Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Wayne R Danter"'
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191766 (2018)
Emerging drug-resistance and drug-associated toxicities are two major factors limiting successful cancer therapy. Combinations of chemotherapeutic drugs have been used in the clinic to improve patient outcome. However, cancer cells can acquire resist
Externí odkaz:
https://doaj.org/article/adcfa712d5784690b5dfd7a3353f03ab
Autor:
Sally Esmail, Wayne R. Danter
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1701-1712 (2021)
The global pandemic caused by the SARS-CoV-2 virus continues to spread. Infection with SARS- CoV-2 causes COVID-19, a disease of variable severity. Mutation has already altered the SARS-CoV-2 genome from its original reported sequence and continued m
Externí odkaz:
https://doaj.org/article/7bad5ea5da0a4af18eb7317790ee8bcb
Autor:
Sally Esmail, Wayne R. Danter
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Alzheimer’s disease (AD) is the most common type of neurodegenerative diseases. There are over 44 million people living with the disease worldwide. While there are currently no effective treatments for AD, induced pluripotent stem cell-derived brai
Externí odkaz:
https://doaj.org/article/a86a5b9fa7df4ad194ab21ea6de20857
Autor:
Will Spagnoli, Wayne R Danter
The global pandemic caused by SARS-CoV-2 has highlighted the urgent need for effective antiviral drugs. The papain-like protease (PLpro) is a key viral enzyme involved in the replication and immune evasion of SARS-CoV-2, making it a promising target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69337e12c9560d5b31253894ca303ca4
https://doi.org/10.1101/2023.04.05.535700
https://doi.org/10.1101/2023.04.05.535700
Autor:
Sally Esmail, Wayne R. Danter
Publikováno v:
Biomedicines, Vol 9, Iss 4, p 440 (2021)
Metachromatic leukodystrophy (MLD) is a rare neurodegenerative disease that results from a deficiency of the lysosomal enzyme arylsulfatase A (ARSA). Worldwide, there are between one in 40,000 and one in 160,000 people living with the disease. While
Externí odkaz:
https://doaj.org/article/c9e63f4317614f9a89e6dc8be706da75
Autor:
Sally Ezra, Wayne R. Danter
The evolving global SARS-CoV-2 pandemic emphasizes how unprepared we are for the emergence of the next lethal viral pathogen. A list of potential candidates was created by the World Health Organization which named Nipah virus infection as the highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3446fef29e6e9769fa563c8af6e085d7
https://doi.org/10.20944/preprints202210.0217.v1
https://doi.org/10.20944/preprints202210.0217.v1
Autor:
Wayne R. Danter, Sally Esmail
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 1701-1712 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
The global pandemic caused by the SARS-CoV-2 virus continues to spread. Infection with SARS- CoV-2 causes COVID-19, a disease of variable severity. Mutation has already altered the SARS-CoV-2 genome from its original reported
The global pandemic caused by the SARS-CoV-2 virus continues to spread. Infection with SARS- CoV-2 causes COVID-19, a disease of variable severity. Mutation has already altered the SARS-CoV-2 genome from its original reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64823279f9a1e4c2e44eee14f2fc0da8
https://doi.org/10.1016/j.csbj.2021.03.020
https://doi.org/10.1016/j.csbj.2021.03.020
Autor:
Sally Esmail, Wayne R. Danter
Publikováno v:
STEM CELLS Translational Medicine
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 2, Pp 239-250 (2021)
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 2, Pp 239-250 (2021)
Infection with the SARS‐CoV‐2 virus has rapidly become a global pandemic for which we were not prepared. Several clinical trials using previously approved drugs and drug combinations are urgently underway to improve our current situation. Unfortu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3480b140e4b5caa7fb0e05e3641c67
https://doi.org/10.1002/sctm.20-0181
https://doi.org/10.1002/sctm.20-0181
Autor:
Sally Esmail, Wayne R. Danter
Publikováno v:
The FEBS journalReferences. 289(4)
Advanced high-grade serous ovarian cancer continues to be a therapeutic challenge for those affected using the current therapeutic interventions. There is an increasing interest in personalized cancer immunotherapy using activated natural killer (NK)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312fa70f694b854af07e175f16e12f0b
https://pubmed.ncbi.nlm.nih.gov/34582617
https://pubmed.ncbi.nlm.nih.gov/34582617