Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Wayne M Patrick"'
Autor:
Kay A Ramsay, Attika Rehman, Samuel T Wardell, Lois W Martin, Scott C Bell, Wayne M Patrick, Craig Winstanley, Iain L Lamont
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285856 (2023)
Pseudomonas aeruginosa causes a wide range of severe infections. Ceftazidime, a cephalosporin, is a key antibiotic for treating infections but a significant proportion of isolates are ceftazidime-resistant. The aim of this research was to identify mu
Externí odkaz:
https://doaj.org/article/54bc854609b84c83a03edbd6886ce667
Autor:
Kelsi R Hall, Katherine J Robins, Elsie M Williams, Michelle H Rich, Mark J Calcott, Janine N Copp, Rory F Little, Ralf Schwörer, Gary B Evans, Wayne M Patrick, David F Ackerley
Publikováno v:
eLife, Vol 9 (2020)
Selection for a promiscuous enzyme activity provides substantial opportunity for competition between endogenous and newly-encountered substrates to influence the evolutionary trajectory, an aspect that is often overlooked in laboratory directed evolu
Externí odkaz:
https://doaj.org/article/7322f1ca185a4740b5cf914fee329367
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0219879 (2019)
The crisis of antimicrobial resistance is driving research into the phenomenon of collateral sensitivity. Sometimes, when a bacterium evolves resistance to one antimicrobial, it becomes sensitive to others. In this study, we have investigated the uti
Externí odkaz:
https://doaj.org/article/866657b7174a43eb81287a69ff17c2d0
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83383 (2013)
Bacteria in the class Alphaproteobacteria have a wide variety of lifestyles and physiologies. They include pathogens of humans and livestock, agriculturally valuable strains, and several highly abundant marine groups. The ancestor of mitochondria als
Externí odkaz:
https://doaj.org/article/f49110c088a54bc099671559b60f8f73
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Oomycetes in the genus Phytophthora are among the most damaging plant pathogens worldwide. Two important species are Phytophthora cinnamomi, which causes root rot in thousands of native and agricultural plants, and Phytophthora agathidicida, which ca
Externí odkaz:
https://doaj.org/article/b542b813b80f414d9fc2068fce899040
Autor:
Elad Noor, Avi I. Flamholz, Vijay Jayaraman, Brian L. Ross, Yair Cohen, Wayne M. Patrick, Ita Gruic‐Sovulj, Dan S. Tawfik
Enzymes are well known for their catalytic abilities, some even reaching "catalytic perfection" in the sense that the reaction they catalyze has reached the physical bound of the diffusion rate. However, our growing understanding of enzyme superfamil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::144152ffc84fed9bff9f8ec00129e5a2
https://resolver.caltech.edu/CaltechAUTHORS:20220714-369203000
https://resolver.caltech.edu/CaltechAUTHORS:20220714-369203000
Autor:
Ichiro Matsumura, Wayne M. Patrick
Publikováno v:
Biochemistry.
Natural evolution has been creating new complex systems for billions of years. The process is spontaneous and requires neither intelligence nor moral purpose but is nevertheless difficult to understand. The late Dan Tawfik spent years studying enzyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936a7f6321663dbf8722e3f14690aafe
https://pubmed.ncbi.nlm.nih.gov/35820168
https://pubmed.ncbi.nlm.nih.gov/35820168
Publikováno v:
Protein Science : A Publication of the Protein Society
The ongoing biotechnological revolution is rooted in our knowledge of enzymes. However, metagenomics is showing how little we know about Earth's enzyme repertoire. Deep sequencing has revolutionized our view of the tree of life. The genomes of newly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7bb589d188c0361b9b5dc6fe38c166
https://doi.org/10.1002/pro.4041
https://doi.org/10.1002/pro.4041
Publikováno v:
Microbiology Resource Announcements. 11
In the process of studying the relationship between marine macroalgae and their bacterial symbionts, we isolated a new species of Rhizobium , which we designated Rhizobium sp. nov. C1 (for “ Codium 1”). Here, we report the complete genome sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28be0d5d2b8c6f6adb86995aadbf50c9
https://doi.org/10.1128/mra.00030-22
https://doi.org/10.1128/mra.00030-22
Autor:
Hannah M. Read, Grant Mills, Sarah Johnson, Peter Tsai, James Dalton, Lars Barquist, Cristin G. Print, Wayne M. Patrick, Siouxsie Wiles
Publikováno v:
PeerJ, Vol 4, p e2130 (2016)
Bioluminescent reporter genes, such as those from fireflies and bacteria, let researchers use light production as a non-invasive and non-destructive surrogate measure of microbial numbers in a wide variety of environments. As bioluminescence needs mi
Externí odkaz:
https://doaj.org/article/0d69a5d0faf342fd8c1e610d6331c0b7