Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Wayne L. Chandler"'
Publikováno v:
Case Reports in Medicine, Vol 2009 (2009)
The primary function of recombinant activated factor VII (rFVIIa) is to increase thrombin formation which leads to increased fibrin and less “bleeding.” As a result, most of literature utilizes “bleeding” as the outcome measure with respect t
Externí odkaz:
https://doaj.org/article/a843024508484618b1f6869a5796a20b
Publikováno v:
Transfusion. 63:933-941
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f81bd4295e20fc15da8eac681d90de30
https://doi.org/10.1111/trf.17246
https://doi.org/10.1111/trf.17246
Autor:
Rida A Hasan, Jennifer Pak, Christa Jefferis Kirk, Joshua M Friedland-Little, Wayne L Chandler
Publikováno v:
American Journal of Clinical Pathology. 159:60-68
Objectives Activated partial thromboplastin time (aPTT) is the primary test used to monitor intravenous (IV) direct thrombin inhibitors (DTIs) but has many limitations. The plasma diluted thrombin time (dTT) has shown better correlation with DTI leve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c588dccc5ccf3b53b992f68e91da5c2e
https://doi.org/10.1093/ajcp/aqac131
https://doi.org/10.1093/ajcp/aqac131
Autor:
Wayne L, Chandler
Publikováno v:
Thrombosis Research. 211:154-160
Extracorporeal membrane oxygenation (ECMO) can be life-saving, but suffers from thrombus formation in the circuit with associated risks of oxygenator occlusion, hemolysis and arterial embolism. The formation of thrombin is the key step to thrombus fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d58e02017dcaaa8e881f2507f5b759
https://doi.org/10.1016/j.thromres.2022.02.011
https://doi.org/10.1016/j.thromres.2022.02.011
Publikováno v:
ASAIO Journal. 68:1083-1092
Thrombosis in extracorporeal membrane oxygenation (ECMO) circuits remains a frequent complication. We characterize the location, extent, structure, and clinical implications of thrombi in 53 ECMO circuits from 46 pediatric patients. The tubing, pump,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf17594d01dcef81101e883fdbc6371
https://doi.org/10.1097/mat.0000000000001605
https://doi.org/10.1097/mat.0000000000001605
Autor:
Oksana Volod, Andrew J. Goodwin, Dong Chen, Huy P. Pham, James Alexander Isom, Karen A. Moser, John D. Olson, Russell A. Higgins, Amanda M. VanSandt, Kristi J. Smock, Geoffrey D. Wool, Thomas A. Long, Marian A. Rollins-Raval, Neil S Harris, Wayne L. Chandler
Publikováno v:
Archives of Pathology & Laboratory Medicine. 146:145-153
Context.— Assessing direct oral anticoagulant (DOAC) drug levels by reliable laboratory assays is necessary in a number of clinical scenarios. Objective.— To evaluate the performance of DOAC-specific assays for various concentrations of dabigatra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37318bb73f609ca8a2dde426bfe78bb
https://doi.org/10.5858/arpa.2020-0633-cp
https://doi.org/10.5858/arpa.2020-0633-cp
Publikováno v:
Artificial organsREFERENCES. 47(1)
Most pediatric patients show a decline in platelet counts while on extracorporeal life support (ECLS) and require multiple platelet transfusions. To better understand platelet loss during ECLS, this study estimated platelet loss rates due to diagnost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2626ba1dc61bc4090a7f87eb0b6a7ff
https://pubmed.ncbi.nlm.nih.gov/36056602
https://pubmed.ncbi.nlm.nih.gov/36056602
Autor:
David Michael McMullan, Wayne L. Chandler, Dana C. Matthews, Thomas V. Brogan, Christopher R. Burke, Larissa Yalon, Nabiha Huq Saifee
Publikováno v:
ASAIO Journal. 66:230-237
To balance the risk of bleeding versus circuit thrombosis during extracorporeal life support (ECLS), it is important to monitor anticoagulants and hemostasis. We evaluated the prothrombin time (PT), partial thromboplastin time (PTT), activated clotti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92eadd7dc323c3ec3b45748ed87cfec
https://doi.org/10.1097/mat.0000000000000993
https://doi.org/10.1097/mat.0000000000000993
Autor:
Russell A. Higgins, Wayne L. Chandler, Dong Chen, Oksana Volod, Kristi J. Smock, Karen A. Moser, Huy P. Pham, John D. Olson, Alan F. Brown
Publikováno v:
Archives of Pathology & Laboratory Medicine. 143:472-482
Context.—The College of American Pathologists (CAP) developed proficiency testing for platelet function assays by using blood collected by the participant added to challenge tubes containing either saline (normal) or tirofiban (abnormal).Objective.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c451241dd0da3770835464f87a478bfc
https://doi.org/10.5858/arpa.2017-0556-cp
https://doi.org/10.5858/arpa.2017-0556-cp
Platelet, Red Cell, and Endothelial Activation and Injury During Extracorporeal Membrane Oxygenation
Autor:
Wayne L. Chandler
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 67(8)
Extracorporeal membrane oxygenation (ECMO) can be lifesaving but suffers from high rates of bleeding and repeated transfusions. Current monitoring of blood cell damage during ECMO is limited to platelet counts, hematocrit, and plasma hemoglobin level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d39f3994428b02ba1f1aa1683bc4ef1
https://pubmed.ncbi.nlm.nih.gov/33606391
https://pubmed.ncbi.nlm.nih.gov/33606391