Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wayne Guida"'
Autor:
Heng Liu, Yunpeng Cui, Xue Zhao, Lulu Wei, Xudong Wang, Ning Shen, Odom, Timothy, Xuming Li, Lawless, William, Karunarathne, Kanchana, Muschol, Martin, Wayne Guida, Chuanhai Cao, Libin Ye, Jianfeng Cai
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 2/6/2024, Vol. 121 Issue 6, p1-10, 44p
Autor:
W. Douglas Cress, Wayne Guida, Harshani Lawrence, Shen-Shu Sung, Sandhya Boyapalle, Courtney A. Kurtyka, Yihong Ma
HLM006474 was identified using a computer-based virtual screen and the known crystal structure of the DNA-bound E2F4/DP2 heterodimer. Treatment of multiple cell lines with HLM006474 resulted in the loss of intracellular E2F4 DNA-binding activity as m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5836b43ebf5da86ddda3f2a01a842ba3
https://doi.org/10.1158/0008-5472.c.6497165
https://doi.org/10.1158/0008-5472.c.6497165
Autor:
W. Douglas Cress, Wayne Guida, Harshani Lawrence, Shen-Shu Sung, Sandhya Boyapalle, Courtney A. Kurtyka, Yihong Ma
Supplementary Figures 1-5, Methods and Materials from A Small-Molecule E2F Inhibitor Blocks Growth in a Melanoma Culture Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54f3bb04bd51ab32918323e90308f035
https://doi.org/10.1158/0008-5472.22373663
https://doi.org/10.1158/0008-5472.22373663
Autor:
Jared Tur, Sachin L. Badole, Ravikumar Manickam, Kalyan C. Chapalamadugu, Wanling Xuan, Wayne Guida, Jaret J. Crews, Kirpal S. Bisht, Srinivas M. Tipparaju
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 382(2)
Diabetes is associated with increased cardiac injury and sudden death. Nicotinamide phosphoribosyltransferase (Nampt) is an essential enzyme for the NAD
Autor:
Miguel, Burgos, Reginald, Philippe, Fabrice, Antigny, Paul, Buscaglia, Emmanuelle, Masson, Sreya, Mukherjee, Pauline, Dubar, Cédric, Le Maréchal, Florence, Campeotto, Nicolas, Lebonvallet, Maud, Frieden, Juan, Llopis, Beatriz, Domingo, Peter B, Stathopulos, Mitsuhiko, Ikura, Wesley, Brooks, Wayne, Guida, Jian-Min, Chen, Claude, Ferec, Thierry, Capiod, Olivier, Mignen
Publikováno v:
Journal of cell science. 134(3)
Since deregulation of intracellular Ca
Autor:
Afua Adutwumwa Akuffo, Aileen Alontaga, Rainer Metclaf, Matthew S Beatty, Jessica McDaniel, Steven Gunawan, Muhammad Ayaz, Andreas Becker, Rebecca S Hesterberg, William E Goodheart, Yan Yang, Kenyon G Daniel, Ernst Schonbrunn, Wayne Guida, Harshani Lawrence, Nicholas Lawrence, Pearlie Epling-Burnette
Publikováno v:
The Journal of Immunology. 198:52.18-52.18
Protein degraders have been developed that can aide in understanding gene function. These chemicals contain complementary bifunctional components that 1) interact with specific proteins, and 2) engage an E3 ligase which leads to polyubiquitination an