Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Wataru Aizu"'
Autor:
Kishore Guda, Tong Xin, Michael S. Thibodeau, Wataru Aizu, Charles Giardina, Prashant R. Nambiar, Daniel W. Rosenberg
Publikováno v:
Toxicology Letters. 144:213-224
We examined the p53 response following acute exposure of mice to the colon-specific carcinogen azoxymethane (AOM). No overall induction of p53-regulated genes was observed in the mouse colon, and only a small subpopulation of apoptotic colonocytes sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088fa72434cc55d19519a97ef7cb119c
https://doi.org/10.1016/s0378-4274(03)00221-2
https://doi.org/10.1016/s0378-4274(03)00221-2
Autor:
Wataru Aizu, Weiwei Gao, Omid C. Farokhzad, Farhan Murshed, Pooja Ghatalia, Carolina Salvador-Morales, Robert Langer
Publikováno v:
Expert review of anticancer therapy. 9(2)
Multifunctional nanoparticles promise significantly better treatment for prostate cancer. This review begins with a molecular and physiological overview of prostate cancer, including current treatments in various stages of disease development. Emergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ff5d83dbee050d41546b6b6e5164df
https://pubmed.ncbi.nlm.nih.gov/19192959
https://pubmed.ncbi.nlm.nih.gov/19192959
Autor:
Daniel W. Rosenberg, Colleen C. Boes, Cassandra A. Godman, Emily J. Noonan, Glenn S. Belinsky, Bindi M. Doshi, Charles Giardina, Christopher Flynn, Wataru Aizu, Prashant R. Nambiar
Publikováno v:
Biochemical pharmacology. 72(8)
The p53 tumor suppressor protein is sequence-normal in azoxymethane (AOM)-induced mouse colon tumors, making them a good model for human colon cancers that retain a wild type p53 gene. Cellular localization and co-immunoprecipitation experiments usin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cbea6cb4f1c1a7786faa1a638ff9f4
https://pubmed.ncbi.nlm.nih.gov/16949053
https://pubmed.ncbi.nlm.nih.gov/16949053
Autor:
Prashant R, Nambiar, Charles, Giardina, Kishore, Guda, Wataru, Aizu, Rajiv, Raja, Daniel W, Rosenberg
Publikováno v:
Cancer research. 62(13)
Considering the importance of the oncogene checkpoint function of the alternating reading frame(ARF)-p53 pathway, studies were undertaken to evaluate the status of this pathway in azoxymethane (AOM)-induced mouse colon tumors. A PCR-based analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b36b9d1e6d5618a64f5dde4e3ecf6712
https://pubmed.ncbi.nlm.nih.gov/12097273
https://pubmed.ncbi.nlm.nih.gov/12097273
Publikováno v:
Cancer Research. 71:367-367
There has been a substantial interest in the development of targeted nanoparticles (NPs) that provide increased efficacy and lower toxicity for cancer therapy. One of the major obstacles has been the paucity of optimal targeting ligands that can disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bec346ddb5ec0bc565fcc57e591eefa4
https://doi.org/10.1158/1538-7445.am2011-367
https://doi.org/10.1158/1538-7445.am2011-367