Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wayne A. Little"'
Autor:
Michael A. Blanar, Fouad Shalaby, Paul Levesque, Wen-Pin Yang, Wayne A. Little, Mary Lee Conder, Tonya Jenkins-West
Publikováno v:
Circulation. 96:1733-1736
Background Mutations that map to the KvLQT1 gene on human chromosome 11 account for more than 50% of inherited long QT syndrome (LQTS). It has been discovered recently that the KvLQT1 and minK proteins functionally interact to generate a current with
Autor:
Michael A. Blanar, Wayne A. Little, Fouad Shalaby, Paul C. Levesque, Wen-Pin Yang, Mary Lee Conder
Publikováno v:
Proceedings of the National Academy of Sciences. 94:4017-4021
The clinical features of long QT syndrome result from episodic life-threatening cardiac arrhythmias, specifically the polymorphic ventricular tachycardia torsades de pointes. KVLQT1 has been established as the human chromosome 11-linked gene responsi
Autor:
William A. Beard, Thomas A. Patterson, Steven G. Widen, Xinbo Cheng, Samuel H. Wilson, Wayne A Little, Amalendra Kumar
Publikováno v:
Protein expression and purification. 18(1)
The cDNA encoding the human polymerase β from HeLa cells was PCR amplified and cloned, and its nucleotide sequence determined. The DNA sequence is identical to the polymerase β cDNA sequence from Tera-2 cells. Three expression strategies were emplo
Publikováno v:
Mutation research. 406(1)
Sequencing of a human DNA ligase I cDNA clone derived from HeLa cells revealed two unreported differences with the published sequence: a single base change and a three-base deletion. Both differences are in exon 6, and were analyzed by amplifying a s
Autor:
Paul Levesque, Wen-Pin Yang, Pankajavalli Ramakrishnan, Michael G. Neubauer, Wayne A. Little, Mary Lee Conder, Michael A. Blanar
Publikováno v:
The Journal of biological chemistry. 273(31)
Benign familial neonatal convulsions (BFNC), a class of idiopathic generalized epilepsy, is an autosomal dominantly inherited disorder of newborns. BFNC has been linked to mutations in two putative K+ channel genes, KCNQ2 and KCNQ3. Amino acid sequen
Autor:
Wayne A. Little, Cort S. Madsen, Fouad Shalaby, Nick C. Trippodo, Michael A. Blanar, Balkrushna C. Panchal, Feng-Lai Wang, Lindsey B. Ciali, Brian Patton, David W. Green, Patricia A. Ferrer, Kara B. Anthony
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:A109
Publikováno v:
Journal of Periodontology. 58:628-633
This investigation monitored the effects of daily oral rinses with octenidine on plaque and gingivitis in five monkeys. Formulations containing 0.5% or 1.0% octenidine or the rinse vehicle placebo were provided daily for 2 weeks. Each week the dentit
Publikováno v:
Journal of cellular physiology. 139(1)
Properties of the change from asparagine dependence (asn-) to independence (asn+) were investigated in the androgenetic haploid frog cell line ICR 2A. Two types of asn+ variants arose spontaneously during culture. Glutamine-dependent asparagine synth