Zobrazeno 1 - 10
of 143
pro vyhledávání: '"Wayne F, Patton"'
Autor:
Wayne F. Patton
Publikováno v:
BioTechniques, Vol 28, Iss 5, Pp 944-957 (2000)
Proteomics investigations endeavor to provide a global understanding of gene product synthesis rate, degradation rate, functional competence, posttranslational modification, subcellular distribution and physical interactions with other cell component
Externí odkaz:
https://doaj.org/article/1ad3ea4fc2cd419784b2c5f5395395a3
Publikováno v:
BioTechniques, Vol 21, Iss 5, Pp 888-897 (1996)
Recently, we developed reversible metal chelate stains that are fully compatible with immunoblotting and protein sequencing. Membrane supports are incubated in Ferrozine®/ferrous complex followed by ferrocyanide/ferric complex (double-metal chelate
Externí odkaz:
https://doaj.org/article/eb3540a1afb04f8ebafac44ce02b0411
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22429 (2011)
An underlying mechanism for multi drug resistance (MDR) is up-regulation of the transmembrane ATP-binding cassette (ABC) transporter proteins. ABC transporters also determine the general fate and effect of pharmaceutical agents in the body. The three
Externí odkaz:
https://doaj.org/article/fe7c234b4f1140f7bfa0d99a79aa075b
Publikováno v:
Histochemistry and Cell Biology. 139:659-670
Autophagic and endo-lysosomal degradative pathways are essential for cell homeostasis. Availability of reliable tools to interrogate these pathways is critical to unveil their involvement in physiology and pathophysiology. Although several probes hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f782ece01553722321b767b6b2e86db
https://doi.org/10.1007/s00418-012-1057-6
https://doi.org/10.1007/s00418-012-1057-6
Autor:
Jean Qiu, Bo Lin, Dmitry Kuksin, Ning Lai, Wayne F. Patton, Eric Chan, Dee Shen, Leo Li-Ying Chan, Alisha R. Wilkinson
Publikováno v:
Autophagy. 8:1371-1382
Autophagy is an important cellular catabolic process that plays a variety of important roles, including maintenance of the amino acid pool during starvation, recycling of damaged proteins and organelles, and clearance of intracellular microbes. Curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a8aad29cf4c59f1afb35da1e8b35c9
https://doi.org/10.4161/auto.21028
https://doi.org/10.4161/auto.21028
Autor:
Paul W. Sheppard, Lijun Dai, Wayne F. Patton, Dee Shen, Thomas P. Nicholson, Eric Chan, Jack Coleman
Publikováno v:
Cell Biochemistry and Biophysics
Aggresomes and related inclusion bodies appear to serve as storage depots for misfolded and aggregated proteins within cells, which can potentially be degraded by the autophagy pathway. A homogenous fluorescence-based assay was devised to detect aggr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::372cc14fb6ec29baab19c12d693ac751
http://europepmc.org/articles/PMC3112480
http://europepmc.org/articles/PMC3112480
Publikováno v:
Microscopy Today. 17:18-21
The nucleolus represents a highly dynamic nuclear domain arising from an equilibrium between the level of ribosomal RNA synthesis and the efficiency of ribosomal RNA processing [1, 2]. Although the nucleolus is primarily associated with ribosome biog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9cf153b06e15a18685302c201aed53e
https://doi.org/10.1017/s1551929509000066
https://doi.org/10.1017/s1551929509000066
Autor:
Dee Shen, Leo Li-Ying Chan, Jean Qiu, Ning Lai, Dmitry Kuksin, Wayne F. Patton, Alisha R. Wilkinson, Eric Chun Yong Chan, Bo Lin
Autophagy is a highly regulated and complex process that plays an important role in cellular functions such as maintaining the amino acid pool during starvation, recycling of damaged proteins and organelles, and clearing intracellular microbes. The c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8c4cf5e8ea7f3c899d95a4b63f54886
https://doi.org/10.1016/b978-0-12-805421-5.00008-2
https://doi.org/10.1016/b978-0-12-805421-5.00008-2
Autor:
Linan Song, Ira S. Krull, Alvydas Mikulskis, Mei Wang, Elaine Scrivener, Venkateswarlu Panchagnula, Wayne F. Patton, Heinz-Emil-Hauck, Eva Golenko, Michael Schulz, Yang Wang, Tanya Knubovets
Publikováno v:
Journal of Chromatography A. 1155:112-123
A novel strategy is presented for the fractionation of complex peptide mixtures using two-dimensional planar electrochromatography/thin-layer chromatography (2D PEC/TLC). Phosphopeptides migrate more slowly in the first dimension, based upon their an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a81c3c8ec0b6f452f9dcb5d73a2fa44d
https://doi.org/10.1016/j.chroma.2007.04.029
https://doi.org/10.1016/j.chroma.2007.04.029
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 29:1177-1218
Planar electrochromatography (PEC) and thin‐layer electrophoresis (TLE) are examined for their potential application to peptide and protein analysis, employing one‐dimensional (1D) and two‐dimensional (2D) separations, which could potentially b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20d60dd584a2ec0838db04fb96fbd624
https://doi.org/10.1080/10826070600574978
https://doi.org/10.1080/10826070600574978