Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Watt Pc"'
Autor:
John H. Walsh, Stefan Moldovan, Watt Pc, Robert Kleinman, Thu-Ha Nguyen, Francis C. Brunicardi, Ronald L. Gingerich
Publikováno v:
Pancreas. 23:302-308
Introduction In this study, immunoneutralization of endogenous insulin, glucagon, and somatostatin with specific antibodies was used in an isolated perfused human pancreas (IPHP) model. Aims To study intrapancreatic cellular interactions and pancreat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e689d537a4333356b2bfb640dd5f671e
https://doi.org/10.1097/00006676-200110000-00012
https://doi.org/10.1097/00006676-200110000-00012
Autor:
Francis C. Brunicardi, Yoko Mullen, Watanabe Y, Elizabeth A. Stein, Watt Pc, Nomura Y, Hober C, Pierre Y. Benhamou
Publikováno v:
Pancreas. 14:199-204
Summary The availability of highly purified human islets has increased with the progressive improvement of isolation methods. This has provided opportunities to perform various in vitro studies on human islets. However, when islets are maintained in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2193f2d3c21c23c0c7b3cd23bbfd4d43
https://doi.org/10.1097/00006676-199703000-00014
https://doi.org/10.1097/00006676-199703000-00014
Autor:
Watt Pc, Yoko Mullen, Robert Kleinman, Edward Passaro, Satoshi Une, Seiji Arita, Peter G. Stock, Pierre Y. Benhamou, Takashi Kenmochi, Yoshi Wantanabe, L Shevlin, Yasu Nomura, F. Charles Brunicardi, Thomas J. Rosenthal, S. Ohtsuka, A. Atiya, Ronald W. Busuttil, Masaaki Miyamato
Publikováno v:
Surgery. 118:967-972
Background. The University of California Islet Transplant Consortium was formed to evaluate the feasibility of performing clinical islet transplantation at different transplant centers by using a single centralized islet isolation laboratory. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f37147cf60e32ca3cf08a03c5d1dc45
https://doi.org/10.1016/s0039-6060(05)80101-1
https://doi.org/10.1016/s0039-6060(05)80101-1
Autor:
Watt Pc, Watanabe Y, Pierre Y. Benhamou, Takashi Kenmochi, Nomura Y, Yoko Mullen, Brunicardi Fc, Elizabeth Stein, Masaaki Miyamoto, Christine Hober
Publikováno v:
Hormone and Metabolic Research. 27:113-120
Allograft rejection is the major cause for failure in clinical islet transplantation for diabetic patients. A reduction of donor islet immunogenicity is potentially a useful approach for altering recipient's immune responses. Studies in animal models
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b887246f31ad4b0a62edd4e0706ba2
https://doi.org/10.1055/s-2007-979921
https://doi.org/10.1055/s-2007-979921
Autor:
Christopher D. Anderson, Nomura Y, Watt Pc, Brunicardi Fc, Watanabe Y, Edward Passaro, Yoko Mullen, Michael J. Zinner
Publikováno v:
Journal of Surgical Research. 56:367-371
Work in rodents has shown that injection of pancreatic islets of Langerhans into the thymus can induce donor-specific unresponsiveness to islets subsequently transplanted to extrathymic sites. The overall objective of our investigation is to test thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c75df0263c7426272f0bab16ac58706
https://doi.org/10.1006/jsre.1994.1057
https://doi.org/10.1006/jsre.1994.1057
Autor:
Yoko Mullen, Ryozo Moriuchi, M. Watanabe, Shoichi Akazawa, Tsutomu Miyamoto, T. Yamaguchi, Brunicardi Fc, Watt Pc, S Nagataki, K. Saitoh, Eiji Kawasaki
Publikováno v:
Biochemical and Biophysical Research Communications. 192:1353-1359
Glutamic acid decarboxylase (GAD) catalyzes formation of γ-aminobutyric acid from glutamic acid and is a major autoantigen in insulin-dependent diabetes mellitus. Its two isoforms, GAD65 and GAD67, are encoded by two separate genes. We prepared huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8bffebe75281106e4da754b92dfef66
https://doi.org/10.1006/bbrc.1993.1565
https://doi.org/10.1006/bbrc.1993.1565
Autor:
Catia Sternini, Vay Liang W. Go, Howard Wong, Karl Anderson, J.H. Walsh, Watt Pc, R. De Giorgio, Howard A. Reber, A. L. Widdison, F. C. Brunicardi
Publikováno v:
Cell and Tissue Research. 269:447-458
In the pancreas, calcitonin gene-related peptide (CGRP) immunoreactivity has been described in nerve fibers and in distinct types of islet cells. This unique, apparently species-specific cell-type expression prompted the present investigation to clar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f4b76f7f57b92def6a947c82b58949
https://doi.org/10.1007/bf00353900
https://doi.org/10.1007/bf00353900
Publikováno v:
Pancreas. 9(2)
This study was undertaken to determine whether intraislet somatostatin inhibits insulin secretion in the human islet. A high-affinity monoclonal somatostatin antibody was used to immunoneutralize somatostatin in the isolated, perfused human pancreas.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45bf9a94300e64a2de0e9f052119ba6
https://pubmed.ncbi.nlm.nih.gov/7910686
https://pubmed.ncbi.nlm.nih.gov/7910686
Publikováno v:
American journal of surgery. 165(3)
The ability to transfer genetic material from one cell to another provides a novel approach for the investigation and potential treatment of a variety of diseases. Several gene transfer techniques have been developed. Of these, the use of retroviruse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73b1df6b7a2ce0760bbe63bc2553c9f1
https://pubmed.ncbi.nlm.nih.gov/8447541
https://pubmed.ncbi.nlm.nih.gov/8447541
Publikováno v:
American journal of surgery. 165(1)
Among a series of 107 closely followed patients with gastrinoma, 60 patients with sporadic type tumors were identified and evaluated. There were 44 patients (73%) with tumors to the right of the superior mesenteric artery (SMA). Of these, 16 (36%) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54a737a3ddef011937061b51057fc362
https://pubmed.ncbi.nlm.nih.gov/8093424
https://pubmed.ncbi.nlm.nih.gov/8093424