Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wayne J Higgins"'
Autor:
Pieter J A de Koning, J Alain Kummer, Stefanie A H de Poot, Razi Quadir, Roel Broekhuizen, Anne F McGettrick, Wayne J Higgins, Bart Devreese, D Margaret Worrall, Niels Bovenschen
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e22645 (2011)
Granzyme-mediated cell death is the major pathway for cytotoxic lymphocytes to kill virus-infected and tumor cells. In humans, five different granzymes (i.e. GrA, GrB, GrH, GrK, and GrM) are known that all induce cell death. Expression of intracellul
Externí odkaz:
https://doaj.org/article/33f3842d8dc145ba90e0a342d9af5d7d
Autor:
Sergio Anguissola, William J McCormack, Michelle A Morrin, Wayne J Higgins, Denise M Fox, D Margaret Worrall
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26234 (2011)
PEDF (Pigment epithelium-derived factor) is a non-inhibitory member of the serpin gene family (serpinF1) that displays neurotrophic and anti-angiogenic properties. PEDF contains a secretion signal sequence, but although originally regarded as a secre
Externí odkaz:
https://doaj.org/article/614c246c36bb415cb6c5686363351eaf
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics. 1865(2)
SerpinI2/Pancpin/MEPI is a 46kDa member of the serpin (serine protease inhibitor) superfamily. It is downregulated in pancreatic and breast cancer, and associated with acinar cell apoptosis and pancreatic insufficiency when absent in mice. However, t
Autor:
Bart Devreese, Razi Quadir, Stefanie A. H. de Poot, D. Margaret Worrall, Anne F. McGettrick, Wayne J. Higgins, Niels Bovenschen, Pieter J.A. de Koning, Roel Broekhuizen, J. Alain Kummer
Publikováno v:
PLoS ONE
PLOS ONE
PLoS ONE, Vol 6, Iss 8, p e22645 (2011)
PLOS ONE
PLoS ONE, Vol 6, Iss 8, p e22645 (2011)
Granzyme-mediated cell death is the major pathway for cytotoxic lymphocytes to kill virus-infected and tumor cells. In humans, five different granzymes (i.e. GrA, GrB, GrH, GrK, and GrM) are known that all induce cell death. Expression of intracellul
Autor:
Michelle A. Morrin, William McCormack, Denise M. Fox, Sergio Anguissola, Wayne J. Higgins, D. Margaret Worrall
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26234 (2011)
PLoS ONE
PLoS ONE
PEDF (Pigment epithelium-derived factor) is a non-inhibitory member of the serpin gene family (serpinF1) that displays neurotrophic and anti-angiogenic properties. PEDF contains a secretion signal sequence, but although originally regarded as a secre
Publikováno v:
The Journal of biological chemistry. 285(6)
The glycosaminoglycan heparin is known to possess antimetastatic activity in experimental models and preclinical studies, but there is still uncertainty over its mechanism of action in this respect. As an anticoagulant, heparin enhances inhibition of