Zobrazeno 1 - 10
of 794
pro vyhledávání: '"Wataru, Sakamoto"'
Autor:
Ryo Kanoda, Shotaro Nakajima, Satoshi Fukai, Motonobu Saito, Katsuharu Saito, Hiroya Suzuki, Tomohiro Kikuchi, Azuma Nirei, Hirokazu Okayama, Kosaku Mimura, Hiroyuki Hanayama, Wataru Sakamoto, Tomoyuki Momma, Zenichiro Saze, Koji Kono
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Mismatch repair deficient (dMMR)/microsatellite instability-high (MSI-H) gastric cancer (GC) exhibits an immune-active tumor microenvironment (TME) compared to MMR proficient (pMMR)/microsatellite stable/Epstein-Barr virus-negative [EBV (−
Externí odkaz:
https://doaj.org/article/57decaa1a5db4788a29f6759405f3d95
Autor:
Akira Matsuishi, Shotaro Nakajima, Motonobu Saito, Katsuharu Saito, Satoshi Fukai, Hideaki Tsumuraya, Ryo Kanoda, Tomohiro Kikuchi, Azuma Nirei, Akinao Kaneta, Hirokazu Okayama, Kosaku Mimura, Hiroyuki Hanayama, Wataru Sakamoto, Tomoyuki Momma, Zenichiro Saze, Koji Kono
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Activating antibody-dependent cellular cytotoxicity (ADCC) by targeting claudin-18 isoform 2 (CLDN18.2) using zolbetuximab, a monoclonal antibody against CLDN18.2, has been considered a promising novel therapeutic strategy for gastric cancer
Externí odkaz:
https://doaj.org/article/e8b0b52e782c4628902216379a95458f
Autor:
Akimichi Morita, Yukari Okubo, Shinichi Imafuku, Yayoi Tada, Keiichi Yamanaka, Kazumitsu Sugiura, Yukie Yamaguchi, Masahito Yasuda, Hitoshi Tsuchihashi, Morihisa Saitoh, Wataru Sakamoto, Ryuhei Okuyama, the study investigators
Publikováno v:
JEADV Clinical Practice, Vol 2, Iss 2, Pp 261-272 (2023)
Abstract Background Generalized pustular psoriasis (GPP) is a rare and often refractory disease, and GPP flares can be life threatening. The rarity of GPP prevents the development and evaluation of effective GPP‐specific treatments and obstructs di
Externí odkaz:
https://doaj.org/article/318927d3bab444da8a4fed58d243b566
Autor:
Cyprian Osinde, Wataru Sakamoto, Hiromi Kajiya-Kanegae, Islam S. Sobhy, Arthur K. Tugume, Anthony M. Nsubuga, Ivan Galis
Publikováno v:
Journal of Plant Interactions, Vol 18, Iss 1 (2023)
ABSTRACTSorghum (Sorghum bicolor (L.) Moench) is an important crop originated in Africa that shows susceptibility to herbivores. In this study, we identified two sorghum genotypes with highly contrasting levels of stem damage caused by the caterpilla
Externí odkaz:
https://doaj.org/article/71fde2286c7d4937bb2aac2b1fcc85bd
Autor:
Yusuke Kato, Hiroshi Kuroda, Shin-Ichiro Ozawa, Keisuke Saito, Vivek Dogra, Martin Scholz, Guoxian Zhang, Catherine de Vitry, Hiroshi Ishikita, Chanhong Kim, Michael Hippler, Yuichiro Takahashi, Wataru Sakamoto
Publikováno v:
eLife, Vol 12 (2023)
Photosynthesis is one of the most important reactions for sustaining our environment. Photosystem II (PSII) is the initial site of photosynthetic electron transfer by water oxidation. Light in excess, however, causes the simultaneous production of re
Externí odkaz:
https://doaj.org/article/c010d2a653f6485787a4429fdfd30f61
Autor:
Takuro Matsumoto, Shinji Ohki, Akinao Kaneta, Akira Matsuishi, Yuya Maruyama, Leo Yamada, Takeshi Tada, Hiroyuki Hanayama, Yohei Watanabe, Suguru Hayase, Hirokazu Okayama, Wataru Sakamoto, Tomoyuki Momma, Zenichiro Saze, Koji Kono
Publikováno v:
BMC Surgery, Vol 23, Iss 1, Pp 1-8 (2023)
Abstract Background Systemic inflammation has been reported to be associated with cancer progression and metastasis. Systemic inflammation score (SIS), calculated from preoperative serum albumin level and lymphocyte-to-monocyte ratio, has been shown
Externí odkaz:
https://doaj.org/article/92ff9b79e0c4422ebe679887a140053a
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
Photosynthetic electron transfer and its regulation processes take place on thylakoid membranes, and the thylakoid of vascular plants exhibits particularly intricate structure consisting of stacked grana and flat stroma lamellae. It is known that sev
Externí odkaz:
https://doaj.org/article/9a2b82085ae8413abe28bf202d0cdaf7
Autor:
Yuki Ohya, Yuri Ogiso, Masaya Matsuda, Harumi Sakae, Kentaro Nishida, Yasuhiro Miki, Todd E. Fox, Mark Kester, Wataru Sakamoto, Takeshi Nabe, Kazuyuki Kitatani
Publikováno v:
Cells, Vol 13, Iss 5, p 405 (2024)
Regulated necrosis, termed necroptosis, represents a potential therapeutic target for refractory cancer. Ceramide nanoliposomes (CNLs), considered potential chemotherapeutic agents, induce necroptosis by targeting the activating protein mixed lineage
Externí odkaz:
https://doaj.org/article/25245639c9bc45fd9cd5ba12f6ade3db
Publikováno v:
Plants, Vol 13, Iss 5, p 606 (2024)
Researchers have described protection mechanisms against the photoinhibition of photosystems under strong-light stress. Cyclic Electron Flow (CEF) mitigates electron acceptor-side limitation, and thus contributes to Photosystem I (PSI) protection. Ch
Externí odkaz:
https://doaj.org/article/ade1ffa285d7489e9065d216bbdd79ef
Autor:
Uwe Platzbecker, Joerg Chromik, Jan Krönke, Hiroshi Handa, Stephen Strickland, Yasushi Miyazaki, Martin Wermke, Wataru Sakamoto, Yoshifumi Tachibana, Tillmann Taube, Ulrich Germing
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background This report summarizes three phase I studies evaluating volasertib, a polo-like kinase inhibitor, plus azacitidine in adults with myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia, or acute myeloid leukemia. Methods
Externí odkaz:
https://doaj.org/article/f154eb6140c84e199690ca1fd5d13890