Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Wataru eSugiura"'
Autor:
Masaaki eNakashima, Hirotaka eOde, Koji eSuzuki, Masayuki eFujino, Masami eMaejima, Yuki eKimura, Takashi eMasaoka, Junko eHattori, Masakazu eMatsuda, Atsuko eHachiya, Yoshiyuki eYokomaku, Atsuo eSuzuki, Nobuhisa eWatanabe, Wataru eSugiura, Yasumasa eIwatani
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Darunavir (DRV) is one of the most powerful protease inhibitors for treating human immunodeficiency virus type-1 (HIV-1) infection and presents a high genetic barrier to the generation of resistant viruses. However, DRV-resistant HIV-1 infrequently e
Externí odkaz:
https://doaj.org/article/7740db355974464384f8d112d569491d
Autor:
Hirotaka eOde, Masakazu eMatsuda, Kazuhiro eMatsuoka, Atsuko eHachiya, Junko eHattori, Yumiko eKito, Yoshiyuki eYokomaku, Yasumasa eIwatani, Wataru eSugiura
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Human immunodeficiency virus type-1 (HIV-1) exhibits high between-host genetic diversity and within-host heterogeneity, recognized as quasispecies. Because HIV-1 quasispecies fluctuate in terms of multiple factors, such as antiretroviral exposure and
Externí odkaz:
https://doaj.org/article/c76f72ca11a8448ba38711f004696bcd
Autor:
Satoko eMatsunaga, Takashi eMasaoka, Tatsuya eSawasaki, Ryo eMorishita, Yasumasa eIwatani, Masashi eTatsumi, Naoki eYamamoto, Yaeta eEndo, Wataru eSugiura, Akihide eRyo
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Due to their high frequency of genomic mutations, human retroviruses often develop resistance to antiretroviral drugs. The emergence of drug-resistant human immunodeficiency virus type 1 (HIV-1) is a significant obstacle to the effective long-term tr
Externí odkaz:
https://doaj.org/article/81cb427c5a314d53ae42867413d84caa
Publikováno v:
Frontiers in Microbiology, Vol 3 (2012)
Virus replication in the host proceeds by chains of interactions between viral and host proteins. The interactions are deeply influenced by host immune molecules and anti-viral compounds, as well as by mutations in viral proteins. To understand how t
Externí odkaz:
https://doaj.org/article/a31cd471363945ac9b73502d7b9779fd