Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Wayne Johnston"'
Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Autor:
Jeroen Overman, Frank Fontaine, Mehdi Moustaqil, Deepak Mittal, Emma Sierecki, Natalia Sacilotto, Johannes Zuegg, Avril AB Robertson, Kelly Holmes, Angela A Salim, Sreeman Mamidyala, Mark S Butler, Ashley S Robinson, Emmanuelle Lesieur, Wayne Johnston, Kirill Alexandrov, Brian L Black, Benjamin M Hogan, Sarah De Val, Robert J Capon, Jason S Carroll, Timothy L Bailey, Peter Koopman, Ralf Jauch, Matthew A Cooper, Yann Gambin, Mathias Francois
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/631c7b6dffdc4c4b823c7ff82a631d2f
Autor:
Waleed M. Hussein, Phil M. Choi, Cheng Zhang, Wayne Johnston, Zhongfan Jia, Michael J. Monteiro, Mariusz Skwarczynski, Yann Gambin, Istvan Toth
Publikováno v:
AIMS Allergy and Immunology, Vol 2, Iss 3, Pp 141-147 (2018)
Despite the high safety profile of peptide-based vaccines over conventional counterparts, the inability of small peptides to produce a strong immune response represents the main obstacle for the development of these types of vaccines. Introducing a s
Externí odkaz:
https://doaj.org/article/cced61c6b9b24cb7aa2fc38e61aa8746
Autor:
Jeroen Overman, Frank Fontaine, Mehdi Moustaqil, Deepak Mittal, Emma Sierecki, Natalia Sacilotto, Johannes Zuegg, Avril AB Robertson, Kelly Holmes, Angela A Salim, Sreeman Mamidyala, Mark S Butler, Ashley S Robinson, Emmanuelle Lesieur, Wayne Johnston, Kirill Alexandrov, Brian L Black, Benjamin M Hogan, Sarah De Val, Robert J Capon, Jason S Carroll, Timothy L Bailey, Peter Koopman, Ralf Jauch, Matthew A Cooper, Yann Gambin, Mathias Francois
Publikováno v:
eLife, Vol 6 (2017)
Pharmacological targeting of transcription factors holds great promise for the development of new therapeutics, but strategies based on blockade of DNA binding, nuclear shuttling, or individual protein partner recruitment have yielded limited success
Externí odkaz:
https://doaj.org/article/1f3cf6e6ad3345a2bb95b0d0d5a753be
Autor:
Zhong Guo, Wayne Johnston, Oleksiy Kovtun, Sergey Mureev, Cornelia Bröcker, Christian Ungermann, Kirill Alexandrov
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/cc3ea7f873004993865e1ba775748f79
Autor:
Yann Gambin, Nicholas Ariotti, Kerrie-Ann McMahon, Michele Bastiani, Emma Sierecki, Oleksiy Kovtun, Mark E Polinkovsky, Astrid Magenau, WooRam Jung, Satomi Okano, Yong Zhou, Natalya Leneva, Sergey Mureev, Wayne Johnston, Katharina Gaus, John F Hancock, Brett M Collins, Kirill Alexandrov, Robert G Parton
Publikováno v:
eLife, Vol 3 (2014)
In mammalian cells three closely related cavin proteins cooperate with the scaffolding protein caveolin to form membrane invaginations known as caveolae. Here we have developed a novel single-molecule fluorescence approach to directly observe interac
Externí odkaz:
https://doaj.org/article/3222892030ff4bd78593681b9cee2d10
Autor:
Zhong Guo, Wayne Johnston, Oleksiy Kovtun, Sergey Mureev, Cornelia Bröcker, Christian Ungermann, Kirill Alexandrov
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81534 (2013)
Biochemical and structural analysis of macromolecular protein assemblies remains challenging due to technical difficulties in recombinant expression, engineering and reconstitution of multisubunit complexes. Here we use a recently developed cell-free
Externí odkaz:
https://doaj.org/article/73bac016548f4849a6b0e24e9d6b2efd
Autor:
Wayne Johnston
Publikováno v:
Partnership: The Canadian Journal of Library and Information Practice and Research, Vol 7, Iss 2 (2012)
The first in a series of two articles dealing with digital preservation, this article discusses repositories, more specifically Trusted Digital Repositories (TDR) and Research Data Repositories. The focus will be on the TDRs at Scholars Portal and Li
Externí odkaz:
https://doaj.org/article/35f8f435c7b04237a176b33af430f2a8
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14388 (2010)
The adaptation of organisms to a parasitic life style is often accompanied by the emergence of novel biochemical pathways absent in free-living organisms. As a result, the genomes of specialized parasitic organisms often code for a large number (>50%
Externí odkaz:
https://doaj.org/article/b87ae87dda1d466d9656f9c7b94a89cc
Autor:
Abdulmajeed Altoijry, Lindsay, Thomas F., K. Wayne Johnston, Mamdani, Muhammad, Al-Omran, Mohammed
Supplemental material, sj-pdf-1-imr-10.1177_0300060520987728 for Vascular injury-related in-hospital mortality in Ontario between 1991 and 2009 by Abdulmajeed Altoijry, Thomas F. Lindsay, K. Wayne Johnston, Muhammad Mamdani and Mohammed Al-Omran in J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186b1509d27eec6b33b5b262772d08ae
Autor:
Mohammed Al-Omran, Abdulmajeed Altoijry, K. Wayne Johnston, Muhammad Mamdani, Thomas F. Lindsay
Publikováno v:
Journal of International Medical Research, Vol 49 (2021)
The Journal of International Medical Research
The Journal of International Medical Research
Objective Trauma-related vascular injuries are major contributors to morbidity and mortality worldwide. We conducted a retrospective, population-based, cross-sectional study to examine temporal trends and factors associated with traumatic vascular in