Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Wayne G. Carter"'
Publikováno v:
Antioxidants, Vol 13, Iss 8, p 932 (2024)
The transition metal cadmium (Cd) is toxic to humans and can induce cellular redox stress and inflammation. Cd is a recognized carcinogen, but the molecular mechanisms associated with its genotoxicity and carcinogenicity are not defined. Therefore, a
Externí odkaz:
https://doaj.org/article/e5dd1177ffca426babe2fd8a340b9937
Publikováno v:
Brain Sciences, Vol 14, Iss 6, p 545 (2024)
Epilepsy is a neurological disease that affects approximately 50 million people worldwide. Despite an existing abundance of antiepileptic drugs, lifelong disease treatment is often required but could be improved with alternative drugs that have fewer
Externí odkaz:
https://doaj.org/article/9cc338477de44b498a5cfda63fe965e4
Autor:
Anusha W. Mudyanselage, Buddhika C. Wijamunige, Artur Kocoń, Ricky Turner, Denise McLean, Benito Morentin, Luis F. Callado, Wayne G. Carter
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 580 (2024)
Alcohol is toxic to neurons and can trigger alcohol-related brain damage, neuronal loss, and cognitive decline. Neuronal cells may be vulnerable to alcohol toxicity and damage from oxidative stress after differentiation. To consider this further, the
Externí odkaz:
https://doaj.org/article/d118e697237a4f46bd1a9ba5132819ff
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 1, Pp 12-32 (2022)
COVID-19 disease has had a global impact on human health with increased levels of morbidity and mortality. There is an unmet need to design and produce effective antivirals to treat COVID-19. This study aimed to explore the potential ability of natur
Externí odkaz:
https://doaj.org/article/20bd75f50e6049cca3b966d7ed0c363b
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 505 (2024)
Mefloquine (MQ) is a quinoline-based anti-malarial drug used for chemoprophylaxis or as a treatment in combination with artesunate. Although MQ has clear anti-Plasmodium falciparum properties, it can induce neurotoxicity and undesired neuropsychiatri
Externí odkaz:
https://doaj.org/article/d9f07d5516424c9d994058486121e2ab
Autor:
Ekramy Elmorsy, Ayat Al-Ghafari, Huda Al Doghaither, Sara Hashish, Mohamed Salama, Anusha W. Mudyanselage, Lipta James, Wayne G. Carter
Publikováno v:
Brain Sciences, Vol 13, Iss 12, p 1717 (2023)
Paraquat (PQ), rotenone (RO), and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) are neurotoxicants that can damage human health. Exposure to these neurotoxicants has been linked to neurodegeneration, particularly Parkinson’s disease. However,
Externí odkaz:
https://doaj.org/article/4faf699625ed432da4bcdd9f0bf1d445
Publikováno v:
Brain Sciences, Vol 13, Iss 5, p 728 (2023)
Organophosphate (OP) and carbamate pesticides are toxic to pests through targeted inhibition of acetylcholinesterase (AChE). However, OPs and carbamates may be harmful to non-target species including humans and could induce developmental neurotoxicit
Externí odkaz:
https://doaj.org/article/ceb8e78c8a22473aada208825e4754e2
Autor:
Maryam N. ALNasser, Ayman M. AlSaadi, Alison Whitby, Dong-Hyun Kim, Ian R. Mellor, Wayne G. Carter
Publikováno v:
Life, Vol 13, Iss 4, p 1019 (2023)
Aberrant accumulation of the neurotransmitter L-glutamate (L-Glu) has been implicated as a mechanism of neurodegeneration, and the release of L-Glu after stroke onset leads to a toxicity cascade that results in neuronal death. The acai berry (Euterpe
Externí odkaz:
https://doaj.org/article/2375535ba15b42808b9a04dc717d4749
Publikováno v:
Molecules, Vol 27, Iss 15, p 4891 (2022)
Alzheimer’s disease (AD) is characterised by progressive neuronal atrophy and the loss of neuronal function as a consequence of multiple pathomechanisms. Current AD treatments primarily operate at a symptomatic level to treat a cholinergic deficien
Externí odkaz:
https://doaj.org/article/c83c21c3dfe4400c863bea8267e026fc
Publikováno v:
Brain Sciences, Vol 12, Iss 8, p 975 (2022)
Acute or chronic exposures to pesticides have been linked to neurotoxicity and the potential development of neurodegenerative diseases (NDDs). This study aimed to consider the neurotoxicity of three widely utilized pesticides: malathion, chlorpyrifos
Externí odkaz:
https://doaj.org/article/237c8437135d479f8696e150780654bc