Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Wataru Nemoto"'
Autor:
Shiori Iwane, Wataru Nemoto, Tomoyoshi Miyamoto, Tomonori Hayashi, Masayuki Tanaka, Kazuki Uchitani, Tatsuya Muranaka, Masanori Fujitani, Yuichi Koizumi, Atsushi Hirata, Maho Tsubota, Fumiko Sekiguchi, Koichi Tan-No, Atsufumi Kawabata
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Given possible involvement of the central and peripheral angiotensin system in pain processing, we conducted clinical and preclinical studies to test whether pharmacological inhibition of the angiotensin system would prevent diabetic periphe
Externí odkaz:
https://doaj.org/article/870869dc706643ddbf7385bad4356947
Autor:
Osamu Nakagawasai, Kohei Takahashi, Taisei Koyama, Ryota Yamagata, Wataru Nemoto, Koichi Tan-No
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-9 (2023)
Abstract Angiotensin (Ang)-converting-enzyme (ACE) 2 converts Ang II into Ang (1–7), which in turn acts on MAS receptors (ACE2/Ang (1–7)/MAS receptors pathway). This pathway has neuroprotective properties, making it a potential therapeutic target
Externí odkaz:
https://doaj.org/article/3645107860874d7e8f14def8e8f78694
Autor:
Osamu Nakagawasai, Kohei Takahashi, Wakana Sakuma, Wataru Nemoto, Ruka Kobayashi, Tomohiro Hoshi, Satoshi Matsumoto, Takeshi Tadano, Koichi Tan-No
Publikováno v:
Journal of Pharmacological Sciences, Vol 152, Iss 1, Pp 61-67 (2023)
Fatigue is a serious health problem, and long-term fatigue can lead to mental illnesses and accelerated aging. Oxidative stress, which causes excessive production of reactive oxygen species, is generally thought to increase during exercise and is an
Externí odkaz:
https://doaj.org/article/2a8aca1541834ab7b4f1d4793dc10ba6
Publikováno v:
Journal of Pharmacological Sciences, Vol 148, Iss 3, Pp 326-330 (2022)
Extracellular signal-regulated protein kinase 5 (ERK5) has various physiological functions. However, the physiological role of ERK5 in the treatment of mice with an illicit drug such as methamphetamine (METH) remains unknown. We revealed that mice tr
Externí odkaz:
https://doaj.org/article/3099fbb27edb464e8dda141d2556737a
Publikováno v:
Biology, Vol 12, Iss 5, p 755 (2023)
Angiotensin (Ang)-generating system has been confirmed to play an important role in the regulation of fluid balance and blood pressure and is essential for the maintenance of biological functions. Ang-related peptides and their receptors are found th
Externí odkaz:
https://doaj.org/article/1c2ef550047d4c46b0927ed5cf724f3e
Autor:
Wataru Nemoto, Yoshihiro Yamanishi, Vachiranee Limviphuvadh, Shunsuke Fujishiro, Sakie Shimamura, Aoi Fukushima, Hiroyuki Toh
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/5d37a77931874d03b3b52e355a4d4d5d
Autor:
Wataru Nemoto, Yoshihiro Yamanishi, Vachiranee Limviphuvadh, Shunsuke Fujishiro, Sakie Shimamura, Aoi Fukushima, Hiroyuki Toh
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
The GGIP web server (https://protein.b.dendai.ac.jp/GGIP/) provides a web application for GPCR-GPCR interaction pair prediction by a support vector machine. The server accepts two sequences in the FASTA format. It responds with a prediction that the
Externí odkaz:
https://doaj.org/article/9cda99ae7acb45aabf219f9ba5387fac
Autor:
Osamu Nakagawasai, Kotaro Yamada, Takayo Odaira, Kohei Takahashi, Wataru Nemoto, Wakana Sakuma, Miharu Wakou, Jia-Rong Lin, Koichi Tan-No
Publikováno v:
Journal of Pharmacological Sciences, Vol 143, Iss 1, Pp 52-55 (2020)
Recently, we has reported that AMPK activator has antidepressant effect. Previous our study suggested that liver hydrolysate (LH) activated adenosine monophosphate-activated protein kinase (AMPK) in periphery. However, the effect of LH on depression
Externí odkaz:
https://doaj.org/article/cd1380a0456345859d82a7aae389c455
Autor:
Kohei Takahashi, Osamu Nakagawasai, Wataru Nemoto, Takayo Odaira, Wakana Sakuma, Hiroshi Onogi, Hiroaki Nishijima, Ryuji Furihata, Yukio Nemoto, Hiroyuki Iwasa, Koichi Tan-No, Takeshi Tadano
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Patients with inflammatory bowel disease (IBD), including those with ulcerative colitis and Crohn’s disease, have higher rates of psychiatric disorders, such as depression and anxiety; however, the mechanism of psychiatric disor
Externí odkaz:
https://doaj.org/article/fcc176da7b434786ac4fb7c6a883f715
Autor:
Osamu Nakagawasai, Kotaro Yamada, Wakana Sakuma, Kohei Takahashi, Takayo Odaira, Ryota Yamagata, Wataru Nemoto, Akika Ejima, Kenji Sato, Koichi Tan-No
Publikováno v:
Journal of Functional Foods, Vol 76, Iss , Pp 104312- (2021)
The present study was conducted to identify anti-fatigue peptides in porcine liver hydrolysate (LH) and to evaluate their effects. Peptides in LH were fractionated into hydrophilic and hydrophobic fractions and further into peptides with amino groups
Externí odkaz:
https://doaj.org/article/e402c29dba244182aec730774da6df25