Výsledky vyhledávání - "Wataru Jinnai"

Intravenous Edaravone plus Therapeutic Hypothermia Offers Limited Neuroprotection in the Hypoxic-Ischaemic Newborn Piglet

Autor: Makoto Nakamura, Wataru Jinnai, Takayuki Wakabayashi, Aya Morimoto, Takashi Kusaka, Takashi Iwase, Masaki Ueno, Masashiro Sugino, Satoshi Yamato, Tsutomu Mitsuie, Yinmon Htun, Takanori Miki, Yasuhiro Nakao, Kosuke Koyano, Shinji Nakamura, Saneyuki Yasuda, Sonoko Ijichi Kondo

Publikováno v: Neonatology. 117(6)

Background: Therapeutic hypothermia (TH) is a standard therapy for neonatal hypoxic-ischaemic encephalopathy. One potential additional therapy is the free radical scavenger edaravone (EV; 3-methyl-1-phenyl-2-pyrazolin-5-one). Objectives and Methods:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a776b714aa3bad1b37d26e6662993f5
https://pubmed.ncbi.nlm.nih.gov/33113527

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Relationship between prolonged neural suppression and cerebral hemodynamic dysfunction during hypothermia in asphyxiated piglets

Autor: Shinji Nakamura, Saneyuki Yasuda, Yinmon Htun, Takashi Kusaka, Takanori Miki, Kosuke Koyano, Wataru Jinnai, Masaki Ueno, Takayuki Wakabayashi, Takashi Iwase, Yasuhiro Nakao, Makoto Nakamura, Satoshi Yamato

Publikováno v: Brain and Development. 40:649-661

Hypothermia (HT) improves the outcome of neonatal hypoxic-ischemic encephalopathy. Here, we investigated changes during HT in cortical electrical activity using amplitude-integrated electroencephalography (aEEG) and in cerebral blood volume (CBV) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed5cbc46abfdd6177c7807f244a04a1a
https://doi.org/10.1016/j.braindev.2018.04.010

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Green light-emitting diode phototherapy for neonatal hyperbilirubinemia: Randomized controlled trial

Autor: Takashi Kusaka, Takaaki Sadamura, Toru Kuboi, Hitoshi Okada, Kohichiroh Nii, Megumi Takahashi, Akiko Nakano, Satoshi Yamato, Wataru Jinnai, Makoto Arioka, Susumu Itoh

Publikováno v: Pediatrics international : official journal of the Japan Pediatric Society. 61(5)

BACKGROUND The main photochemical pathway in phototherapy for neonatal hyperbilirubinemia is the production and elimination (in bile or urine) of cyclobilirubin, which is a structural photoisomer of bilirubin, and which is most efficiently produced b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850129cc00993986832cfd7b57c83aef
https://pubmed.ncbi.nlm.nih.gov/30838731

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Simultaneous measurement of cerebral hemoglobin oxygen saturation and blood volume in asphyxiated neonates by near-infrared time-resolved spectroscopy

Autor: Toru Kuboi, Wataru Jinnai, Takashi Kusaka, Yukihiko Konishi, Kosuke Koyano, Kenji Kanenishi, Satoshi Hamano, Shinji Nakamura, Tomoko Nishida, Saneyuki Yasuda

Publikováno v: Brain and Development. 37:925-932

Background Hypoxic-ischemic encephalopathy (HIE) usually results in a poor clinical outcome even when treated with hypothermic therapy (HT). Early postnatal changes in cerebral blood oxygenation and hemodynamics may be critical determinants of brain

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6defe6fe2de9051a9f5a52d20355d6
https://doi.org/10.1016/j.braindev.2015.04.002

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Surgery for gastroesophageal reflux disease with Gaucher disease type 2

Autor: Takeo Kondo, Ryuichi Shimono, Sonoko Kondo, Aya Tanaka, Saneyuki Yasuda, Hiroyuki Kubo, Takayuki Fujii, Wataru Jinnai, Takashi Kusaka, Kosuke Koyano

Publikováno v: Pediatrics International. 58:610-612

Gaucher disease, the most common lysosomal storage disease, is sometimes complicated with gastroesophageal reflux disease (GERD). The present patient was a 136-day-old Japanese boy with Gaucher disease type 2. Enzyme replacement therapy and chemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f2e66d77758975dc65b8234abd22807
https://doi.org/10.1111/ped.12851

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Relationship between early changes in cerebral blood volume and electrocortical activity after hypoxic–ischemic insult in newborn piglets

Autor: Susumu Itoh, Takashi Kusaka, Shinji Nakamura, Saneyuki Yasuda, Hitoshi Okada, Kosuke Koyano, Kenichi Isobe, Makoto Nakamura, Wataru Jinnai, Takanori Miki, Masaki Ueno

Publikováno v: Brain and Development. 36:563-571

Early changes in cerebral hemodynamics and depressed electrocortical activity have been reported after a hypoxic-ischemic (HI) insult. However, the relationship between these two parameters is unclear. This study aimed to examine the relationship bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc0efa441eea5342d76aa71c416f92e
https://doi.org/10.1016/j.braindev.2013.08.005

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Hydrogen ventilation combined with mild hypothermia improves short-term neurological outcomes in a 5-day neonatal hypoxia-ischaemia piglet model

Autor: Shinji Nakamura, Aya Morimoto, Takayuki Wakabayashi, Ken-ichi Ohta, Yasuhiro Nakao, Takanori Miki, Makoto Nakamura, Sonoko Kondo, Masaki Ueno, Saneyuki Yasuda, Tsutomu Mitsuie, Takashi Kusaka, Kosuke Koyano, Wataru Jinnai, Yinmon Htun, Kazumichi Fujioka, Masashiro Sugino, Ikuko Kato, Satoshi Yamato

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports

Despite its poor outcomes, therapeutic hypothermia (TH) is the current standard treatment for neonatal hypoxic-ischaemic encephalopathy (HIE). In this study, due to its antioxidant, anti-inflammatory, and antiapoptotic properties, the effectiveness o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::663111712a05f45a2b80007123b04354
https://hdl.handle.net/20.500.14094/90005766

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Hypoxic-Ischemic Encephalopathy-Associated Liver Fatty Degeneration and the Effects of Therapeutic Hypothermia in Newborn Piglets

Autor: Takanori Miki, Shinji Nakamura, Makoto Nakamura, Takashi Kusaka, Masaki Ueno, Hiroyuki Kubo, Takayuki Fujii, Aya Tanaka, Yoichi Chiba, Kenji Kanenishi, Satoshi Yamato, Wataru Jinnai, Ryuichi Shimono, Kosuke Koyano, Saneyuki Yasuda

Publikováno v: Neonatology. 111(3)

Background: Although liver can be injured under the hypoxic-ischemic encephalopathy (HIE) condition, there is currently no histopathological evidence. Therapeutic hypothermia is used to protect the brain; however, the therapeutic potential for concom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb8250676e08f853d8b0fab7e4fef94
https://pubmed.ncbi.nlm.nih.gov/27842320

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