Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Wataru Nunomura"'
Autor:
Wataru Nunomura, Kenichi Sawada
Publikováno v:
Haematologica, Vol 97, Iss 10 (2012)
Externí odkaz:
https://doaj.org/article/cd85c49002564328985f8a0733147a93
Publikováno v:
International Journal of Cell Biology, Vol 2011 (2011)
Membrane skeletal protein 4.1R is the prototypical member of a family of four highly paralogous proteins that include 4.1G, 4.1N, and 4.1B. Two isoforms of 4.1R (4.1R135 and 4.1R80), as well as 4.1G, are expressed in erythroblasts during terminal dif
Externí odkaz:
https://doaj.org/article/af1d7aaf17df4db3a7eb5f46906811b4
Autor:
Kumi Ubukawa, Isuzu Kobayashi, Hideki Mochizuki, Wataru Nunomura, Kotomi Sugawara, Naoto Takahashi, Hideki Wakui, Eri H. Hayakawa, Katsuya Araki, Kenichi Sawada
Publikováno v:
International Journal of Hematology. 108:130-138
Although the neuronal protein α-synuclein (α-syn) is thought to play a central role in the pathogenesis of Parkinson's disease (PD), its physiological function remains unknown. It is known that α-syn is also abundantly expressed in erythrocytes. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee0fb553ddb4b28c2f8e7add6b57969
https://doi.org/10.1007/s12185-018-2457-8
https://doi.org/10.1007/s12185-018-2457-8
Autor:
Hideki Wakui, Mika Yonezawa, Tatsufumi Goto, Mizuki Nakagawa, Kotomi Sugawara, Wataru Nunomura, Shigeyoshi Nakamura, Shun-ichi Kidokoro
Publikováno v:
Journal of Biochemistry. 160:299-308
It is widely believed that enzymatic activities in ectothermic organisms adapt to environmental temperatures. However, to date, no study has thoroughly compared multiple thermodynamic enzymatic characteristics across species living in dramatically di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b3f48580665b5da1348e94823d7be2
https://doi.org/10.1093/jb/mvw039
https://doi.org/10.1093/jb/mvw039
Publikováno v:
Biochemical and Biophysical Research Communications. 473:999-1004
Hydroxychloroquine (HCQ) is a widely used drug in the treatment of autoimmune diseases, such as arthritis and systemic lupus erythematosus. It has also been prescribed for the treatment of malaria owing to its lower toxicity compared to its closely r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc626479e148273c9562aa28a4c202e2
https://doi.org/10.1016/j.bbrc.2016.04.005
https://doi.org/10.1016/j.bbrc.2016.04.005
Autor:
Mika Yonezawa, Wataru Nunomura, Shun-ichi Kidokoro, Hideki Wakui, Kotomi Sugawara, Mizuki Nakagawa, Shigeyoshi Nakamura
Publikováno v:
Fisheries Science. 82:519-527
Vertebrates have three genes (LDHA, LDHB, and LDHC) encoding skeletal muscle-, heart muscle- and testis-specific lactate dehydrogenase (LDH, E.C. 1.1.1.27), respectively. The muscle and heart LDHs are tetramers formed by polypeptides encoded by LDHA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac82f2dde2bbafe9a1a31c19d121c04f
https://doi.org/10.1007/s12562-016-0972-1
https://doi.org/10.1007/s12562-016-0972-1
Autor:
Wataru Nunomura, Hideki Wakui, Tatsufumi Goto, Kenichi Sawada, Kumi Ubukawa, Naoto Takahashi, Isuzu Kobayashi, Yong-Mei Guo, Ken Asanuma, Yumi Sasaki, Kotomi Sugawara
Publikováno v:
Experimental Hematology. 72:14-26.e1
More than 2million human erythroblasts extrude their nuclei every second in bone marrow under hypoxic conditions (7% O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3240a45944933b54b7bee0f49b512e
https://doi.org/10.1016/j.exphem.2019.02.004
https://doi.org/10.1016/j.exphem.2019.02.004
Autor:
Yuichi Takakuwa, Noriyoshi Isozumi, Wataru Nunomura, Hideki Wakui, Shinya Ohki, Yuji Jinbo, Shun-ichi Kidokoro, Shigeyoshi Nakamura
Publikováno v:
Cell Biochemistry and Biophysics. 69:7-19
Calmodulin (CaM) binds to the FERM domain of 80 kDa erythrocyte protein 4.1R (R30) independently of Ca(2+) but, paradoxically, regulates R30 binding to transmembrane proteins in a Ca(2+)-dependent manner. We have previously mapped a Ca(2+)-independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa199099421fe7780af89b11c0fee41
https://doi.org/10.1007/s12013-013-9758-6
https://doi.org/10.1007/s12013-013-9758-6
Autor:
Hideki Wakui, Wataru Nunomura, Tatsufumi Goto, Shigeyoshi Nakamura, Kotomi Sugawara, Shun-ichi Kidokoro
Publikováno v:
Biochemical and biophysical research communications. 479(4)
Lactate dehydrogenase (LDH) is a glycolytic enzyme that catalyzes the final step of glycolysis and produces NAD+. In somatic cells, LDH forms homotetramers and heterotetramers that are encoded by two different genes: LDHA (skeletal muscle type, M) an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8417fc2bf0c32e2c37cdd713e5df8213
https://pubmed.ncbi.nlm.nih.gov/27671200
https://pubmed.ncbi.nlm.nih.gov/27671200
Autor:
Wataru, Nunomura
Publikováno v:
[Rinsho ketsueki] The Japanese journal of clinical hematology. 57(7)
Two key questions remain unanswered in the erythropoiesis field: Why and how do erythroblasts enucleate in mammalian species? Recent studies have unveiled the roles of various molecules, cytoskeletal proteins, motor proteins, vesicle transport, signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::392eb9d7fbc2c8309bfd060bd3111986
https://pubmed.ncbi.nlm.nih.gov/27498741
https://pubmed.ncbi.nlm.nih.gov/27498741