, Erica Nishimura, Ted Whitmore, Pierre Bouchelouche, Wayne R. Kindsvogel, Laura J. Jelinek, Jesper Gromada
Publikováno v:
Europe PubMed Central
From video imaging of fura 2-loaded baby hamster kidney (BHK) cells stably expressing the cloned human glucagon receptor, we found the Ca2+response to glucagon to be specific, dose dependent, synchronous, sensitive to pertussis toxin, and independent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b6790e44953ad4a84b8bdc766f2c1a
https://doi.org/10.1152/ajpcell.1998.274.6.c1552
https://doi.org/10.1152/ajpcell.1998.274.6.c1552
Autor:
Catherine Lofton-Day, William Hagopian, Wayne R. Kindsvogel, Laura J. Jelinek, Shannon L. Sexson, James Lagasse, John F. Breininger, Paul O. Sheppard
Publikováno v:
Molecular Medicine. 3:163-173
We sought to identify novel islet-cell autoantigens to better understand the pathogenesis, prediction, and immunotherapy of type 1 diabetes. Macaque and human islet cDNA libraries expressed in mammalian cells were screened with human diabetes sera. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14bfabad3d2f1025f98abac8a6020fcf
https://doi.org/10.1007/bf03401670
https://doi.org/10.1007/bf03401670
Autor:
Wayne R. Kindsvogel, Jörg Hager, Lars Hansen, Laura J. Jelinek, Erica Nishimura, Philippe Froguel, Niels Abrahamsen
Publikováno v:
Diabetes. 45:725-730
The pancreatic islet hormone, glucagon, stimulates hepatic glucose production and has also been shown to potentiate glucose-induced insulin secretion. Because glucagon is a key regulator of glucose homeostasis, its receptor, which mediates the action
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5990d78d38f0775f5223f257442b38
https://doi.org/10.2337/diab.45.6.725
https://doi.org/10.2337/diab.45.6.725
Autor:
Lisa Prichard, Gary A. Wayman, Zhiliang Wu, Daniel R. Storm, Wayne R. Kindsvogel, Soren Impey
Publikováno v:
Journal of Biological Chemistry. 269:25400-25405
The type I adenylyl cyclase is directly stimulated by Ca2+ and calmodulin in vivo (Choi, E. J., Wong, S. T., Hinds, T. R. and Storm, D. R. (1992) J. Biol. Chem. 267, 12440-12442; Wu, Z., Wong, S. T., and Storm, D. R. (1993) J. Biol. Chem. 268, 23766-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2026254dd77024d86cdb598dd2a00b1b
https://doi.org/10.1016/s0021-9258(18)47263-8
https://doi.org/10.1016/s0021-9258(18)47263-8
Autor:
Michael A. Kolber, Subramaniam Krishnan, Lesley J. White, Natasa Strbo, Savita Pahwa, Wayne R. Kindsvogel
Publikováno v:
Retrovirology, Vol 2, Iss Suppl 1, p P154 (2005)
Background HIV infection is associated with skewed maturation of CD8 T cells, accumulation of cells in pre-effector stages and impaired effector function. Two g-chain signaling cytokines, IL-21 and IL-15, are known to enhance IFN-g in antigen-specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6d7510ff1d75331dd97fdf74ce2590
https://doaj.org/article/e9b6f38f81a94fc4909e182fa81fdcab
https://doaj.org/article/e9b6f38f81a94fc4909e182fa81fdcab
Autor:
Jane A. Gross, Diane F. Jelinek, Anne J. Novak, Bonnie K. Arendt, Kathy Henderson, Wayne R. Kindsvogel, Jaime R. Darce, Brandon Harder, Philip R. Greipp
Publikováno v:
Blood. 103(2)
Multiple myeloma (MM) is a progressive disease that is thought to result from multiple genetic insults to the precursor plasma cell that ultimately affords the tumor cell with proliferative potential despite its differentiated phenotype and resistanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e8279ff639cbb834c81283998eadaf7
https://pubmed.ncbi.nlm.nih.gov/14512299
https://pubmed.ncbi.nlm.nih.gov/14512299
Autor:
Gary L. McKnight, William Krivan, Katherine E. Henderson, Ursula Garrigues, Scott R. Presnell, Wenfeng Xu, Dennis L. Dong, Brian A. Fox, Paul O. Sheppard, Stacy Schlutsmeyer, Wayne R. Kindsvogel, Rolf E. Kuestner, Carl W. Birks, Don Foster, Jenny Roraback, Chris Clegg, Emily Cooper, David W. Taft, Kevin M. Klucher, Tackett Monica L, Francis J. Grant, Teresa Gilbert, Craig D. Ostrander, Theodore E. Whitmore, Betty A. Haldeman, Jinu Shin
Publikováno v:
Nature immunology. 4(1)
Cytokines play a critical role in modulating the innate and adaptive immune systems. Here, we have identified from the human genomic sequence a family of three cytokines, designated interleukin 28A (IL-28A), IL-28B and IL-29, that are distantly relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8faada4bf975e2123323da63a61d1c5
https://pubmed.ncbi.nlm.nih.gov/12496969
https://pubmed.ncbi.nlm.nih.gov/12496969
Autor:
Wayne R. Kindsvogel, Stacey R. Dillon, Mark F. Maurer, Zhi Chen, Karen L. Madden, Yasmin A. Chandrasekher, Wenfeng Xu, Angie Hammond, Stavros Topouzis, Harold Storey, Theodore E. Whitmore, Christopher H. Clegg, Francis J. Grant, Donald C. Foster, Julia Parrish-Novak, Ty Brender, Zeren Gao, Steve Jaspers, Laura J. Jelinek, Scott R. Presnell, Teresa Gilbert, Stacy Schlutsmeyer, Lena Yao
IL-22 is an IL-10 homologue that binds to and signals through the class II cytokine receptor heterodimer IL-22RA1/CRF2–4. IL-22 is produced by T cells and induces the production of acute-phase reactantsin vitroandin vivo, suggesting its involvement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1e3c7119a1eca9c0d1f3aca9bda59f
https://europepmc.org/articles/PMC55483/
https://europepmc.org/articles/PMC55483/
