Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Watthey Jeffrey W H"'
Autor:
Watthey Jeffrey W H, James L. Stanton
Publikováno v:
Chemistry of Heterocyclic Compounds: Azepines, Part 2, Volume 43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dac116515eb19bda6b5613555ce10b8
https://doi.org/10.1002/9780470187227.ch1
https://doi.org/10.1002/9780470187227.ch1
Autor:
Watthey Jeffrey W H, Mahesh Desai
Publikováno v:
The Journal of Organic Chemistry. 47:1755-1759
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5bc3aa0076793ae17554a485bdeab7
https://doi.org/10.1021/jo00348a032
https://doi.org/10.1021/jo00348a032
Autor:
Mahesh Desai, Watthey Jeffrey W H, Barbara M. Finn, Joseph E. Babiarz, James L. Stanton, Hollis C. Tomaselli
Publikováno v:
Chemischer Informationsdienst. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73ce9fbbcec748c3d802c942e04805eb
https://doi.org/10.1002/chin.198609194
https://doi.org/10.1002/chin.198609194
Autor:
Mahesh Desai, Terrence Gavin, Watthey Jeffrey W H, Steven L. Patt, Ronald K. Rodebaugh, Barbara M. Finn
Publikováno v:
Journal of medicinal chemistry. 26(8)
The synthesis of two thiophene-containing analogues of mianserin, i.e., 1,2,3,4,10,13b-hexahydro-2-methylpiperazino[1,2-a]thieno[2, 3-c][1]benzazepine (2), and the corresponding [3,2-c] isomer (12) is described. The key step in the synthesis is the n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78ed43f9cec34f5f64ea5be322cc2a7d
https://pubmed.ncbi.nlm.nih.gov/6192241
https://pubmed.ncbi.nlm.nih.gov/6192241
Publikováno v:
Chemischer Informationsdienst. 11
The synthesis of an analogue of amiloride in which the acylguanidine moiety has been replaced by a 1,2,4-oxadiazol-3-amine unit is described. This substance (3, CGS 4270) exhibited a diuretic profile similar to that of amiloride when evaluated in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bbeb0fdca49efd220e1ec0e0782a588
https://doi.org/10.1002/chin.198042196
https://doi.org/10.1002/chin.198042196
Publikováno v:
Journal of medicinal chemistry. 28(10)
Syntheses of the potent angiotensin converting enzyme inhibitor (3S)-1-(carboxymethyl)-3-[[(1S)-1-carboxy-3-phenylpropyl]amino]- 2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one (4b; CGS 14831) and the related monoester prodrug (17a; CGS 14824A) are describ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2d3bcdd54c52f323baa9d4bac7e409
https://pubmed.ncbi.nlm.nih.gov/2995669
https://pubmed.ncbi.nlm.nih.gov/2995669
Publikováno v:
Chemischer Informationsdienst. 17
Wie im Formelschema angedeutet, werden die Verbindungen (III) und (XII) dargestellt und auf ACE (angiotensin converting enzyme)-inhibierende Wirkung gepruft.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5da9e3a1264f9f7d40d06f6c88222d52
https://doi.org/10.1002/chin.198606203
https://doi.org/10.1002/chin.198606203
Publikováno v:
Chemischer Informationsdienst. 15
Syntheses of the potent angiotensin converting enzyme inhibitor 1-(carboxymethyl)-3-(mercaptomethyl)-2,3,4,5-tetrahydro-1H-1- benzazep in -2-one (4a) and the corresponding eight-membered ring analogue (4b) are described. The influence of ring size on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5422d9268fa77e4ad92f5863a31c7bc6
https://doi.org/10.1002/chin.198444249
https://doi.org/10.1002/chin.198444249
Publikováno v:
Chemischer Informationsdienst. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e6c1bd83ecaa8a0226d4f7da701a56c
https://doi.org/10.1002/chin.198350197
https://doi.org/10.1002/chin.198350197