Zobrazeno 1 - 10
of 602
pro vyhledávání: '"Wave ripple"'
Autor:
YANG Danyang, ZHANG Weiwei
Publikováno v:
陆军军医大学学报, Vol 46, Iss 16, Pp 1874-1881 (2024)
Objective To investigate the changes and features of firing activities of interneurons in dorsal hippocampus during the acquisition and consolidation of associative memory. Methods Trace eyeblink conditioning (tEBC) was utilized as a behavioral model
Externí odkaz:
https://doaj.org/article/38eba19714f34eec8b7c27ac6f466bc2
Publikováno v:
陆军军医大学学报, Vol 45, Iss 24, Pp 2495-2502 (2023)
Objective To investigate the difference of dentate gyrus (DG) neuronal activity between wakefulness and sleep state, and the characteristics of DG neuronal activity during hippocampal sharp wave ripple and θ oscillations. Methods Six 3-month-dd male
Externí odkaz:
https://doaj.org/article/a110fd250b8b4b8987011a2df77ef42a
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 2, Pp 136-143 (2023)
Biased memory processing contributes to the development and exacerbation of depression, and thus could represent a potential therapeutic target for stress-induced mental disorders. Synchronized spikes in hippocampal neurons, corresponding to sharp wa
Externí odkaz:
https://doaj.org/article/ac17bbbf14454f0e83100b14df5e1ff1
Autor:
Leonidas J. Leontiadis, George Trompoukis, Giota Tsotsokou, Athina Miliou, Panagiotis Felemegkas, Costas Papatheodoropoulos
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Fragile X syndrome (FXS) is a genetic neurodevelopmental disorder characterized by intellectual disability and is related to autism. FXS is caused by mutations of the fragile X messenger ribonucleoprotein 1 gene (Fmr1) and is associated with alterati
Externí odkaz:
https://doaj.org/article/786956d116b74a478e4b3d319d979b93
Publikováno v:
Brain Research Bulletin, Vol 187, Iss , Pp 181-198 (2022)
Sleep abnormalities are widely reported in patients with Alzheimer’s disease (AD) and are linked to cognitive impairments. Sleep abnormalities could be potential biomarkers to detect AD since they are often observed at the preclinical stage. Moreov
Externí odkaz:
https://doaj.org/article/eafd97115a5949df9ee4c28a9ef2c631
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Alzheimer’s disease (AD) is a severe neurodegenerative disorder caused by the accumulation of toxic proteins, amyloid-beta (Aβ) and tau, which eventually leads to dementia. Disease-modifying therapies are still lacking, due to incomplete insights
Externí odkaz:
https://doaj.org/article/6931e74a6c884b87892ab829b03e5da6
Inhibition is a prevalent mode of activity in the neocortex around awake hippocampal ripples in mice
Publikováno v:
eLife, Vol 12 (2023)
Coordinated peri-ripple activity in the hippocampal-neocortical network is essential for mnemonic information processing in the brain. Hippocampal ripples likely serve different functions in sleep and awake states. Thus, the corresponding neocortical
Externí odkaz:
https://doaj.org/article/924fdffa35ba468786103704aebc9906
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Dravet Syndrome (DS) is a genetic, infantile-onset epilepsy with refractory seizures and severe cognitive impairment. While network level pathophysiology is poorly understood, work in genetic mouse models of DS reveals selective reduction of inhibito
Externí odkaz:
https://doaj.org/article/8f1a1a5fe0fc4beb94c277fb08d03d9b