Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Wayne, Croft"'
Autor:
Kriti Verma, Wayne Croft, David Greenwood, Christine Stephens, Ram Malladi, Jane Nunnick, Jianmin Zuo, Francesca A. M. Kinsella, Paul Moss
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Allogeneic stem cell transplantation is used widely in the treatment of hematopoietic malignancy although graft versus host disease and relapse remain major complications. We measured the serum protein expression of 92 inflammation-related markers fr
Externí odkaz:
https://doaj.org/article/ac484c2833d34430a3caed6540d022b0
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-17 (2022)
Abstract Immune checkpoint blockade has recently proven effective in subsets of patients with esophageal adenocarcinoma (EAC) but little is known regarding the EAC immune microenvironment. We determined the single cell transcriptional profile of EAC
Externí odkaz:
https://doaj.org/article/c0a86efdcadf43ae935c60ee085be82d
Autor:
Wayne Croft, Hayden Pearce, Sandra Margielewska-Davies, Lindsay Lim, Samantha M Nicol, Fouzia Zayou, Daniel Blakeway, Francesca Marcon, Sarah Powell-Brett, Brinder Mahon, Reena Merard, Jianmin Zuo, Gary Middleton, Keith Roberts, Rachel M Brown, Paul Moss
Publikováno v:
eLife, Vol 12 (2023)
Pancreatic ductal adenocarcinoma has a poor clinical outcome and responses to immunotherapy are suboptimal. Stromal fibroblasts are a dominant but heterogenous population within the tumor microenvironment and therapeutic targeting of stromal subsets
Externí odkaz:
https://doaj.org/article/d7357419260341daa6df22adc8ce75ad
Autor:
Kriti Verma, Wayne Croft, Hayden Pearce, Jianmin Zuo, Christine Stephens, Jane Nunnick, Francesca AM Kinsella, Ram Malladi, Paul Moss
Publikováno v:
Haematologica, Vol 108, Iss 2 (2022)
Allogeneic stem cell transplantation is used widely in the treatment of hematopoietic malignancy. However, relapse of malignant disease is the primary cause of treatment failure and reflects loss of immunological graft-versus-leukemia effect. We stud
Externí odkaz:
https://doaj.org/article/f2711c63e9e549aa9e62022cb1ca36b0
Autor:
Helen M Parry, Alexander C Dowell, Jianmin Zuo, Kriti Verma, Francesca A M Kinsella, Jusnara Begum, Wayne Croft, Archana Sharma-Oates, Guy Pratt, Paul Moss
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009349 (2021)
PD-1 is expressed on exhausted T cells in cancer patients but its physiological role remains uncertain. We determined the phenotype, function and transcriptional correlates of PD-1 expression on cytomegalovirus-specific CD4+ T cells during latent inf
Externí odkaz:
https://doaj.org/article/24af3b309b9e44e4abf6cd1d20def486
Autor:
Hayden Pearce, Wayne Croft, Samantha M. Nicol, Sandra Margielewska-Davies, Richard Powell, Richard Cornall, Simon J. Davis, Francesca Marcon, Matthew R. Pugh, Éanna Fennell, Sarah Powell-Brett, Brinder S. Mahon, Rachel M. Brown, Gary Middleton, Keith Roberts, Paul Moss
Publikováno v:
Cancer Immunology Research. 11:435-449
Pancreatic ductal adenocarcinoma (PDAC) has a poor clinical outlook. Responses to immune checkpoint blockade are suboptimal and a much more detailed understanding of the tumor immune microenvironment is needed if this situation is to be improved. Her
Autor:
Guido Frumento, Kriti Verma, Wayne Croft, Andrea White, Jianmin Zuo, Zsuzsanna Nagy, Stephen Kissane, Graham Anderson, Paul Moss, Frederick E. Chen
Publikováno v:
iScience, Vol 23, Iss 4, Pp - (2020)
Summary: Primary stimulation of T cells is believed to trigger unidirectional differentiation from naive to effector and memory subsets. Here we demonstrate that IL-7 can drive the phenotypic reversion of recently differentiated human central and eff
Externí odkaz:
https://doaj.org/article/032e2ffed9dc456faae1222f16ffd34e
Autor:
Guido Frumento, Jianmin Zuo, Kriti Verma, Wayne Croft, Pradeep Ramagiri, Frederick E. Chen, Paul Moss
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
CD117 (cKit) is the receptor for stem cell factor (SCF) and plays an important role in early haemopoiesis. We show that CD117 is also expressed following priming of mature human CD8+ T cells in vitro and is detectable following primary infection in v
Externí odkaz:
https://doaj.org/article/487493eab05d4f91a570276e70e86371
Autor:
Paul Moss, Keith Roberts, Gary Middleton, Rachel M. Brown, Brinder S. Mahon, Sarah Powell-Brett, Éanna Fennell, Matthew R. Pugh, Francesca Marcon, Simon J. Davis, Richard Cornall, Richard Powell, Sandra Margielewska-Davies, Samantha M. Nicol, Wayne Croft, Hayden Pearce
Supplementary Figures S1 - S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e42f4ba5f8a45010341e7e26126c08b
https://doi.org/10.1158/2326-6066.22551825.v1
https://doi.org/10.1158/2326-6066.22551825.v1
Autor:
Paul Moss, Keith Roberts, Gary Middleton, Rachel M. Brown, Brinder S. Mahon, Sarah Powell-Brett, Éanna Fennell, Matthew R. Pugh, Francesca Marcon, Simon J. Davis, Richard Cornall, Richard Powell, Sandra Margielewska-Davies, Samantha M. Nicol, Wayne Croft, Hayden Pearce
Supplementary Tables 1 - 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e74e530824afb1115fdefea5b5c60d5
https://doi.org/10.1158/2326-6066.22551822.v1
https://doi.org/10.1158/2326-6066.22551822.v1