Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Wassim G Abou-Kheir"'
Autor:
Orla M Casey, Lei Fang, Paul G Hynes, Wassim G Abou-Kheir, Philip L Martin, Heather S Tillman, Gyorgy Petrovics, Hibah O Awwad, Yvona Ward, Ross Lake, Luhua Zhang, Kathleen Kelly
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41668 (2012)
Genomic rearrangements commonly occur in many types of cancers and often initiate or alter the progression of disease. Here we describe an in vivo mouse model that recapitulates the most frequent rearrangement in prostate cancer, the fusion of the pr
Externí odkaz:
https://doaj.org/article/2af905f70f1c48d0bae2e21c214b0f61
Autor:
Supreet Agarwal, Paul G. Hynes, Heather S. Tillman, Ross Lake, Wassim G. Abou-Kheir, Lei Fang, Orla M. Casey, Amir H. Ameri, Philip L. Martin, Juan Juan Yin, Phillip J. Iaquinta, Wouter R. Karthaus, Hans C. Clevers, Charles L. Sawyers, Kathleen Kelly
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2147-2158 (2015)
Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within tumors. Using the aggressive Pten/Tp53-null mouse model of prostate cancer, we show that two clas
Externí odkaz:
https://doaj.org/article/10f129a7fb434bc989882304f60a11d9
Autor:
Amani Yehya, Alissar Monzer, Kevork Wakimian, Fatima Ghamlouche, Nour Saheb, Ayman Tawil, Hala Gali-Muhtasib, Deborah Mukherji, Albert El-Hajj, Wassim G. Abou-Kheir
Publikováno v:
Cancer Research. 83:5792-5792
Aim: To investigate the anticancer potential of the novel quinone DIQ on prostate cancer (PCa) cells in two-dimensional (2D) and three-dimensional (3D) in vitro. Methods: The anti-proliferative effect of DIQ on PC3 and DU145 PCa cell lines was determ