Synthesis and Evaluation of ¹¹ C-Labeled Triazolones as Probes for Imaging Fatty Acid Synthase Expression by Positron Emission Tomography.

Autor: Kelly JM; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY 10065, USA.; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, New York, NY 10021, USA., Jeitner TM; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY 10065, USA., Waterhouse NN; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, New York, NY 10021, USA., Qu W; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, New York, NY 10021, USA., Linstad EJ; Departments of Medicinal Chemistry & Pharmacognosy and Chemistry, University of Illinois-Chicago, Chicago, IL 60612, USA.; Department of Chemistry, University of Nebraska-Lincoln, Lincoln, NE 68588, USA., Samani B; Departments of Medicinal Chemistry & Pharmacognosy and Chemistry, University of Illinois-Chicago, Chicago, IL 60612, USA., Williams C Jr; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY 10065, USA., Nikolopoulou A; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY 10065, USA.; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, New York, NY 10021, USA., Amor-Coarasa A; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY 10065, USA., DiMagno SG; Departments of Medicinal Chemistry & Pharmacognosy and Chemistry, University of Illinois-Chicago, Chicago, IL 60612, USA., Babich JW; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY 10065, USA.; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, New York, NY 10021, USA.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY 10065, USA.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Feb 25; Vol. 27 (5). Date of Electronic Publication: 2022 Feb 25.

Otto: a 4.04 GBq (109 mCi) ⁶⁸ Ge/ ⁶⁸ Ga generator, first of its kind - extended quality control and performance evaluation in the clinical production of [ ⁶⁸ Ga]Ga-PSMA-11.

Autor: Waterhouse NN; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, 516 E 72nd St, New York, NY, 10021, USA., Amor-Coarasa A; Radiochemistry Laboratory, Albert Einstein College of Medicine, Department of Radiology, Montefiore Medical Center, Bronx, NY, USA., Nikolopoulou A; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, 516 E 72nd St, New York, NY, 10021, USA.; Division of Radiopharmaceutical Sciences, Department of Radiology, Weill Cornell Medicine, Belfer Research Building, Room 1600, 413 E 69th St, New York, NY, 10021, USA., Babich JW; Citigroup Biomedical Imaging Center, Weill Cornell Medicine, 516 E 72nd St, New York, NY, 10021, USA. job2060@med.cornell.edu.; Division of Radiopharmaceutical Sciences, Department of Radiology, Weill Cornell Medicine, Belfer Research Building, Room 1600, 413 E 69th St, New York, NY, 10021, USA. job2060@med.cornell.edu.; Molecular Imaging Innovations Institute (MI3), Department of Radiology, Weill Cornell Medicine, New York, NY, USA. job2060@med.cornell.edu.; Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York, NY, USA. job2060@med.cornell.edu.

Publikováno v: EJNMMI radiopharmacy and chemistry [EJNMMI Radiopharm Chem] 2020 Feb 03; Vol. 5 (1), pp. 5. Date of Electronic Publication: 2020 Feb 03.

[1-¹¹C]-Butanol Positron Emission Tomography reveals an impaired brain to nasal turbinates pathway in aging amyloid positive subjects.

Autor: Mehta, Neel H.^1,2 (AUTHOR), Wang, Xiuyuan¹ (AUTHOR), Keil, Samantha A.¹ (AUTHOR), Xi, Ke¹ (AUTHOR), Zhou, Liangdong¹ (AUTHOR), Lee, Kevin^1,3 (AUTHOR), Tan, Wanbin¹ (AUTHOR), Spector, Edward^1,4 (AUTHOR), Goldan, Amirhossein^1,5 (AUTHOR), Kelly, James⁶ (AUTHOR), Karakatsanis, Nicolas A.⁵ (AUTHOR), Mozley, P. David^1,7 (AUTHOR), Nehmeh, Sadek⁵ (AUTHOR), Chazen, J. Levi⁸ (AUTHOR), Morin, Simon⁵ (AUTHOR), Babich, John⁹ (AUTHOR), Ivanidze, Jana^1,5 (AUTHOR), Pahlajani, Silky¹ (AUTHOR), Tanzi, Emily B.¹ (AUTHOR), Saint-Louis, Leslie¹⁰ (AUTHOR)

Publikováno v: Fluids & Barriers of the CNS. 4/2/2024, Vol. 21 Issue 1, p1-13. 13p.

Decreased CSF clearance and increased brain amyloid in Alzheimer's disease.

Autor: Li, Yi¹ (AUTHOR) yil4008@med.cornell.edu, Rusinek, Henry² (AUTHOR), Butler, Tracy¹ (AUTHOR), Glodzik, Lidia¹ (AUTHOR), Pirraglia, Elizabeth³ (AUTHOR), Babich, John¹ (AUTHOR), Mozley, P. David¹ (AUTHOR), Nehmeh, Sadek¹ (AUTHOR), Pahlajani, Silky¹ (AUTHOR), Wang, Xiuyuan¹ (AUTHOR), Tanzi, Emily B.¹ (AUTHOR), Zhou, Liangdong¹ (AUTHOR), Strauss, Sara¹ (AUTHOR), Carare, Roxana O.⁴ (AUTHOR), Theise, Neil⁵ (AUTHOR), Okamura, Nobuyuki⁶ (AUTHOR), de Leon, Mony J.¹ (AUTHOR) mdl4001@med.cornell.edu

Publikováno v: Fluids & Barriers of the CNS. 3/14/2022, Vol. 19 Issue 1, p1-9. 9p.