Mouse IgG2a Isotype Therapeutic Antibodies Elicit Superior Tumor Growth Control Compared with mIgG1 or mIgE

Autor: Vukovic, Natasa, Segués, Aina, Huang, Shuyu, Waterfall, Martin, Sijts, Alice J A M, Zaiss, Dietmar M, Immunologie

Publikováno v: Cancer research communications, 3(1), 109
Cancer Res Commun

In the last decades, antibody-based tumor therapy has fundamentally improved the efficacy of treatment for patients with cancer. Currently, almost all tumor antigen–targeting antibodies approved for clinical application are of IgG1 Fc isotype. Simi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8776ca999985d991073d854ea380e68f
https://dspace.library.uu.nl/handle/1874/427694

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Dielectrophoretic Characterisation of Mammalian Cells above 100 MHz

Autor: Chung Colin, Waterfall Martin, Pells Steve, Menachery Anoop, Smith Stewart, Pethig Ronald

Publikováno v: Journal of Electrical Bioimpedance, Vol 2, Iss 1, Pp 64-71 (2011)

Dielectrophoresis (DEP) is a label-free technique for the characterization and manipulation of biological particles - such as cells, bacteria and viruses. Many studies have focused on the DEP cross-over frequency fxo1, where cells in a non-uniform el

Externí odkaz: https://doaj.org/article/ec54500b6c2b4a579ddc97654f353845

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival

Autor: Watson, Rebecca L., Mcneilly, Tom N., Watt, Kathryn A., Pemberton, Josephine M., Pilkington, Jill G., Waterfall, Martin, Hopper, Phoebe R.t., Cooney, Daniel, Zamoyska, Rose, Nussey, Daniel H.

Publikováno v: Watson, R L, Mcneilly, T N, Watt, K A, Pemberton, J M, Pilkington, J G, Waterfall, M, Hopper, P R T, Cooney, D, Zamoyska, R & Nussey, D H 2016, ' Cellular and humoral immunity in a wild mammal: Variation with age & sex and association with overwinter survival ', Ecology and Evolution . https://doi.org/10.1002/ece3.2584

Immune defenses are expected to be crucial for survival under the considerable parasite pressures experienced by wild animals. However, our understanding of the association between immunity and fitness in nature remains limited due to both the comple

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::3c925ba3e8fc94dc4f7418be15eda6cd
https://www.pure.ed.ac.uk/ws/files/29125675/Watson_et_al_2016_Ecology_and_Evolution.pdf