Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Watson B. Laughton"'
Autor:
Peter E. Grebow, Watson B. Laughton, George C. McCormick, S Gorman, S P King, Donna Simcoe, Y N Wong
Publikováno v:
The Journal of Clinical Pharmacology. 39:281-288
An open-label, single-center, single-dose, parallel-group study was performed in healthy young males and females as well as healthy elderly males to examine the influence of age and gender on the pharmacokinetics of modafinil following administration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c09daa8306a95c2a7cf3c9264d937dd3
https://doi.org/10.1177/009127009903900312
https://doi.org/10.1177/009127009903900312
Autor:
Peter E. Grebow, Watson B. Laughton, Y. Nancy Wong, George C. McCormick, Linda N. Hartman, S. Peter King, Donna Simcoe
Publikováno v:
The Journal of Clinical Pharmacology. 39:30-40
A randomized, double-blind, placebo-controlled, ascending-dose study was conducted to evaluate the pharmacokinetic and safety profiles of increasing modafinil doses (200 mg, 400 mg, 600 mg, 800 mg) administered orally over a 7-day period in normal he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4493357a686b5052ca3ed4a0b7da2b38
https://doi.org/10.1177/00912709922007534
https://doi.org/10.1177/00912709922007534
Autor:
Watson B. Laughton, Donna Simcoe, Yusong Chen, Linda N. Hartman, Richard Eldon, Peter E. Grebow, Colin Markland, Lixia Wang, Y. Nancy Wong
Publikováno v:
The Journal of Clinical Pharmacology. 38:971-978
An open-label, randomized, crossover study was performed in healthy male volunteers to evaluate the potential pharmacokinetic and pharmacodynamic interactions and tolerability of single oral doses of modafinil (200 mg) and dextroamphetamine (10 mg).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db5b3ac82c842bc4418503f11fc08b8
https://doi.org/10.1002/j.1552-4604.1998.tb04395.x
https://doi.org/10.1002/j.1552-4604.1998.tb04395.x
Publikováno v:
Journal of clinical pharmacology. 38(3)
Modafinil is a novel wake-promoting agent being developed for treatment of excessive daytime sleepiness associated with narcolepsy. An open, 3 x 3 Latin square, randomized, cross-over study was performed in healthy males to compare the pharmacokineti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef763e375e0e35e6ff13fd74727f77cd
https://pubmed.ncbi.nlm.nih.gov/9549666
https://pubmed.ncbi.nlm.nih.gov/9549666
Publikováno v:
Pharmacology, biochemistry, and behavior. 40(1)
The contribution of changes in rate of gastric emptying to the anorectic effect of (-)-threo-chlorocitric acid (chlorocitrate) was assessed by examining the effect of this drug in sham feeding rats, a preparation where gastric distention does not occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08c94cdf4a0160583f3ccb17ecf8c7c
https://pubmed.ncbi.nlm.nih.gov/1780349
https://pubmed.ncbi.nlm.nih.gov/1780349
Autor:
Watson B. Laughton
Publikováno v:
Behavioral and Brain Sciences. 13:308-309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13dca11e3e9dfb56b1254517bdb4c6df
https://doi.org/10.1017/s0140525x00078833
https://doi.org/10.1017/s0140525x00078833
Publikováno v:
Journal of the autonomic nervous system. 16(3)
The dynamics of gastric acid secretion induced by electrical stimulation of the cervical vagus in the anesthetized rat were investigated using a continuous collection-titration system permitting high temporal resolution. Stimulation with pulse rates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f004876465e51e12c7b39903ddb0c37b
https://pubmed.ncbi.nlm.nih.gov/3745775
https://pubmed.ncbi.nlm.nih.gov/3745775
Publikováno v:
Physiologybehavior. 35(6)
We investigated the utility of carcass water for predicting adiposity in a sample of 373 rats and mice from nine studies involving several models of obesity and experimental manipulations. A single regression equation was derived for estimating perce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f783e09d686688ec35216743548e6bc
https://pubmed.ncbi.nlm.nih.gov/4095182
https://pubmed.ncbi.nlm.nih.gov/4095182
Autor:
Wong, Y. Nancy, Simcoe, Donna, Hartman, Linda N., Laughton, Watson B., King, S. Peter, McCormick, George C., Grebow, Peter E.
Publikováno v:
Journal of Clinical Pharmacology; Jan1999, Vol. 39 Issue 1, p30-40, 11p