Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Wataru, Kurata"'
Autor:
Tsuyoshi Hayashi, Fumiko Shimizu, Yasuyuki Tashiro, Wataru Kurata, Yoshiro Niitsu, Takehiro Kukitsu, Irving Listowsky, Kunihiro Takanashi, Rai Shimoyama, Yasushi Sato, Naoki Fujitani, Naoko Kubo-Birukawa
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 117(32):19435-19445
The Ras/RAF/MEK/ERK pathway is an essential signaling cascade for various refractory cancers, such as those with mutant KRAS (mKRAS) and BRAF (mBRAF). However, there are unsolved ambiguities underlying mechanisms for this growth signaling thereby cre
Autor:
Yoshiro Niitsu, Rai Shimoyama, Akihiro Yoneda, Miyuki Nishimura, Fumiko Shimizu, Wataru Kurata, Yasuyuki Tashiro, Yasushi Sato
Publikováno v:
Journal of gastroenterology and hepatologyReferences. 36(12)
Background and aim In chronic hepatic diseases where treatment strategies are not available, deposited fibrotic tissues deteriorate the intrinsic regeneration capacity of the liver by creating special restrictions. Thus, if the anti-fibrosis modality
Autor:
Yoshiro, Niitsu, Yasushi, Sato, Kunihiro, Takanashi, Tsuyoshi, Hayashi, Naoko, Kubo-Birukawa, Fumiko, Shimizu, Naoki, Fujitani, Rai, Shimoyama, Takehiro, Kukitsu, Wataru, Kurata, Yasuyuki, Tashiro, Irving, Listowsky
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance A strategy to overcome therapeutic obstacles of mKRAS and mBRAF cancers is devised based on the finding, here, that the RAF/MEK/ERK cascade is by-passed by an autocrine signal loop established by interaction of CRAF with GSTP1. The inter
Publikováno v:
TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES. 61:268-273