Výsledky vyhledávání - "Watts, George"

Akademický článek

DNA methylation changes in ovarian cancer are cumulative with disease progression and identify tumor stage

Autor: Watts, George, Futscher, Bernard, Holtan, Nicholas, DeGeest, Koen, Domann, Frederick, Rose, Stephen

BACKGROUND:Hypermethylation of promoter CpG islands with associated loss of gene expression, and hypomethylation of CpG-rich repetitive elements that may destabilize the genome are common events in most, if not all, epithelial cancers.METHODS:The met

Externí odkaz: http://hdl.handle.net/10150/610037
http://arizona.openrepository.com/arizona/handle/10150/610037

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Akademický článek

Performance evaluation of commercial short-oligonucleotide microarrays and the impact of noise in making cross-platform correlations

Autor: Shippy, Richard, Sendera, Timothy, Lockner, Randall, Palaniappan, Chockalingam, Kaysser-Kranich, Tamma, Watts, George, Alsobrook, John

BACKGROUND:Despite the widespread use of microarrays, much ambiguity regarding data analysis, interpretation and correlation of the different technologies exists. There is a considerable amount of interest in correlating results obtained between diff

Externí odkaz: http://hdl.handle.net/10150/610395
http://arizona.openrepository.com/arizona/handle/10150/610395

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Dissertation/ Thesis

The role of 5-methylcytosine in the expression of O(6)-methylguanine DNA-methyltransferase

Autor: Watts, George Somerset, 1971

Regulation of the gene which encodes the human DNA repair enzyme O6-methylguanine DNA methyltransferase (MGMT) is of clinical interest and provides a gene model for the study of CpG methylation's role in transcriptional regulation. Expression of MGMT

Externí odkaz: http://hdl.handle.net/10150/282599

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