Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis

Autor: Samejima, Kumiko, Booth, Daniel G, Ogawa, Hiromi, Paulson, James R., Xie, Linfeng, Watson, Cara A, Platani, Melpomeni, Kanemaki, Masato T, Earnshaw, William C

Publikováno v: Samejima, K, Booth, D G, Ogawa, H, Paulson, J R, Xie, L, Watson, C A, Platani, M, Kanemaki, M T & Earnshaw, W C 2018, ' Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis ', Journal of Cell Science, vol. 131, no. 4 . https://doi.org/10.1242/jcs.210187

The requirement for condensin in chromosome formation in somatic cells remains unclear, as imperfectly condensed chromosomes do form in cells depleted of condensin by conventional methodologies. In order to dissect the roles of condensin at different

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https://www.pure.ed.ac.uk/ws/files/57171704/Functional_analysis_after_rapid_degradation_PUB_OA_CC_BY_jcs210187.full.pdf