Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Watal M Iwasaki"'
Autor:
Jeffrey A Fawcett, Fumio Sato, Takahiro Sakamoto, Watal M Iwasaki, Teruaki Tozaki, Hideki Innan
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0218407 (2019)
The domestication process of plants and animals typically involves intense inbreeding and directional selection for various traits. Here, we genotyped 370 Japanese Thoroughbred horses using the recently developed 670k SNP array and performed various
Externí odkaz:
https://doaj.org/article/41da38480a074175b3423e55346bc168
Autor:
Watal M Iwasaki, Hideki Innan
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184229 (2017)
As cancer cell populations evolve, they accumulate a number of somatic mutations, resulting in heterogeneous subclones in the final tumor. Understanding the mechanisms that produce intratumor heterogeneity is important for selecting the best treatmen
Externí odkaz:
https://doaj.org/article/cb22c3b81d4e47a29b999854ab41192c
Autor:
Atsushi Niida, Watal M. Iwasaki
Before the development of the next-generation sequencing (NGS) technology, carcinogenesis was regarded as a linear evolutionary process, driven by repeated acquisition of multiple driver mutations and Darwinian selection. However, recent cancer genom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf8ba190bc13fb00a1e55d1ab220b31
https://doi.org/10.5772/intechopen.100140
https://doi.org/10.5772/intechopen.100140
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc680cad1390e6b78de6cf1813d5a44
https://doi.org/10.2139/ssrn.4179404
https://doi.org/10.2139/ssrn.4179404
Publikováno v:
Molecular Biology and Evolution. 37:355-364
In order to understand how DNA sequences of transposable elements (TEs) evolve, extensive simulations were carried out. We first used our previous model, in which the copy number of TEs is mainly controlled by selection against ectopic recombination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5724373867da9997973435fcc41ccb40
https://doi.org/10.1093/molbev/msz220
https://doi.org/10.1093/molbev/msz220
Publikováno v:
Molecular Biology and Evolution. 35:1316-1321
Kimura's neutral theory provides the whole theoretical basis of the behavior of mutations in a Wright-Fisher population. We here discuss how it can be applied to a cancer cell population, in which there is an increasing interest in genetic variation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d14891b11eaf4134f835e091d4fc8eb
https://doi.org/10.1093/molbev/msy091
https://doi.org/10.1093/molbev/msy091
Autor:
Watal M. Iwasaki, Koichi Sato, Masato Taoka, Kazuki Takahashi, Toshiaki Isobe, Kunihiro Ohta, Masamichi Ishiai, Arisa Oda, Ryo Sakasai, Hidehiko Kawai, Yusuke Okamoto, Minoru Takata, Hideki Innan, Hitoshi Kurumizaka, Takashi Yamamoto, Masato T. Kanemaki, Kazuto Kugou, Akifumi Takaori-Kondo, Wataru Kobayashi
Publikováno v:
Nucleic Acids Research
During mild replication stress provoked by low dose aphidicolin (APH) treatment, the key Fanconi anemia protein FANCD2 accumulates on common fragile sites, observed as sister foci, and protects genome stability. To gain further insights into FANCD2 f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a337d2035b2efa36fbaa239c5257159d
https://doi.org/10.1093/nar/gky058
https://doi.org/10.1093/nar/gky058
Autor:
Watal M. Iwasaki, Fumio Sato, Jeffrey A. Fawcett, Hideki Innan, Teruaki Tozaki, Takahiro Sakamoto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0218407 (2019)
PLoS ONE, Vol 14, Iss 7, p e0218407 (2019)
The domestication process of plants and animals typically involves intense inbreeding and directional selection for various traits. Here, we genotyped 370 Japanese Thoroughbred horses using the recently developed 670k SNP array and performed various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0712c4cb692b15438fd0c9081f30b63f
http://europepmc.org/articles/PMC6655603
http://europepmc.org/articles/PMC6655603
Autor:
Masakado Kawata, Hajime Wakasa, Koji Tamura, Hitoshi Yokoyama, Lázaro M. Echenique-Díaz, Namiko Kamiyama, Antonio Cádiz, Watal M. Iwasaki, Yuki Nishimura
Publikováno v:
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution. 324:410-423
The divergent evolution of niche-related traits can facilitate adaptive radiation, yet identification of the genetic or molecular mechanisms underlying such trait changes remains a major challenge in evolutionary biology. Conducting a detailed morpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b68ab0d6929f0866e55f0fd2e6af83a
https://doi.org/10.1002/jez.b.22627
https://doi.org/10.1002/jez.b.22627
Autor:
Keiko Nakayama, Ryo Funayama, Hideaki Mori, Satoshi Tamate, Brian J. Camposano, Kenneth L. Krysko, Masakado Kawata, Watal M. Iwasaki, Takashi Makino
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Invaded species often can rapidly expand and establish in novel environments through adaptive evolution, resulting in devastating effects on native communities. However, it is unclear if genetic variation at whole-genomic levels is actually reduced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6533c7a35dfb4fe17a058ab2113b2d2
https://doi.org/10.1038/s41598-017-17852-7
https://doi.org/10.1038/s41598-017-17852-7