Nutritional management of inherited copper-associated hepatitis in the Labrador retriever

Autor: Fieten, Hille, Biourge, Vincent C., Watson, Adrian L., Leegwater, Peter A.J., van den Ingh, Ted S.G.A.M., Rothuizen, Jan

Publikováno v: In The Veterinary Journal March 2014 199(3):429-433

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The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers

Autor: Fieten, Hille, Gill, Yadvinder, Martin, Alan J, Concilli, Mafalda, Dirksen, Karen, van Steenbeek, Frank G, Spee, Bart, van den Ingh, Ted S G A M, Martens, Ellen C C P, Festa, Paola, Chesi, Giancarlo, van de Sluis, Bart, Houwen, Roderick H J H, Watson, Adrian L, Aulchenko, Yurii S, Hodgkinson, Victoria L, Zhu, Sha, Petris, Michael J, Polishchuk, Roman S, Leegwater, Peter A J, Rothuizen, Jan, LS Interne geneeskunde, Spoedkliniek Gezelschapsdieren Midden-NL, Onderzoek, Universitair Veterinair Diagnostisch Lab, dCSCA RMSC-1, dCSCA AVR

Publikováno v: Disease Models & Mechanisms, 9(1), 25. Company of Biologists Ltd
Disease Models & Mechanisms
Disease Models & Mechanisms, 9, 25. Company of Biologists Ltd
Disease Models & Mechanisms, Vol 9, Iss 1, Pp 25-38 (2016)
Disease models & mechanisms, 9(1), 25-38. COMPANY OF BIOLOGISTS LTD

The deleterious effects of a disrupted copper metabolism are illustrated by hereditary diseases caused by mutations in the genes coding for the copper transporters ATP7A and ATP7B. Menkes disease, involving ATP7A, is a fatal neurodegenerative disorde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41d50870833b89d395c2eaa5fbc7f318
https://research.rug.nl/en/publications/e0cf5b7e-dca2-46bb-85e7-1aa57477db95

Gene expression patterns in the progression of canine copper-associated chronic hepatitis

Autor: Dirksen, Karen, Spee, Bart, Penning, Louis C, van den Ingh, Ted S G A M, Burgener, Iwan A, Watson, Adrian L, Groot Koerkamp, Marian, Rothuizen, Jan, van Steenbeek, Frank G, Fieten, Hille, dCSCA RMSC-1, dCSCA AVR

Publikováno v: PLoS ONE, Vol 12, Iss 5, p e0176826 (2017)
PLoS ONE
PLoS One, 12(5). Public Library of Science

Copper is an essential trace element, but can become toxic when present in abundance. The severe effects of copper-metabolism imbalance are illustrated by the inherited disorders Wilson disease and Menkes disease. The Labrador retriever dog breed is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c635ecb7320406f2648f613dbe9bb9
http://europepmc.org/articles/PMC5411060?pdf=render

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