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pro vyhledávání: '"Wayne Hao"'
Autor:
Michael E. Dodge, Wayne Hao, Jessica A. Kilgore, Wei Tang, Baozhi Chen, Chuo Chen, Michael G. Roth, Lawrence G. Lum, James F. Amatruda, Jianming Lu, Zhiqiang Ma, Noelle S. Williams, Shuguang Wei, Chih Wei Fan
Publikováno v:
Nature chemical biology
The pervasive influence of secreted Wnt signaling proteins in tissue homeostasis and tumorigenesis has galvanized efforts to identify small molecules that target Wnt-mediated cellular responses. By screening a diverse synthetic chemical library, we h
Publikováno v:
ChemInform. 39
To identify novel inhibitors of tyrosinase, a fluorescent assay was developed which is suitable for high-throughput screening. In the assay, oxidation of the substrate by tyrosinase leads to the release of a fluorescent coumarin. Several small molecu
Publikováno v:
Bioorganicmedicinal chemistry letters. 17(24)
To identify novel inhibitors of tyrosinase, a fluorescent assay was developed which is suitable for high-throughput screening. In the assay, oxidation of the substrate by tyrosinase leads to the release of a fluorescent coumarin. Several small molecu